Structure-activity relationships of the didemnins

Journal of Medicinal Chemistry

Volumn 39, Issue 14, 1996, Pages 2819-2834

  Sakai, Ryuichi ^a   Rinehart, Kenneth L ^a   Kishore, Vimal ^a   Kundu, Bijoy ^a   Faircloth, Glynn ^b,c   Gloer, James B ^a   Carney, John R ^a   Namikoshi, Michio ^a   Sun, Furong ^a   Hughes Jr , Robert G ^d   Grávalos, Dolores García ^b,c   De Quesada, Teresa García ^b,c   Wilson, George R ^a   Heid, Richard M ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b PharmaMar USA Inc   (United States)

^c PHARMAMAR S A   (Spain)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; DIDEMNIN A; DIDEMNIN B; DIHYDROFOLATE REDUCTASE INHIBITOR; DNA POLYMERASE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); GYRASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT; RNA POLYMERASE; THYMIDYLATE SYNTHASE;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CLINICAL TRIAL; CYTOTOXICITY; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; GROWTH INHIBITION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MARINE ENVIRONMENT; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PROTEIN SYNTHESIS INHIBITION; STRUCTURE ACTIVITY RELATION; TUMOR CELL CULTURE; VESICULAR STOMATITIS VIRUS;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CRICETINAE; DEPSIPEPTIDES; DNA; ENZYMES; FEMALE; HERPESVIRUS 1, HUMAN; HT29 CELLS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; MOLECULAR STRUCTURE; PEPTIDES, CYCLIC; PROTEIN BIOSYNTHESIS; PROTEINS; RNA; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; UROCHORDATA; VESICULAR STOMATITIS-INDIANA VIRUS;

EID: 8944252332     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960048g     Document Type: Article

References (63)

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