Highly active antiretroviral therapy and sexual risk behavior: A meta-analytic review

JAMA

Volumn 292, Issue 2, 2004, Pages 224-236

  Crepaz, Nicole ^a   Hart, Trevor A ^a,b,c   Marks, Gary ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YORK UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIBLIOGRAPHIC DATABASE; CONDOM; HETEROSEXUALITY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOMOSEXUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; META ANALYSIS; PRIORITY JOURNAL; REVIEW; SAFE SEX; SEXUAL BEHAVIOR; SEXUAL INTERCOURSE; SEXUALLY TRANSMITTED DISEASE; STATISTICAL ANALYSIS; SYSTEMATIC REVIEW; VIRUS LOAD; VIRUS TRANSMISSION; ARTICLE; ATTITUDE TO HEALTH; CLINICAL TRIAL; HIGH RISK BEHAVIOR; STATISTICS;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HIV INFECTIONS; HUMANS; RISK-TAKING; SEXUAL BEHAVIOR; VIRAL LOAD;

EID: 3042723521     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.292.2.224     Document Type: Review

References (74)

1. Dionisio D, Vivarelli A, Zazzi M, Esperti F, Uberti M, Polidori P. Extent of human immunodeficiency virus type 1 drug resistance as a predictor of virological failure after genotype-guided treatment switch. Clin Infect Dis. 2001;33:706-709.
2. Wainberg MA, Freidland G. Public health implications of antiretroviral therapy and HIV drug resistance. JAMA. 1998;279:1977-1983.
3. Lucas GM, Chaisson RE, Moore RD. Highly Active antiretroviral therapy in a large urban clinic. Ann Intern Med. 1999;131:81-87.
4. Friedland GH, Williams A. Attaining higher goals in HIV treatment. AIDS. 1999;13(suppl 1):S61-S72.
5. Carpenter CC, Fischl MA, Hammer SM, et al. Antiviral therapy for HIV infection in 1997. JAMA. 1997; 277:1962-1969.
6. Montaner JS, Reiss P, Cooper D, et al. A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients. JAMA. 1998;279:930-937.
7. Deeks SG, Smith M, Holodniy M, Kahn JO. HIV-1 protease inhibitors. JAMA. 1997;277:145-153.
8. Posner SF, Marks G. Prevalence of high-risk sex among HIV-positive gay and bisexual men: a longitudinal analysis. Am J Prev Med. 1996;12:472-477.
9. Mocroft A, Vella S, Benfield TL, et al. Changing patterns of mortality across Europe in patients infected with HIV-1. Lancet. 1998;352:1725-1730.
10. Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med. 1998;338:853-860.
11. Chen SY, Gibson S, Katz MH, et al. Continuing increases in sexual risk behavior and sexually transmitted diseases among men who have sex with men. Am J Public Health. 2002;92:1387-1388.
12. Katz MH, Schwarcz SK, Kellogg TA, et al. Impact of highly active antiretroviral treatment on HIV sero-incidence among men who have sex with men: San Francisco. Am J Public Health. 2002;92:388-394.
13. Dodds JP, Nardone A, Mercey DE, Johnson AM. Increase in high-risk sexual behavior among homosexual men, London, 1996-8. BMJ. 2000;320:1510-1511.
14. Wolitski RJ, Valdiserri RO, Denning PH, Levine WC. Are we headed for a resurgence of the HIV epidemic among men who have sex with men? Am J Public Health. 2001;91:883-888.
15. Increases in unsafe sex and rectal gonorrhea among men who have sex with men - San Francisco 1994-97. MMWR Morb Mortal Wkly Rep. 1999;48:45-48.
16. Stolte IG, Dukers NH, de Wit JB, Fennema JS, Coutinho RA. Increase in sexually transmitted infections among homosexual men in Amsterdam in relation to HAART. Sex Transm Infect. 2001;77:184-186.
17. Hogg RS, Weber AE, Chan K, et al. Increasing incidence of HIV infections among young gay and bisexual men in Vancouver. AIDS. 2001;15:1321-1322.
18. Dukers NH, Spaargaren J, Geskus RB, Beijnen J, Coutinho RA, Fennema HS. HIV incidence on the increase among homosexual men attending an Amsterdam sexually transmitted disease clinic. AIDS. 2002; 16:F19-F24.
19. Yamey C. San Francisco's HIV infection rate doubles. BMJ. 2001;322:260.
20. Increases in HIV diagnoses - 29 states, 1999-2002. MMWR Morb Mortal Wkly Rep. 2003;52: 1145-1148.
21. Quinn TC, Wawer MJ, Sewankambo N, et al, for the Rakai Project Study Group. Viral load and heterosexual transmission of human immunodeficiency virus type 1. N Engl J Med. 2000;342:921-929.
22. Pedraza MA, del Romero J, Roldan F, et al. Heterosexual transmission of HIV-1 is associated with high plasma viral load levels and a positive viral isolation in the infected partner. J Acquir Immune Defic Syndr. 1999;21:120-125.
