-
1
-
-
0032547272
-
Induction of inhibitory Smad 6 and Smad 7 mRNA by TGF-β family members
-
Afrakhte M, Moren A, Jossan S, Itoh S, Sampath K, Westermark B, Heldin CH, Heldin NE, ten Dijke P. 1998. Induction of inhibitory Smad 6 and Smad 7 mRNA by TGF-β family members. Biochem Biophys Res Comm 249:505-511.
-
(1998)
Biochem Biophys Res Comm
, vol.249
, pp. 505-511
-
-
Afrakhte, M.1
Moren, A.2
Jossan, S.3
Itoh, S.4
Sampath, K.5
Westermark, B.6
Heldin, C.H.7
Heldin, N.E.8
Ten Dijke, P.9
-
2
-
-
0024397094
-
Synergistic enhancement of type I and type III collagen production in cultured fibroblasts by transforming growth factor-β and ascorbate
-
Appling WD, O'Brien WR, Johnston DA, Duvic M. 1989. Synergistic enhancement of type I and type III collagen production in cultured fibroblasts by transforming growth factor-β and ascorbate. Fed Eur Biochem 250: 541-544.
-
(1989)
Fed Eur Biochem
, vol.250
, pp. 541-544
-
-
Appling, W.D.1
O'Brien, W.R.2
Johnston, D.A.3
Duvic, M.4
-
3
-
-
0026813956
-
Bleomycin regulation of transforming growth factor-β expression in bleomycin-induced pulmonary fibrosis
-
Breen E, Shull S, Burne S, Absher M, Kelley J, Phan S, Cutroneo KR. 1992. Bleomycin regulation of transforming growth factor-β expression in bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol 6:146-152.
-
(1992)
Am J Respir Cell Mol Biol
, vol.6
, pp. 146-152
-
-
Breen, E.1
Shull, S.2
Burne, S.3
Absher, M.4
Kelley, J.5
Phan, S.6
Cutroneo, K.R.7
-
4
-
-
0034666152
-
Efficient TGF-β induction of the Smad 7 gene requires cooperation between AP-1, Sp1 and Smad proteins on the mouse Smad 7 promoter
-
Brodin G, Ahgren A, ten Dijke P, Heldin CH, Heuchel R. 2000. Efficient TGF-β induction of the Smad 7 gene requires cooperation between AP-1, Sp1 and Smad proteins on the mouse Smad 7 promoter. J Biol Chem 275:29023-29030.
-
(2000)
J Biol Chem
, vol.275
, pp. 29023-29030
-
-
Brodin, G.1
Ahgren, A.2
Ten Dijke, P.3
Heldin, C.H.4
Heuchel, R.5
-
5
-
-
0023392945
-
High-efficiency transformation of mammalian cells by plasmid DNA
-
Chen C, Okayama H. 1987. High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7:2745-2752.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 2745-2752
-
-
Chen, C.1
Okayama, H.2
-
6
-
-
0031059572
-
Transforming growth factors β1, β2, and β3 stimulate fibroblast procollagen production in vitro but are differentially expressed during bleomycin-induced lung fibrosis
-
Coker RK, Laurent GJ, Shahzeidi S, Lympany PA, duBois RM, Jeffrey PK, McAnulty RJ. 1997. Transforming growth factors β1, β2, and β3 stimulate fibroblast procollagen production in vitro but are differentially expressed during bleomycin-induced lung fibrosis. Am J Pathol 150:981-991.
-
(1997)
Am J Pathol
, vol.150
, pp. 981-991
-
-
Coker, R.K.1
Laurent, G.J.2
Shahzeidi, S.3
Lympany, P.A.4
DuBois, R.M.5
Jeffrey, P.K.6
McAnulty, R.J.7
-
7
-
-
0032101178
-
Direct binding of Smad 3 and Smad 4 to critical TGF-β inducible elements in the promoter of human plasminogen activator inhibitor-type I gene
-
Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. 1998. Direct binding of Smad 3 and Smad 4 to critical TGF-β inducible elements in the promoter of human plasminogen activator inhibitor-type I gene. EMBO J 17:3091-3100.
-
(1998)
EMBO J
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
8
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam JD, Lebovitz RM, Roeder RG. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
9
-
-
0027425864
-
Effect of antibody to transforming growth factor β on bleomycin induced accumulation of lung collagen in mice
-
Giri SN, Hyde DM, Hollinger MA. 1993. Effect of antibody to transforming growth factor β on bleomycin induced accumulation of lung collagen in mice. Thorax 48:959-966.
