Effects of squalene synthase inhibitors on the growth and ultrastructure of Trypanosoma cruzi

International Journal of Antimicrobial Agents

Volumn 24, Issue 1, 2004, Pages 72-78

  Braga, Marina V ^a,c   Urbina, Julio A ^b   De Souza, Wanderley ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Chemotherapy; Ergosterol; Squalene synthase; Sterol biosynthesis inhibitors; Trypanosomatid; Ultrastructure

Indexed keywords

3 (BIPHENYL 4 YL) 3 HYDROXYQUINUCLIDINE; 5 [N [2 BUTENYL 3 (2 METHOXYPHENYL)] N METHYLAMINO] 1 PENTHYLIDENEBIS(PHOSPHONIC ACID); ER 27856; SQUALENE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL VACUOLE; CYTOKINESIS; EPIMASTIGOTE; FLAGELLUM; IC 50; INVAGINATION; MICROTUBULE; MITOCHONDRION; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA CRUZI;

ANIMALS; ENZYME INHIBITORS; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE; MICROSCOPY, ELECTRON; TRYPANOSOMA CRUZI;

EID: 3042646798     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2003.12.009     Document Type: Article

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