-
1
-
-
0029023868
-
Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
-
Mineta T, Rabkin SD, Yazaki T, Hunter WD, Martuza RL. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med 1995;1:938-43.
-
(1995)
Nat Med
, vol.1
, pp. 938-943
-
-
Mineta, T.1
Rabkin, S.D.2
Yazaki, T.3
Hunter, W.D.4
Martuza, R.L.5
-
2
-
-
0032505773
-
Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1
-
Toda M, Rabkin SD, Martuza RL. Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1. Hum Gene Ther 1998;9:2177-85.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2177-2185
-
-
Toda, M.1
Rabkin, S.D.2
Martuza, R.L.3
-
3
-
-
0032774578
-
Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207)
-
Kooby DA, Carew JF, Halterman MW, et al. Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207). FASEB J 1999;13:1325-34.
-
(1999)
FASEB J
, vol.13
, pp. 1325-1334
-
-
Kooby, D.A.1
Carew, J.F.2
Halterman, M.W.3
-
4
-
-
0033199929
-
Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207
-
Walker JR, McGeagh KG, Sundaresan P, et al. Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207. Hum Gene Ther 1999;10: 2237-43.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2237-2243
-
-
Walker, J.R.1
McGeagh, K.G.2
Sundaresan, P.3
-
5
-
-
0034950470
-
Effective treatment of head and neck squamous cell carcinoma by an oncolytic herpes simplex virus
-
Wong RJ, Kim SH, Joe JK, et al. Effective treatment of head and neck squamous cell carcinoma by an oncolytic herpes simplex virus. J Am Coll Surg 2001;193:12-21.
-
(2001)
J Am Coll Surg
, vol.193
, pp. 12-21
-
-
Wong, R.J.1
Kim, S.H.2
Joe, J.K.3
-
6
-
-
0034082389
-
Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer
-
Bennett JJ, Kooby DA, Delman K, et al. Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer. J Mol Med 2000;78:166-74.
-
(2000)
J Mol Med
, vol.78
, pp. 166-174
-
-
Bennett, J.J.1
Kooby, D.A.2
Delman, K.3
-
7
-
-
0034632387
-
Intravesical and intravenous therapy of human bladder cancer by the herpes vector G207
-
Oyama M, Ohigashi T, Hoshi M, et al. Intravesical and intravenous therapy of human bladder cancer by the herpes vector G207. Hum Gene Ther 2000;11:1683-93.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 1683-1693
-
-
Oyama, M.1
Ohigashi, T.2
Hoshi, M.3
-
8
-
-
0036657519
-
Replication-competent herpes virus NV 1020 as direct treatment of pleural cancer in a rat model
-
Ebright MI, Zager JS, Malhotra S, et al. Replication-competent herpes virus NV 1020 as direct treatment of pleural cancer in a rat model. J Thorac Cardiovasc Surg 2002;124:123-9.
-
(2002)
J Thorac Cardiovasc Surg
, vol.124
, pp. 123-129
-
-
Ebright, M.I.1
Zager, J.S.2
Malhotra, S.3
-
9
-
-
0036019202
-
Oncolytic herpesvirus effectively treats murine squamous cell carcinoma and spreads by natural lymphatics to treat sites of lymphatic metastases
-
Wong RJ, Joe JK, Kim SH, et al. Oncolytic herpesvirus effectively treats murine squamous cell carcinoma and spreads by natural lymphatics to treat sites of lymphatic metastases. Hum Gene Ther 2002;13: 1213-23.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1213-1223
-
-
Wong, R.J.1
Joe, J.K.2
Kim, S.H.3
-
10
-
-
0033166680
-
Selective infection and cytolysis of human head and neck squamous cell carcinoma with sparing of normal mucosa by a cytotoxic herpes simplex virus type 1 (G207)
-
Carew JF, Kooby DA, Halterman MW, Federoff HJ, Fong Y. Selective infection and cytolysis of human head and neck squamous cell carcinoma with sparing of normal mucosa by a cytotoxic herpes simplex virus type 1 (G207). Hum Gene Ther 1999;10:1599-606.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 1599-1606
-
-
Carew, J.F.1
Kooby, D.A.2
Halterman, M.W.3
Federoff, H.J.4
Fong, Y.5
-
11
-
-
1642535483
-
Effective intravenous therapy of murine pulmonary metastases with an oncolytic herpes virus expressing IL-12
-
Wong RJ, Chan M, Yu Z, et al. Effective intravenous therapy of murine pulmonary metastases with an oncolytic herpes virus expressing IL-12. Clin Cancer Res 2004;10:251-9.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 251-259
-
-
Wong, R.J.1
Chan, M.2
Yu, Z.3
-
12
-
-
12944315014
-
Conditionally replicating herpes simplex virus mutant G207 for the treatment of malignant glioma: Results of a Phase I trial
-
Markert JM, Medlock MD, Rabkin SD, et al. Conditionally replicating herpes simplex virus mutant G207 for the treatment of malignant glioma: results of a Phase I trial. Gene Ther 2000;7:867-74.
