Polyenoic fatty acid ratios alter fibroblast collagen production via PGE2 and PGE receptor subtype response

Experimental Biology and Medicine

Volumn 229, Issue 7, 2004, Pages 676-683

  Jia, Yi ^a   Turek, John J ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Collagen; Fibroblast; Omega 3 fatty acids; Omega 6 fatty acids; PGE2

Indexed keywords

ARACHIDONIC ACID; BOVINE SERUM ALBUMIN; CELL PROTEIN; COLLAGEN; FATTY ACID; ICOSAPENTAENOIC ACID; INDOMETACIN; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E1 RECEPTOR; PROSTAGLANDIN E2; PROSTAGLANDIN E4 RECEPTOR; PROSTAGLANDIN SYNTHASE INHIBITOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DETERMINATION; ENZYME ACTIVATION; FIBROBLAST; LIPID COMPOSITION; LIPID DIET; MOUSE; NONHUMAN; PROSTAGLANDIN SYNTHESIS;

ANIMALIA; BOVINAE;

EID: 3042734828     PISSN: 15353702     EISSN: None     Source Type: Journal    
DOI: 10.1177/153537020422900712     Document Type: Article

References (27)

1. Eickelberg O, Kohler E, Reichenberger F, Bertschin S, Woodtli T, Erne P, Roth M. Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-1 and TGF-3. Am J Physiol Lung Cell Mol Physiol 276:L814-L824, 1999.
2. Dowdy PA, Miniaci A, Arnoczky SP, Fowler PJ, Boughner DR. The effect of cast immobilization on meniscal healing. An experimental study in the dog. Am J Sports Med 23:721-728, 1995.
3. Ghosh AK. Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp Biol Med 227:301-314, 2002.
4. Cutroneo KR. How is type I procollagen synthesis regulated at the gene level during tissue fibrosis. J Cell Biochem 90:1-5, 2003.
5. Wang JF, Olson ME, Ball DK, Brigstock DR, Hart DA. Recombinant connective tissue growth factor modulates porcine skin fibroblast gene expression. Wound Repair Regen 11:220-229, 2003.
6. Oshiro W, Lou J, Xing X, Tu Y, Manske P. Flexor tendon healing in the rat: a histologic and gene expression study. J Hand Surg 28:814-823, 2003.
7. Li S, Van Den Diepstraten C, D'Souza SJ, Chan BMC, Pickering JG. Vascular smooth muscle cells orchestrate the assembly of type I collagen via alpha2beta1 integrin, RhoA, and fibronectin polymerization. Am J Pathol 163:1045-1056, 2003.
8. Watkins BA, Xu H, Turek JJ. Linoleate impairs collagen synthesis in primary cultures of avian chondrocytes. Proc Soc Exp Biol Med 212:153-159, 1996.
9. Hankenson KD, Watkins BA, Schoenlein IA, Allen KG, Turek JJ. Omega-3 fatty acids enhance ligament fibroblast collagen formation in association with changes in interleukin-6 production. Exp Biol Med 223:88-95, 2000.
10. Riquet FB, Lai WF, Birkhead JR, Suen LF, Karsenty G, Goldring MB. Suppression of type 1 collagen gene expression by prostaglandins in fibroblasts is mediated at the transcriptional level. Mol Med 6:705-719, 2000.
11. Hwang D. Fatty acids and immune responses - a new perspective in searching for clues to mechanism. Ann Rev Nutr 20:431-456, 2000.
12. Turek JJ, Schoenlein IA. Altered gene expression in 3T3 fibroblasts enriched with different polyunsaturated fatty acids. Faseb J 16:A263, 2002.
13. Varga J, Diaz-Perez A, Rosenbloom J, Jimenez SA. PGE2 causes a coordinate decrease in the steady state levels of fibronectin and types I and III procollagen mRNAs in normal human dermal fibroblasts. Biochem Biophys Res Commun 147:1282-1288, 1987.
14. Barnett J, Chow J, Ives D, Chiou M, Mackenzie R, Osen E, Nguyen B, Tsing S, Bach C, Freire J, Chan H, Sigal E, Ramesha C. Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system. Biochim Biophys Acta 1209:130-139, 1994.
15. Bagga D, Wang L, Eisner RF, Glaspy JA, Reddy ST. Differential effects of prostaglandin derived from ω-6 and ω-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc Natl Acad Sci U S A 100:1751-1756, 2003.
16. Broughton KS, Wade JW. Total fat and (n-3):(n-6) fat ratios influence eicosanoid production in mice. J Nutr 132:88-94, 2002.
17. Coleman RA, Smith WL, Narumiya S. International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol Rev 46:205-229, 1994.
18. Choung J, Taylor L, Thomas K, Zhou X, Kagan H, Yang X, Polgar P. Role of EP2 receptors and cAMP in prostaglandin E2 regulated expression of type I collagen alpha1, lysyl oxidase, and cyclooxygenase-1 genes in human embryo lung fibroblasts. J Cell Biochem 71:254-263, 1998.
19. Noguchi K, Shitashige M, Endo H, Kondo H, Ishikawa I. Binary regulation of interleukin(IL)6 production by EP1 and EP2/EP4 subtypes of PGE2 receptors in IL1stimulated human gingival fibroblasts. J Periodont Res 37:29-36, 2002.
20. Sakai Y, Fujita K, Sakai H, Mizuno K. Prostaglandin E2 regulates the expression of basic fibroblast growth factor messenger RNA in normal human fibroblasts. Kobe J Med Sci 47:35-45, 2003.
21. Sellmayer A, Danesch U, Weber PC. Effects of different polyunsaturated fatty acids on growth-related early gene expression and cell growth. Lipids 31(Suppl):S37-S40, 1996.
22. Chen Y, Hughes FM. Prostaglandin E2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cells. Br J Cancer 82:2000-2006, 2000.
23. Schwartz Z, Gilley RM, Sylvia VL, Dean DD, Boyan BD. The effect of prostaglandin E2 on costochondral chondrocyte differentiation is mediated by cyclic adenosine 3′,5′-monophosphate and protein kinase C. Endocrinology 139:1825-1834, 1998.
24. Zhu YK, Liu XD, Skold MC, Umino T, Wang H, Romberger DJ, Spurzem JR, Kohyama T, Wen FQ, Rennard SI. Cytokine inhibition of fibroblast-induced gel contraction is mediated by PGE2 and NO acting through separate parallel pathways. Am J Respir Cell Mol Biol 25:245-253, 2001.
25. Sonoshita M, Takaku K, Sasaki N, Sugimoto Y, Ushikubi F, Narumiya S, Oshima M, Taketo MM. Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc716 knockout mice. Nature Med 7:1048-1051, 2001.
26. Zhang YH, Lin JX, Vilcek J. Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence. Mol Cell Biol 10:3818-3823, 1990.
27. Cutroneo KR, Phan SH. TGF-beta1-induced Smad 3 binding to the Smad 7 gene: knockout of Smad 7 gene transcription by sense phosphorothioate oligos, autoregulation, and effect on TGF-beta1 secretion: bleomycin acts through TGF-beta1. J Cell Biochem 89:474-483, 2003.