-
(1993)
Thorax
, vol.48
, pp. 959-966
-
-
Giri, S.N.1
Hyde, D.M.2
Hollinger, M.A.3
-
10
-
-
0032475984
-
Collagen type XVI expression is modulated by basic fibroblast growth factor and transforming growth factor-β
-
Grassel S, Tan EM, Timpl R, Chu ML. 1998. Collagen type XVI expression is modulated by basic fibroblast growth factor and transforming growth factor-β. FEBS Lett 436:197-201.
-
(1998)
FEBS Lett
, vol.436
, pp. 197-201
-
-
Grassel, S.1
Tan, E.M.2
Timpl, R.3
Chu, M.L.4
-
11
-
-
0030854850
-
Sp1 is required for the early response of α2(I) collagen to transforming growth factor-β1
-
Greenwel P, Inagaki Y, Hu W, Walsh M, Ramirez F. 1997. Sp1 is required for the early response of α2(I) collagen to transforming growth factor-β1. J Biol Chem 272:19738-19745.
-
(1997)
J Biol Chem
, vol.272
, pp. 19738-19745
-
-
Greenwel, P.1
Inagaki, Y.2
Hu, W.3
Walsh, M.4
Ramirez, F.5
-
12
-
-
0029124143
-
Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: Down regulation of TGF-β and procollagen I and III gene expression
-
Gurujeyalakshmi G, Giri SN. 1995. Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: Down regulation of TGF-β and procollagen I and III gene expression. Expt Lung Res 21:791-808.
-
(1995)
Expt Lung Res
, vol.21
, pp. 791-808
-
-
Gurujeyalakshmi, G.1
Giri, S.N.2
-
14
-
-
0034721771
-
Synergism between transcription factors TFE3 and Smad 3 in transforming growth factor β-induced transcription of the Smad 7 gene
-
Hua X, Miller ZA, Benchabane H, Wrana JL, Lodish HF. 2000. Synergism between transcription factors TFE3 and Smad 3 in transforming growth factor β-induced transcription of the Smad 7 gene. J Biol Chem 275:33205-33208.
-
(2000)
J Biol Chem
, vol.275
, pp. 33205-33208
-
-
Hua, X.1
Miller, Z.A.2
Benchabane, H.3
Wrana, J.L.4
Lodish, H.F.5
-
15
-
-
0023025366
-
Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
-
Ignotz RA, Massague J. 1986. Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 261:4337-4345.
-
(1986)
J Biol Chem
, vol.261
, pp. 4337-4345
-
-
Ignotz, R.A.1
Massague, J.2
-
16
-
-
0028176086
-
Transforming growth factor-β stimulates α2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site
-
Inagaki Y, Truter S, Ramirez F. 1994. Transforming growth factor-β stimulates α2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site. J Biol Chem 269:14828-14834.
-
(1994)
J Biol Chem
, vol.269
, pp. 14828-14834
-
-
Inagaki, Y.1
Truter, S.2
Ramirez, F.3
-
17
-
-
0034533657
-
Signaling of transforming growth factor-β family members through Smad proteins
-
Itoh S, Itoh F, Goumans MJ, ten Dijke P. 2000a. Signaling of transforming growth factor-β family members through Smad proteins. Eur J Biochem 267:6954-6967.
-
(2000)
Eur J Biochem
, vol.267
, pp. 6954-6967
-
-
Itoh, S.1
Itoh, F.2
Goumans, M.J.3
Ten Dijke, P.4
-
18
-
-
0034326828
-
The transcriptional co-activator P/CAF potentiates TGF-β/Smad signaling
-
Itoh S, Ericsson J, Nishikawa J, Heldin CH, ten Dijke P. 2000b. The transcriptional co-activator P/CAF potentiates TGF-β/Smad signaling. Nucleic Acids Res 28:4291-4298.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 4291-4298
-
-
Itoh, S.1
Ericsson, J.2
Nishikawa, J.3
Heldin, C.H.4
Ten Dijke, P.5
-
19
-
-
0028279513
-
Functional analysis of human α1(I) procollagen gene promoter
-
Jimenez SA, Varga J, Olsen A, Li L, Diaz A, Herhal J, Koch J. 1994. Functional analysis of human α1(I) procollagen gene promoter. J Biol Chem 269:12684-12691.
