Stereoselective hepatic disposition of model diastereomeric acyl glucuronides

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 31, Issue 1, 2004, Pages 1-27

  Shackleford, David M ^a   Nation, Roger L ^a   Milne, R W ^a   Hayball, P J ^a   Evans, Allan M ^a  

^a Centre for Pharmaceutical Research   (Australia)

Author keywords

acyl glucuronides; distereomers; Hepatic Disposition; hepatocyte; impulse response; perfused liver; stereo selectivity; transport

Indexed keywords

2 PHENYLPROPIONIC ACID GLUCURONIDE; CARBON 14; GLUCURONIDE; HYDRATROPIC ACID; SUCROSE; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIASTEREOISOMER; ISOLATED LIVER; KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOCHEMISTRY;

1-OCTANOL; ACYLATION; ANIMALS; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONIDES; LIVER; MALE; MODELS, BIOLOGICAL; PERFUSION; PHENYLPROPIONATES; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; TIME FACTORS;

EID: 3042726650     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOPA.0000029486.60317.25     Document Type: Article

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