Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria

British Journal of Haematology

Volumn 125, Issue 6, 2004, Pages 804-813

  Simak, Jan ^a,d   Holada, Karel ^a,b   Risitano, Antonio M ^c   Zivny, Jan H ^a   Young, Neal S ^c   Vostal, Jaroslav G ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b CHARLES UNIVERSITY   (Czech Republic)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Adhesion molecules; Endothelial cells; Flow cytometry; Paroxysmal nocturnal haemoglobinuria; Sickle cell disease

Indexed keywords

CELL ADHESION MOLECULE; CELL ANTIGEN; LIPOCORTIN 5; PHOSPHATIDYLSERINE;

APLASTIC ANEMIA; ARTICLE; BLOOD ANALYSIS; CELL ASSAY; CELL POPULATION; CELL SPECIFICITY; CLINICAL ARTICLE; COLOR ULTRASOUND FLOWMETRY; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; ERYTHROCYTE MEMBRANE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INFLAMMATORY INFILTRATE; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SICKLE CELL ANEMIA; THROMBOPHLEBITIS; THROMBOSIS; VASCULAR ENDOTHELIUM;

ANEMIA, APLASTIC; ANEMIA, SICKLE CELL; ANTIGENS, CD; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CELL MEMBRANE; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; HEMOGLOBINURIA, PAROXYSMAL; HUMANS;

EID: 3042693914     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2004.04974.x     Document Type: Article

References (37)

