Stromal cell-derived factor (SDF) 1-3′A polymorphism may play a role in resistance to HIV-1 infection in seronegative high-risk Thais

Intervirology

Volumn 47, Issue 2, 2004, Pages 87-92

  Tiensiwakul, Pornthep ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

CCR5 32; Human immunodeficiency virus type 1; Polymorphism; Resistance; SDF1 3 A

Indexed keywords

CHEMOKINE; STROMAL CELL DERIVED FACTOR 1; STROMAL CELL DERIVED FACTOR 1 3' A; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD DONOR; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENOTYPE; HIGH RISK POPULATION; HOMOZYGOTE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTITUTION; PROTEIN BLOOD LEVEL; PROTEIN POLYMORPHISM; PROTEIN VARIANT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEROTYPE; VIRUS RESISTANCE;

ADULT; CHEMOKINES, CXC; DNA FINGERPRINTING; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENOTYPE; HIV INFECTIONS; HIV SERONEGATIVITY; HIV-1; HOMOZYGOTE; HUMANS; IMMUNITY, NATURAL; MALE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECEPTORS, CCR5; RECEPTORS, CXCR4; THAILAND; VARIATION (GENETICS);

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; STAPHYLOCOCCUS PHAGE 3A; THAIS;

EID: 3042643027     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000077831     Document Type: Article

References (22)

1. Wu L, Paxton WA, Kassam N, Ruffing N, Rottman JB, Sullivan N, Choe H, Sodroski J, Newman W, Koup RA, Mackay CR: CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J Exp Med 1997;185:1681-1689.
2. Forster R, Kremmer E, Schubel A, Breitfeld D, Kleinschmidt A, Nerl C, Bernhardt G, Lipp M: Intracellular and surface expression of HIV-1 co-receptor CXCR4/fusin on various leukocyte subsets: Rapid internalization and recycling upon activation. J Immunol 1998;160:1522-1531.
3. Reynes J, Portales P, Segondy M, Baillat V, Andre P, Reant B, Avivens O, Couderc G, Beukirane M, Clot J, Eliaou JF, Corbeau P: CD4+ T cell surface CCR5 density as a determining factor of viral load in HIV-1 infected individuals. J Infect Dis 2000;181:927-932.
4. Reynes J, Portales P, Segondy M, Baillat V, Andre P, Avivens O, Picot M, Clot J, Eliaou J, Corbeau P: CD4+ T cell surface CCR5 density as a host factor in HIV-1 disease progression. AIDS 2001;15:1627-1634.
5. Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C: Resistance to HIV-infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996;382:722-725.
6. O'Brien SJ, Moore JP: The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS. Immunol Rev 2000;177:99-111.
7. Martin MP, Carrington M, Dean M, O'Brien SJ, Sheppard HW, Wegner SA, Michael NL: CXCR4 polymorphisms and HIV-1 pathogenesis. AIDS Res Hum Retroviruses 1998;19:430.
8. Winkler C, Modi W, Smith MW, Nelson GW, Wu X, Carrinton M, Dean M, Honjo T, Tashiro K, Yabe D, Buchbinder S, Vittinghoff E, Goedert JJ, O'Brien TR, Jacobson LP, Detels R, Donfield S, Willoughby A, Gomperts E, Vlahov D, Phair J, O'Brien SJ: Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. Science 1998;279:389-393.
9. van Rij RP, Broersen S, Goudsmit J, Coutinho RA, Schuitemaker H: The role of a stromal cell-derived factor-1 chemokine gene variant in the clinical course of HIV-1 infection. AIDS 1998;12:F85-F99.
10. Ikegawa M, Yuan J, Matsumoto K, Herrmann S, Iwamoto A, Nakamura T, Matsushita S, Kimura T, Hondo T, Tashiro K: Elevated plasma stromal cell-derived factor 1 protein level in the progression of HIV type 1 infection/AIDS. AIDS Res Hum Retroviruses 2001;17:587-595.
11. Amara A, Le Gall S, Schwartz O, Salamero J, Montes M, Loetscher P, Baggiolini M, Virelizier J-L, Arenzana-Seisdedos F: HIV coreceptor downregulation as antiviral principle: SDF-1α-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J Exp Med 1997;186:139-146.
12. Trkola A, Paxton WA, Monard SP, Hoxie JA, Siani MA, Thompson DA, Wu L, Mackay CR, Horuk R, Moore JP: Genetic subtype-independent inhibition of human immuno-deficiency virus type 1 replication by CC and CXC chemokines. J Virol 1998;72:394-404.
13. Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier JL, Arenzana-Seisdedos F, Schwartz O, Heard J, Clark-Lewis I, Legler DF, Loetscher M, Baggiolini M, Moser B: The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell line adapted HIV-1. Nature 1996;382:833-835.
14. Bleul CC, Farzan M, Choe H, Parolin C, Clark-Lewis I, Sodroski J, Springer TA: The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996;382:829-832.
15. Llano A, Borretina J, Blanco J, Gutierrez A, Clotel B, Este JA: Stromal-cell-derived factor prevents the emergence of the syncytium-inducing phenotype of HIV-1 in vivo. AIDS 2001;15:1890-1892.
16. Derdeyn CA, Costello C, Kilby JM, Skakianos G, Saag MS, Kaslow R, Bucy RP: Correlation between circulating stromal cell-derived factor 1 levels and CD4+ cell count in human immunodeficiency virus type 1-infected individuals. AIDS Res Hum Retroviruses 1999;15:1063-1071.
17. Tiensiwakul P: Urinary HIV-1 antibody patterns by Western blot assay. Clin Lab Sci 1998; 11:336-368.
18. Huang Y, Paxton WA, Wolinsky SM, Neumann AU, Zhang L, He T, Kang S, Ceradini D, Jin Z, Yazdanbakhsh K, Kunstman K, Erickson D, Dragon E, Landau NR, Phair J, Ho DD, Koup RA: The role of a mutant CCR5 allelle in HIV-1 transmission and disease progression. Nat Med 1996;2:1240-1243.
19. Balotta C, Bagnarelli P, Violin M, Ridolfo AL, Zhou D, Berlusconi A, Corvasce S, Corbellino M, Clementi M, Clerici M, Moroni M, Galli M: Homozygous Δ32 deletion of the CCR-5 chemokine receptor gene in an HIV-1 infected patient. AIDS 1997;11:F67-F71.
20. Tiensiwakul P: Stromal cell-derived factor (SDF)1-3′A polymorphism and sequences in Thais. Asian Pac J Allergy Immunol 2002;20:61-65.
21. Brambilla A, Villa C, Rizzardi G, Veglia F, Ghezzi S, Lazzarin A, Cusini M, Muratori S, Santagostino E, Gringeri A, Louie LG, Sheppard HW, Poli G, Michael NL, Pantaleo G, Vicenzi E: Shorter survival of SDF1-3′A/3′A homozygotes linked to CD4+ T cell decrease in advanced human immunodeficiency virus type 1 infection. J Infect Dis 2000;182:311-315.
22. McCutchan FE, Artenstein AW, Sanders-Buell E, Salminen MO, Carr JK, Mascola JR, Yu XF, Nelson KE, Khamboonruang C, Schmitt D, Kieny MP, McNeil JG, Burke DS: Diversity of the envelope glycoprotein among human immunodeficiency virus type 1 isolates of clade E from Asia and Africa. J Virol 1996;70:3331-3338.