-
(1994)
J Biol Chem
, vol.269
, pp. 12684-12691
-
-
Jimenez, S.A.1
Varga, J.2
Olsen, A.3
Li, L.4
Diaz, A.5
Herhal, J.6
Koch, J.7
-
20
-
-
0032516862
-
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin and bone morphogenic protein-inducible enhancer
-
Jonk LJ, Itoh S, Heldin CH, ten Dijke P, Kruijer W. 1998. Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin and bone morphogenic protein-inducible enhancer. J Biol Chem 273:21145-21152.
-
(1998)
J Biol Chem
, vol.273
, pp. 21145-21152
-
-
Jonk, L.J.1
Itoh, S.2
Heldin, C.H.3
Ten Dijke, P.4
Kruijer, W.5
-
21
-
-
0028181718
-
Bleomycin stimulates pro-alpha 1 (I) collagen promoter through transforming growth factor beta response element by intracellular and extracellular signaling
-
King SL, Lichtler AC, Rowe DW, Xie R, Long GL, Absher MP, Cutroneo KR. 1994. Bleomycin stimulates pro-alpha 1 (I) collagen promoter through transforming growth factor beta response element by intracellular and extracellular signaling. J Biol Chem 269:13156-13161.
-
(1994)
J Biol Chem
, vol.269
, pp. 13156-13161
-
-
King, S.L.1
Lichtler, A.C.2
Rowe, D.W.3
Xie, R.4
Long, G.L.5
Absher, M.P.6
Cutroneo, K.R.7
-
22
-
-
0033865273
-
Regulatory mechanisms for transforming growth factor β as an autocrine inhibitor in human hepatocellular carcinoma: Implications for roles of smads in its growth
-
Matsuzaki K, Date M, Furukawa F, Tahashi Y, Matsushita M, Sugano Y, Yamashiki N, Nakagawa T, Seki T, Nishizawa M, Fujisawa J, Inoue K. 2000. Regulatory mechanisms for transforming growth factor β as an autocrine inhibitor in human hepatocellular carcinoma: Implications for roles of smads in its growth. Hepatology 32:218-227.
-
(2000)
Hepatology
, vol.32
, pp. 218-227
-
-
Matsuzaki, K.1
Date, M.2
Furukawa, F.3
Tahashi, Y.4
Matsushita, M.5
Sugano, Y.6
Yamashiki, N.7
Nakagawa, T.8
Seki, T.9
Nishizawa, M.10
Fujisawa, J.11
Inoue, K.12
-
23
-
-
0034016101
-
Positive and negative regulation of TGF-β signaling
-
Miyazono K. 2000. Positive and negative regulation of TGF-β signaling. J Cell Sci 113:1101-1109.
-
(2000)
J Cell Sci
, vol.113
, pp. 1101-1109
-
-
Miyazono, K.1
-
24
-
-
0032719815
-
Transfer and expression of Smad 7 prevents bleomycin-induced lung fibrosis in mice
-
Nakao A, Fujii M, Matsumura R, Kumano Y, Saito Y, Miyazono K, Iwamoto I. 1999. Transfer and expression of Smad 7 prevents bleomycin-induced lung fibrosis in mice. J Clin Invest 104:5-11.
-
(1999)
J Clin Invest
, vol.104
, pp. 5-11
-
-
Nakao, A.1
Fujii, M.2
Matsumura, R.3
Kumano, Y.4
Saito, Y.5
Miyazono, K.6
Iwamoto, I.7
-
25
-
-
0025776771
-
Activation of collagen gene expression in keloids: Co-localization of type I and VI collagen and transforming growth factor-β1 mRNA
-
Peltonen J, Hsiao LL, Jaakkola S, Sollberg S, Aumailley M, Timpl R, Chu ML. 1991. Activation of collagen gene expression in keloids: Co-localization of type I and VI collagen and transforming growth factor-β1 mRNA. J Invest Dermatol 97:240-248.
-
(1991)
J Invest Dermatol
, vol.97
, pp. 240-248
-
-
Peltonen, J.1
Hsiao, L.L.2
Jaakkola, S.3
Sollberg, S.4
Aumailley, M.5
Timpl, R.6
Chu, M.L.7
-
26
-
-
0026076135
-
Transforming growth factor-β activation elements in the distal promoter regions of the rat α1 type I collagen gene
-
Ritzenthaler JD, Goldstein RH, Fine A, Lichtler A, Rowe DW, Smith BD. 1991. Transforming growth factor-β activation elements in the distal promoter regions of the rat α1 type I collagen gene. Biochem J 280:157-162.