-
(2000)
Gene Ther
, vol.7
, pp. 867-874
-
-
Markert, J.M.1
Medlock, M.D.2
Rabkin, S.D.3
-
13
-
-
12944272092
-
Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
-
Rampling R, Cruickshank G, Papanastassiou V, et al. Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther 2000;7:859-66.
-
(2000)
Gene Ther
, vol.7
, pp. 859-866
-
-
Rampling, R.1
Cruickshank, G.2
Papanastassiou, V.3
-
14
-
-
0003059989
-
Phase 1 study of a replication-competent herpes simplex oncolytic virus for treatment of hepatic colorectal metastases
-
Fong Y, Kemeny N, Jarnagin W, et al. Phase 1 study of a replication-competent herpes simplex oncolytic virus for treatment of hepatic colorectal metastases. Proc Am Soc Clin Oncol 2002;21:8a.
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Fong, Y.1
Kemeny, N.2
Jarnagin, W.3
-
15
-
-
20244374204
-
Cytokine gene transfer enhances herpes oncolytic therapy in murine squamous cell carcinoma
-
Wong RJ, Patel SG, Kim SH, et al. Cytokine gene transfer enhances herpes oncolytic therapy in murine squamous cell carcinoma. Hum Gene Ther 2001;12:253-65.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 253-265
-
-
Wong, R.J.1
Patel, S.G.2
Kim, S.H.3
-
16
-
-
0023777661
-
In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020: Construction and evaluation in rodents
-
Meignier B, Longnecker R, Roizman B. In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020: construction and evaluation in rodents. J Infect Dis 1988;158:602-14.
-
(1988)
J Infect Dis
, vol.158
, pp. 602-614
-
-
Meignier, B.1
Longnecker, R.2
Roizman, B.3
-
17
-
-
0025280142
-
In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (aotus trivirgatus)
-
Meignier B, Martin B, Whitley RJ, Roizman B. In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (aotus trivirgatus). J Infect Dis 1990;162:313-21.
-
(1990)
J Infect Dis
, vol.162
, pp. 313-321
-
-
Meignier, B.1
Martin, B.2
Whitley, R.J.3
Roizman, B.4
-
18
-
-
0031963349
-
Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins
-
Andreansky S, He B, van Cott J, et al. Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins. Gene Ther 1998;5:121-30.
-
(1998)
Gene Ther
, vol.5
, pp. 121-130
-
-
Andreansky, S.1
He, B.2
Van Cott, J.3
-
19
-
-
0034050884
-
Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors
-
Parker JN, Gillespie GY, Love CE, et al. Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. Proc Natl Acad Sci USA 2000;97:2208-13.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2208-2213
-
-
Parker, J.N.1
Gillespie, G.Y.2
Love, C.E.3
-
20
-
-
0037384220
-
IL-12: A promising adjuvant for cancer vaccination
-
Portielje JE, Gratama JW, van Ojik HH, Stoter G, Kruit WH. IL-12: a promising adjuvant for cancer vaccination. Cancer Immunol Immunother 2003;52:133-44.
-
(2003)
Cancer Immunol Immunother
, vol.52
, pp. 133-144
-
-
Portielje, J.E.1
Gratama, J.W.2
Van Ojik, H.H.3
Stoter, G.4
Kruit, W.H.5
-
21
-
-
0027239503
-
Antitumor and antimetastatic activity of interleukin-12 against murine tumors
-
Brunda MJ, Luistro L, Warrier RR, et al. Antitumor and antimetastatic activity of interleukin-12 against murine tumors. J Exp Med 178:1223-30.