1. Abid Hussein, M.N., Meesters, E.W., Osmanovic, N., Romijn, F.P.H.T.M., Nieuwland, R. & Sturk, A. (2003) Antigenic characterization of endothelial cell-derived microparticles and their detection ex vivo. Journal of Thrombosis and Haemostasis, 1, 2434-2443.
2. Berckmans, R.J., Neiuwland, R., Boing, A.N., Romijn, F.P., Hack, C.E. & Sturk, A. (2001) Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. Thrombosis and Haemostasis, 85, 639-646.
3. Bernal-Mizrachi, L., Jy, W., Jimenez, J.J., Pastor, J., Mauro, L.M., Horstman, L.L., de Marchena, E. & Ahn, Y.S. (2003) High levels of circulating endothelial microparticles in patients with acute coronary syndromes. American Heart Journal, 145, 962-970.
4. Boulanger, C.M., Scoazec, A., Ebrahimian, T., Henry, P., Mathieu, E., Tedgui, A. & Mallat, Z. (2001) Circulating microparticles from patients with myocardial infarction cause endothelial dysfunction. Circulation, 104, 2649-2652.
5. Combes, V., Simon, A.C., Grau, G.E., Arnoux, D., Camoin, L., Sabatier, F., Mutin, M., Sanmarco, M., Sampol, J. & Dignat-George, F. (1999) In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant. Journal of Clinical Investigation, 104, 93-102.
6. Dunn, D.E., Tanawattanacharoen, P., Boccuni, P., Nagakura, S., Green, S.W., Kirby, M.R., Kumar, M.S., Rosenfeld, S. & Young, N.S. (1999) Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes. Annals of Internal Medicine, 131, 467-468.
7. Fonsatti, E., Del Vecchio, L., Altomonte, M., Sigalotti, L., Nicotra, M.R., Coral, S., Natali, P.G. & Maio, M. (2001) Endoglin: an accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies. Journal of Cell Physiology, 188, 1-7.
8. Freyssinet, J.-M. (2003) Cellular microparticles: what are they bad or good for? Journal of Thrombosis and Haemostasis, 1, 1655-1662.
9. Hermant, B., Bibert, S., Concord, E., Dublet, B., Weidenhaupt, M., Vernet, T. & Gulino-Debrac, D. (2003) Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrofil transmigration. Journal of Biological Chemistry, 278, 14002-14012.
10. Hugel, B., Socie, G., Vu, T., Toti, F., Gluckman, E., Freyssinet, J.M. & Scrobohaci, M.L. (1999) Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia. Blood, 93, 3451-3456.
11. Jimenez, J.J., Jy, W., Mauro, L.M., Horstman, L.L. & Ahn, Y.S. (2001) Elevated endothelial microparticles in thrombotic thrombocytopenic purpura: findings from brain and renal microvascular cell culture and patients with active disease. British Journal of Haematology, 112, 81-90.
12. Jimenez, J.J., Jy, W., Mauro, L.M., Horstman, L.L., Soderland, C. & Ahn, Y.S. (2003a) Endothelial microparticles released in thrombotic thrombocytopenic purpura express von Willebrand factor and markers of endothelial activation. British Journal of Haematology, 123, 896-902.
13. Jimenez, J.J., Jy, W., Mauro, L.M., Soderland, C., Horstman, L.L. & Ahn, Y.S. (2003b) Endothelial cell release phenotypically and quantitatively distinct microparticles in activation and apoptosis. Thrombosis Research, 109, 175-180.
14. Joop, K., Berckmans, R.J., Nieuwland, R., Berkhout, J., Romijn, F.P., Hack, C.E. & Sturk, A. (2001) Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms. Thrombosis and Haemostasis, 85, 810-820.
15. Maciejewski, J.P., Young, N.S., Yu, M., Anderson, S.M. & Sloand, E.M. (1996) Analysis of the expression of glycosylphosphatidylinositol anchored proteins on platelets from patients with paroxysmal nocturnal hemoglobinuria. Thrombosis Research, 83, 433-447.
16. Maciejewski, P.J., Rivera, C., Kook, H., Dunn, D. & Young, N.S. (2001) Relationship between bone marrow failure syndromes and the presence of glycophosphatidyl inositol-anchored protein-deficient clones. British Journal of Haematology, 115, 1015-1022.
17. Mallat, Z., Hugel, B., Ohan, J., Leseche, G., Freyssinet, J.M. & Tedgui, A. (1999) Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. Circulation, 99, 348-353.
18. Mallat, Z., Benamer, H., Hugel, B., Benessiano, J., Steg, P.G., Freyssinet, J.M. & Tedgui, A. (2000) Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation, 101, 841-843.
19. Minagar, A., Jy, W., Jimenez, J.J., Sheremata, W.A., Mauro, L.M., Mao, W.W., Horstman, L.L. & Ahn, Y.S. (2001) Elevated plasma endothelial microparticles in multiple sclerosis. Neurology, 56, 1319-1324.
20. Mutin, M., Dignat-George, F. & Sampol, J. (1997) Immunologic phenotype of cultured endothelial cells: quantitative analysis of cell surface molecules. Tissue Antigens, 50, 449-458.
21. Nieuwland, R., Berckmans, R.J., McGregor, S., Boing, A.N., Romijn, F.P., Westendorp, R.G., Hack, C.E. & Sturk, A. (2000) Cellular origin and procoagulant properties of microparticles in meningococcal sepsis. Blood, 95, 930-935.
22. Ninomiya, H., Hasegawa, Y., Nagasawa, T. & Abe, T. (1997) Excess soluble urokinase-type plasminogen activator receptor in the plasma of patients with paroxysmal nocturnal hemoglobinuria inhibits cell-associated fibrinolytic activity. International Journal of Hematology, 65, 285-291.
23. Parker, C.J. (2002) Historical aspects of paroxysmal nocturnal haemoglobinuria: 'defining the disease'. British Journal of Haematology, 117, 3-22.
24. Plough, M., Plesner, T., Ronne, E., Ellis, V., Hoyer-Hansen, G., Hansen, N.E. & Dano, K. (1992) The receptor for urokinase-type plasminogen activator is deficient on peripheral blood leukocytes in patients with paroxysmal nocturnal hemoglobinuria. Blood, 79, 1447-1455.
25. Preston, R.A., Jy, W., Jimenez, J.J., Mauro, L.M., Horstman, L.L., Valle, M., Aime, G. & Ahn, Y.S. (2003) Effects of severe hypertension on endothelial and platelet microparticles. Hypertension, 41, 211-217.
26. Rosse, W.F. & Nishimura, J. (2003) Clinical manifestations of paroxysmal nocturnal hemoglobinuria: present state and future problems. International Journal of Hematology, 77, 113-120.
27. Shet, A.S., Aras, O., Gupta, K.M.J.H., Rausch, D.J., Saba, N., Koopmeiners, L., Key, N.S. & Hebbel, R.P. (2003) Sickle blood contains tissue factor positive microparticles derived from endothelial cells and monocytes. Blood, 102, 2678-2683.
28. Simak, J., Holada, K. & Vostal, J.G. (2001) Cellular prion protein (PrPc) is present on endothelial microparticles in plasma of healthy blood donors. Blood, 89, 709a.
29. Simak, J., Holada, K., D'Agnillo, F., Janota, J. & Vostal, J.G. (2002a) Cellular prion protein is expressed on endothelial cells and is released during apoptosis on membrane microparticles found in human plasma. Transfusion, 42, 334-342.
30. Simak, J., Holada, K. & Vostal, J.G. (2002b) Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin. BMC Cell Biology, 3, 1-11.
31. Sims, P.J., Wiedmer, T., Esmon, C.T., Weiss, H.J. & Shattil, S.J. (1989) Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane. Studies in Scott syndrome: an isolated defect in platelet procoagulant activity. Journal of Biological Chemistry, 264, 17049-17057.
32. Steinberg, M.H. & Rodgers, G.P. (2001) Pathophysiology of sickle cell disease: role of cellular and genetic modifiers. Seminars in Hematology, 38, 299-306.
33. Takeda, J., Miyata, T., Kawagoe, K., Lida, Y., Endo, Y., Fujita, T., Takahashi, M., Kitani, T. & Kinoshita, T. (1993) Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell, 73, 703-711.
34. Tomer, A., Harker, L.A., Kasey, S. & Eckman, J.R. (2001) Thrombogenesis in sickle cell disease. Journal of Laboratory and Clinical Medicine, 137, 398-407.
35. Wiedmer, T., Hall, S.E., Ortel, T.L., Kane, W.H., Rosse, W.F. & Sims, P.J. (1993) Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria. Blood, 82, 1192-1196.
36. Wilcox, L.A., Ezzell, J.L., Bernshaw, N.J. & Parker, C.J. (1991) Molecular basis of the enhanced susceptibility of the erythrocytes of paroxysmal nocturnal hemoglobinuria to hemolysis in acidified serum. Blood, 78, 820-829.
37. Young, N.S. & Maciejewski, J.P. (2000) Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes 'why? why? why?'. Journal of Clinical Investigation, 106, 637-641.