-
(1991)
Biochem J
, vol.280
, pp. 157-162
-
-
Ritzenthaler, J.D.1
Goldstein, R.H.2
Fine, A.3
Lichtler, A.4
Rowe, D.W.5
Smith, B.D.6
-
27
-
-
0027378273
-
Regulation of the α1(I) collagen promoter via a transforming growth factor-β activation element
-
Ritzenthaler JD, Goldstein RH, Fine A, Smith BD. 1993. Regulation of the α1(I) collagen promoter via a transforming growth factor-β activation element. J Biol Chem 268:13625-13631.
-
(1993)
J Biol Chem
, vol.268
, pp. 13625-13631
-
-
Ritzenthaler, J.D.1
Goldstein, R.H.2
Fine, A.3
Smith, B.D.4
-
28
-
-
0024263315
-
Transforming growth factor β: Multiple effects of cell differentiation and extracellular matrices
-
Rizzino A. 1988. Transforming growth factor β: Multiple effects of cell differentiation and extracellular matrices. Dev Biol 130:411-422.
-
(1988)
Dev Biol
, vol.130
, pp. 411-422
-
-
Rizzino, A.1
-
29
-
-
0022471924
-
Transforming growth factor of type β: Rapid induction of fibrosis and antiogenesis in vivo and stimulation of collagen formation in vitro
-
Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH, Fauci AS. 1986. Transforming growth factor of type β: Rapid induction of fibrosis and antiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 83:4167-4171.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 4167-4171
-
-
Roberts, A.B.1
Sporn, M.B.2
Assoian, R.K.3
Smith, J.M.4
Roche, N.S.5
Wakefield, L.M.6
Heine, U.I.7
Liotta, L.A.8
Falanga, V.9
Kehrl, J.H.10
Fauci, A.S.11
-
30
-
-
0023856558
-
A nuclear factor I binding site mediates the transcriptional activation of type I collagen promoter by transforming growth factor-β
-
Rossi P, Karsenty G, Roberts AB, Roche NS, Sporn MB, de Crombrugghe B. 1988. A nuclear factor I binding site mediates the transcriptional activation of type I collagen promoter by transforming growth factor-β. Cell 52:405-414.
-
(1988)
Cell
, vol.52
, pp. 405-414
-
-
Rossi, P.1
Karsenty, G.2
Roberts, A.B.3
Roche, N.S.4
Sporn, M.B.5
De Crombrugghe, B.6
-
31
-
-
0024382711
-
Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factors β1-like molecule by plasmin during co-culture
-
Sato Y, Rifkin DB. 1989. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factors β1-like molecule by plasmin during co-culture. J Cell Biol 109:309-315.
-
(1989)
J Cell Biol
, vol.109
, pp. 309-315
-
-
Sato, Y.1
Rifkin, D.B.2
-
32
-
-
0031773264
-
TGF-β-induced phosphorylation of Smad 3 regulates its interaction with coactivator p300/CREB-binding protein
-
Shen X, Hu PP, Liberati NT, Datto MB, Frederick JP, Wang XF. 1998. TGF-β-induced phosphorylation of Smad 3 regulates its interaction with coactivator p300/CREB-binding protein. Mol Biol Cell 9:3309-3319.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 3309-3319
-
-
Shen, X.1
Hu, P.P.2
Liberati, N.T.3
Datto, M.B.4
Frederick, J.P.5
Wang, X.F.6
-
33
-
-
0033515587
-
Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor β-induced Smad-dependent transcriptional activation
-
Stroschein SL, Wang W, Luo K. 1999. Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor β-induced Smad-dependent transcriptional activation. J Biol Chem 274:9431-9441.
-
(1999)
J Biol Chem
, vol.274
, pp. 9431-9441
-
-
Stroschein, S.L.1
Wang, W.2
Luo, K.3
-
34
-
-
0034595653
-
Induction of platelet-derived growth factor B-chain expression by transforming growth factor-β involves transactivation by Smads
-
Taylor LM, Khachigian LM. 2000. Induction of platelet-derived growth factor B-chain expression by transforming growth factor-β involves transactivation by Smads. J Biol Chem 275:16709-16716.
-
(2000)
J Biol Chem
, vol.275
, pp. 16709-16716
-
-
Taylor, L.M.1
Khachigian, L.M.2
-
35
-
-
0032428684
-
SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor
-
Tsukazaki T, Chiang TA, Davison AF, Attisano L, Wrana JL. 1998. SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor. Cell 95:779-791.