23. Fideli U, Allen S, Musonda R, et al. Virologic determinants of heterosexual transmission in Africa. In: Program and abstracts of the 7th Conference on Retroviruses and Opportunistic Infections; January 30-February 2, 2000; San Francisco, Calif.
24. Zhang H, Dornadula G, Beumont M, et al. Human immunodeficiency virus type 1 in the semen of men receiving highly active antiretroviral therapy. N Engl J Med. 1998;339:1803-1809.
25. Tachet A, Dulioust E, Salmon D, et al. Detection and quantification of HIV-1 in semen. AIDS. 1999; 13:823-831.
26. Vernazza PL, Troiani L, Flepp MJ, et al. Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV. AIDS. 2000; 14:117-121.
27. June P, Altman DG, Egger M. Systematic Reviews in Health Care: Meta-Analysis in Context. London, England: BMJ Press; 2001.
28. Cooper H, Hedges LV. The Handbook of Research Synthesis. New York, NY: Russell Sage Foundation; 1994.
29. Lipsey MW, Wilson DB. Practical Meta-analysis. Thousand Oaks, Calif: Sage; 2001.
30. Dilley JW, Woods WJ, McFarland W. Are advances in treatment changing views about high-risk sex? N Engl J Med. 1997;337:501-502.
31. Dilley JW, Woods WJ, Sabatino J, Rinaldi J, Lihatsh T, McFarland W. Availability of combination therapy for HIV. AIDS Care. 2003;15:27-37.
32. Demmer C. Impact of improved treatments on perceptions about HIV and safer sex among inner-city HIV-infected men and women. J Community Health. 2002; 27:63-73.
33. Kelly JA, Otto-Salaj LL, Sikkema KJ, Pinkerton SD, Bloom FR. Implications of HIV treatment advances for behavioral research on AIDS. Health Psychol. 1998; 17:310-319.
34. van der Straten A. The effects of new treatments on sexual risk taking. Focus. 1998;13:5-6.
35. Kravcik S, Victor G, Houston S, et al. Effect of antiretroviral therapy and viral load on the perceived risk of HIV transmission and the need for safer sexual practices. J Acquir Immune Defic Syndr Hum Retrovirol. 1998;19:124-129.
36. Suarez TP, Kelly JA, Pinkerton SD, et al. Influence of a partner's HIV serostatus, use of highly active antiretroviral therapy, and viral load on perceptions of sexual risk behavior in a community sample of men who have sex with men. J Acquir Immune Defic Syndr. 2001;28:471-477.
37. Herlitz CA, Steel JL. Highly active antiretroviral therapy (HAART): awareness and beliefs about infectivity and the influence on sexual behaviourin the general population of Sweden. Eur J Public Health. 2001;11:251-256.
38. Semple SJ, Patterson TL, Grant I. Binge use of methamphetamine among HIV-positive men who have sex with men. AIDS Educ Prev. 2003;15:133-147.
39. Catz SL, Meredith KL, Mundy LM. Women's HIV transmission risk perceptions and behaviors in the era of potent antiretroviral therapies. AIDS Educ Prev. 2001;13:239-251.
40. Desquilbet L, Deveau C, Goujard C, et al. Increase in at-risk sexual behaviour among HIV-1-infected patients followed in the French PRIMO cohort. AIDS. 2002;16:2329-2333.
41. Remien RH, Wagner G, Garballo-Dieguez A, Dolezal C. Who may be engaging in high-risk sex due to medical treatment advances? AIDS. 1998;12:1560-1561.
42. Vanable PA, Ostrow DG, McKiman DJ. Viral load and HIV treatment attitudes as correlates of sexual risk behavior among HIV-positive gay men. J Psychosom Res. 2003;54:263-269.
43. Gwadz M, De Vogli R, Rotheram-Borus MJ, et al. Behavioral practices regarding combination therapies for HIV/AIDS. J Sex Educ Ther. 1999;24:81-88.
44. Kalichman SC, Rompa D, Austin J, Luke W, DiFonzo K. Viral load, perceived infectivity, and unprotected intercourse. J Acquir Immune Defic Syndr. 2001; 28:303-305.
45. Cooper H. Synthesizing Research: A Guide for Literature Reviews. 3rd ed. Thousand Oaks, Calif. Sage; 1998.
46. Dukers NH, Goudsmit J, de Wit JB, Prins M, Weverling GJ, Coutinho RA. Sexual risk behaviour relates to the virological and immunological improvements during highly active antiretroviral therapy in HIV-1 infection. AIDS. 2001;15:369-378.
47. Elford J, Bolding G, Sherr L. High-risk sexual behavior increases among London gay men between 1998 and 2001. AIDS. 2002;16:1537-1544.
48. De Rosa CJ, Marks G. Prevention counseling of HIV-positive men and self-disclosure of serostatus to sex partners. Health Psychol. 1998;17:224-231.