-
J Exp Med
, vol.178
, pp. 1223-1230
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
-
22
-
-
0029848051
-
Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12
-
Bramson JL, Hitt M, Addison CL, et al. Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12. Hum Gene Ther 1996;7:1995-2002.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1995-2002
-
-
Bramson, J.L.1
Hitt, M.2
Addison, C.L.3
-
23
-
-
0029922177
-
Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10
-
Sgadari C, Angiolillo AL, Tosato G. Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10. Blood 1996;7:3877-82.
-
(1996)
Blood
, vol.7
, pp. 3877-3882
-
-
Sgadari, C.1
Angiolillo, A.L.2
Tosato, G.3
-
25
-
-
0036594813
-
IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16.F10 melanoma
-
Lucas ML, Heller L, Coppola D, Heller R. IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16.F10 melanoma. Mol Ther 2002;5:668-75.
-
(2002)
Mol Ther
, vol.5
, pp. 668-675
-
-
Lucas, M.L.1
Heller, L.2
Coppola, D.3
Heller, R.4
-
26
-
-
0035085442
-
Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity
-
Palmer K, Hitt M, Emtage PC, Gyorffy S, Gauldie J. Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity. Gene Ther 2001;8:282-90.
-
(2001)
Gene Ther
, vol.8
, pp. 282-290
-
-
Palmer, K.1
Hitt, M.2
Emtage, P.C.3
Gyorffy, S.4
Gauldie, J.5
-
27
-
-
0036194917
-
Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature
-
Halin C, Rondini S, Nilsson F, et al. Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature. Nat Biotechnol 2002;20:264-9.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 264-269
-
-
Halin, C.1
Rondini, S.2
Nilsson, F.3
-
28
-
-
0021198726
-
Modification of the effects of continuous low-dose radiation by concurrent chemotherapy infusion
-
Fu KK, Rayner PA, Lam KN. Modification of the effects of continuous low-dose radiation by concurrent chemotherapy infusion. Int J Radiat Oncol Biol Phys 1984;10:1473-8.
-
(1984)
Int J Radiat Oncol Biol Phys
, vol.10
, pp. 1473-1478
-
-
Fu, K.K.1
Rayner, P.A.2
Lam, K.N.3
-
30
-
-
0034835565
-
Characterization of a spontaneously arising murine squamous cell carcinoma (SCC VII) as a prerequisite for head and neck cancer immunotherapy
-
Khurana D, Martin EA, Kasperbauer JL, et al. Characterization of a spontaneously arising murine squamous cell carcinoma (SCC VII) as a prerequisite for head and neck cancer immunotherapy. Head Neck 2001;23:899-906.
-
(2001)
Head Neck
, vol.23
, pp. 899-906
-
-
Khurana, D.1
Martin, E.A.2
Kasperbauer, J.L.3
-
31
-
-
0035869599
-
IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk
-
Strasly M, Cavallo F, Geuna M, et al. IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk. J Immunol 2001;166:3890-9.
-
(2001)
J Immunol
, vol.166
, pp. 3890-3899
-
-
Strasly, M.1
Cavallo, F.2
Geuna, M.3
-
33
-
-
0034036536
-
Conditionally replicating herpes vectors for cancer therapy
-
Martuza RL. Conditionally replicating herpes vectors for cancer therapy. J Clin Investig 2000;105:841-6.
-
(2000)
J Clin Investig
, vol.105
, pp. 841-846
-
-
Martuza, R.L.1
-
34
-
-
0033104852
-
Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12
-
Yao L, Sgadari C, Furuke K, et al. Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12. Blood 1999;93: 1612-21.
-
(1999)
Blood
, vol.93
, pp. 1612-1621
-
-
Yao, L.1
Sgadari, C.2
Furuke, K.3
-
35
-
-
0033589694
-
Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus
-
Todo T, Rabkin SD, Sundaresan P, et al. Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Hum Gene Ther 1999;10: 2741-55.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2741-2755
-
-
Todo, T.1
Rabkin, S.D.2
Sundaresan, P.3
|