-
(1998)
Cell
, vol.95
, pp. 779-791
-
-
Tsukazaki, T.1
Chiang, T.A.2
Davison, A.F.3
Attisano, L.4
Wrana, J.L.5
-
36
-
-
0033602101
-
Inhibition of transforming growth factor-β/SMAD signaling by the interferon-gamma/STAT pathway
-
Ulloa L, Doody J, Massague J. 1999. Inhibition of transforming growth factor-β/SMAD signaling by the interferon-gamma/STAT pathway. Nature 397:710-713.
-
(1999)
Nature
, vol.397
, pp. 710-713
-
-
Ulloa, L.1
Doody, J.2
Massague, J.3
-
37
-
-
0022531313
-
Stimulation of normal human fibroblast collagen production and processing by transforming growth factor-β
-
Varga J, Jimenez JA. 1986. Stimulation of normal human fibroblast collagen production and processing by transforming growth factor-β. Biochem Biophys Res Commun 138:974-980.
-
(1986)
Biochem Biophys Res Commun
, vol.138
, pp. 974-980
-
-
Varga, J.1
Jimenez, J.A.2
-
38
-
-
0032557674
-
Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-β
-
Vindevoghel L, Kon A, Lechleider RJ, Uitto J, Roberts AB, Mauviel A. 1998. Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-β. J Biol Chem 273:13053-13057.
-
(1998)
J Biol Chem
, vol.273
, pp. 13053-13057
-
-
Vindevoghel, L.1
Kon, A.2
Lechleider, R.J.3
Uitto, J.4
Roberts, A.B.5
Mauviel, A.6
-
39
-
-
0034646674
-
Smad 3 and Smad 4 mediate transcriptional activation of the human Smad 7 promoter by transforming growth factor β
-
Von Gersdorff G, Susztak K, Revani F, Bitzer M, Liang D, Bottinger EP. 2000. Smad 3 and Smad 4 mediate transcriptional activation of the human Smad 7 promoter by transforming growth factor β. J Biol Chem 275:11320-11326.
-
(2000)
J Biol Chem
, vol.275
, pp. 11320-11326
-
-
Von Gersdorff, G.1
Susztak, K.2
Revani, F.3
Bitzer, M.4
Liang, D.5
Bottinger, E.P.6
-
40
-
-
0034595970
-
Transcriptional regulation of the transforming growth factor-β-inducible mouse germ line Ig alpha constant region gene by functional cooperation of Smad, CREB and AML family members
-
Zhang Y, Derynck R. 2000. Transcriptional regulation of the transforming growth factor-β-inducible mouse germ line Ig alpha constant region gene by functional cooperation of Smad, CREB and AML family members. J Biol Chem 275:16979-16985.
-
(2000)
J Biol Chem
, vol.275
, pp. 16979-16985
-
-
Zhang, Y.1
Derynck, R.2
-
41
-
-
0029115157
-
Cellular localization of transforming growth factor-β expression in bleomycin-induced pulmonary fibrosis
-
Zhang K, Flanders KC, Phan SH. 1995. Cellular localization of transforming growth factor-β expression in bleomycin-induced pulmonary fibrosis. Am J Pathol 147: 352-361.
-
(1995)
Am J Pathol
, vol.147
, pp. 352-361
-
-
Zhang, K.1
Flanders, K.C.2
Phan, S.H.3
-
42
-
-
0034671506
-
Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor-β stimulation of α2(I) collagen (COL1A2) transcription
-
Zhang W, Ou J, Inagaki Y, Grenwel P, Ramirez F. 2000. Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor-β stimulation of α2(I) collagen (COL1A2) transcription. J Biol Chem 275:39237-39245.
-
(2000)
J Biol Chem
, vol.275
, pp. 39237-39245
-
-
Zhang, W.1
Ou, J.2
Inagaki, Y.3
Grenwel, P.4
Ramirez, F.5
-
43
-
-
0036086293
-
Smad 3 deficiency attenuated bleomycin-induced pulmonary fibrosis in mice
-
Zhao J, Shi W, Wang YL, Chen H, Bringas PJR, Datto MB, Frederick JP, Wang XF, Warburton D. 2002. Smad 3 deficiency attenuated bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell and Mol Physiol 282:L585-L593.
-
(2002)
Am J Physiol Lung Cell and Mol Physiol
, vol.282
-
-
Zhao, J.1
Shi, W.2
Wang, Y.L.3
Chen, H.4
Bringas, P.J.R.5
Datto, M.B.6
Frederick, J.P.7
Wang, X.F.8
Warburton, D.9
|