49. Bouhnik AD, Moatti JP, Vlahov D, et al. Highly active antiretroviral treatment does not increase sexual risk behaviour among French HIV infected injecting drug users. J Epidemiol Community Health. 2002; 56:349-353.
50. DiClemente RJ, Funkhouser E, Wingood G, Fawal H, Holmberg SD, Vermund SH. Protease inhibitor combination therapy and decreased condom use among gay men. South Med J. 2002;95:421-425.
51. Huebner DM, Gerend MA. The relation between beliefs about drug treatments for HIV and sexual risk behavior in gay and bisexual men. Ann Behav Med. 2001;23:304-312.
52. Martin DJ, Riopelle D, Steckart MJ, Geshke N, Lin S. Support group participation, HIV viral load and sexual-risk behavior. Am J Health Behav. 2001;25:513-527.
53. International Collaboration on HIV Optimism. HIV treatments optimism among gay men. J Acquir Immune Defic Syndr. 2003;32:545-550.
54. Johnson WD, Semaan S, Hedges LV, Ramirez G, Mullen PD, Sogolow E. A protocol for the analytical aspects of a systematic review of HIV prevention research. J Acquir Immune Defic Syndr. 2002;30(suppl 1):S62-S72.
55. Hedges LV, Vevea JL. Fixed and random effects models in meta-analysis. Psychol Meth. 1998;3:486-504.
56. Kalichman SC, Nachimson D, Cherry C, Williams E. AIDS treatment advances and behavioral prevention setbacks: preliminary assessment of reduced perceived threat of HIV-AIDS. Health Psychol. 1998;17:546-550.
57. Ostrow DE, Fox KJ, Chmiel JS, et al. Attitudes towards highly active antiretroviral therapy are associated with sexual risk taking among HIV-infected and uninfected homosexual men. AIDS. 2002;16:775-780.
58. van der Straten A, Gomez CA, Saul J, Quan J, Padian N. Sexual risk behaviors among heterosexual HIV serodiscordant couples in the era of post-exposure prevention and viral suppressive therapy. AIDS. 2000; 14:F47-F54.
59. Van de Ven P, Kippax S, Knox S, Prestage G, Crawford J. HIV treatments optimism and sexual behaviour among gay men in Sydney and Melbourne. AIDS. 1999;13:2289-2294.
60. Vanable PA, Ostrow DG, McKiman DJ, Taywaditep KJ, Hope BA. Impact of combination therapies on HIV risk perceptions and sexual risk among HIV-positive and HIV-negative gay and bisexual men. Health Psychol. 2000;19:134-145.
61. Sutton AJ, Abrams KR, Jones DR, Sheldon TA, Song F. Methods for Meta-analysis in Medical Research. New York, NY: Wiley; 2000.
62. Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a sample, graphical test. BMJ. 1997;315:629-634.
63. Miller M, Meyer L, Boufassa F, et al. Sexual behavior changes and protease inhibitor therapy. AIDS. 2000;14:F33-F39.
64. Stephenson JM, Imrie J, Davis MM, et al. Is use of antiretroviral therapy among homosexual men associated with increased risk of transmission of HIV infection? Sex Transm Infect. 2003;79:7-10.
65. Wolf K, Young J, Rickenbach M, et al. Prevalence of unsafe sexual behavior among HIV-infected individuals: the Swiss HIV Cohort Study. J Acquir Immune Defic Syndr. 2003;33:494-499.
66. Scheer S, Chu PL, Klausner JD, Katz MH, Schwarcz SK. Effect of highly active antiretroviral therapy on diagnoses of sexually transmitted diseases in people with AIDS. Lancet 2001;357:432-435.
67. Vlahov D, Safaien M, Lai S, et al. Sexual and drug risk-related behaviours after initiating highly active antiretroviral therapy among injection drug users. AIDS. 2001;15:2311-2316.
68. Wilson TE, Minkoff H. Condom use consistency associated with beliefs regarding HIV disease transmission among women receiving HIV antiretroviral therapy. J Acquir Immune Defic Syndr. 2001;27:289-291.
69. Comulada WS, Swendeman DT, Rotheram-Borus MJ, Mattes KM, Weiss RE. Use of HAART among young people living with HIV. Am J Health Behav. 2003;27:389-400.
70. Kalichman SC. Psychological and social correlates of high-risk sexual behaviour among men and women living with HIV/AIDS. AIDS Care, 1999;11:415-428.
71. Bem DJ. Self perception, an alternative interpreation of cognitive dissonance phenomena. Psychol Rev. 1967;74:183-200.
72. Festinger L. A Theory of Cognitive Dissonance. Evanston, Ill: Row Peterson; 1957.
73. Elford J, Bolding G, Maguire M, Sherr L. Combination therapies for HIV and sexual risk behavior among gay men. J Acquir Immune Defic Syndr. 2000; 23:266-271.
74. Marticka-Tyndale E, Adam BD, Cohen J. Sexual desire and practice among people living with HIV and using combination anti-retroviral therapies. Can J Hum Sex. 2002;11:33-40.