Effect of antiretroviral therapy and viral load on the perceived risk of HIV transmission and the need for safer sexual practices

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology

Volumn 19, Issue 2, 1998, Pages 124-129

  Kravcik, Stephen ^a   Victor, Gary ^a   Houston, Sandra ^b   Sutherland, Donald ^b   Garber, Gary E ^a   Hawley Foss, Nanci ^a   Angel, Jonathan B ^a   Cameron, D William ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b LAB CENTRE FOR DISEASE CONTROL   (Canada)

Author keywords

'Undetectable' viral load Prevention education; Antiretroviral therapy; Behavior knowledge attitudes; Risk factors

Indexed keywords

LAMIVUDINE; ZIDOVUDINE;

ARTICLE; CHEMOPROPHYLAXIS; EDUCATION PROGRAM; FEMALE; HEALTH PROMOTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION CONTROL; INFECTION PREVENTION; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; SEXUAL BEHAVIOR; TREATMENT PLANNING; VIRUS TRANSMISSION;

EID: 0031660470     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199810010-00004     Document Type: Article

References (15)

1. Krieger JN, Coombs RW, Collier AC, et al. Recovery of human immunodeficiency virus type 1 from semen: minimal impact of stage of infection and current antiviral chemotherapy. J infect Dis 1991;163:386-8.
2. Hamed KA, Winters MA, Holodniy M, et al. Detection of human immunodeficiency virus type 1 in semen: effects of disease stage and nucleoside therapy. J Infect Dis 1993;167:798-802.
3. Lennox J, Ellerbrock TV, Palmore M, et al. Effect of Antiretroviral therapy on vaginal HIV RNA level [abstract 727]. IV Conference on Retroviruses and Opportunistic Infections, Washington, DC, 1997.
4. Wiktor S, Ekpini ER, Sibailly TS, et al. The effectiveness of oral zidovudine administered in late pregnancy in lowering plasma and cervicovaginal HIV-1 viral load in HIV-infected pregnant women in Abidjan, Côte D'Ivoire [abstract Tu.C.443]. XI International Conference on AIDS, Vancouver, Canada, 1996.
5. Musicco K, Lazzarin A, Nicolosi A, et al. Antiretroviral treatment of men infected with human immunodeficiency virus type 1 reduces the incidence of heterosexual transmission. Arch Intern Med 1994;154:1971-6.
6. Connor EM, Sperling RS, Gelber R, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. N Engl J Med 1994;331:1173-80.
7. Case control study of HIV seroconversion in health care workers after percutaneous exposure to HIV-infected blood - France, United Kingdom and United States, January 1988-August 1994. MMWR Morb Mortal Wkly Rep 1995;44:929-33.
8. Boswell SL, Mayer KH, Goldstein RS, Tucker L, Xu C, Anderson D. The effect of HIV protease inhibitors on seminal proviral DNA [abstract 202]. IV Conference on Retroviruses and Opportunistic Infections, Washington, DC, 1997.
9. Gupta P, Mellors J, Kingsley L, et al. High viral load in semen of HIV-1 infected men at all stages of disease and its reduction by antiretroviral therapy [abstract 726]. IV Conference on Retroviruses and Opportunistic Infections, Washington, DC, 1997.
10. Cameron DW, Sun E. Markowitz M, et al. Combination use of ritonavir and saquinavir in HIV-infected patients: preliminary safety and activity data [abstract Th.B.934]. XI International Conference on AIDS, Vancouver, Canada, 1996.
11. Hammer SM, Squires KE, Hughes MD, et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less [ACTG 320]. N Engl J Med 1997;337: 725-33.
12. Lifson AR, O'Malley PM, Hessol NA, Buchbinder SP, Cannon L, Rutherford GW. HIV seroconversion in two homosexual men after receptive oral intercourse with ejaculation: implications for counselling concerning safe sexual practices. Am J Public Health 1990; 80:1509-11.
13. Kravcik S, Fillion D, Hawley-Foss N, Gilbert L, Garber G, Cameron B. Increased illicit injection drug use and women with HIV in Ottawa. V Annual Canadian Conference on HIV/AIDS Research [Abstract 361]. Can J Infect Dis 1995;6(Suppl B):46B.
14. Dilley JW, Woods WJ, McFarland W. Are advances in treatment changing views about high-risk sex? [letter]. N Engl J Med 1997; 337:501-2.
15. Henry K, Chinnock BJ, Quinn RP, et al. Concurrent zidovudine levels in semen and serum determined by radioimmunoassay in patients with AIDS or AIDS-related complex. JAMA 1988;259: 3023-6.