Synthesis of benzoylpyrimidines as antagonists of the corticotropin- releasing factor-1 receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 15, 2004, Pages 3869-3873

  Webb, Thomas R ^a,b   Moran, Terry ^a   Huang, Charles Q ^a   McCarthy, James R ^a   Grigoriadis, Dimitri E ^a   Chen, Chen ^a  

^a Neurocrine Bioscience   (United States)

^b ChemBridge Research Laboratories   (United States)

Author keywords

Antagonist; Benzoylpyrimidine; CRF

Indexed keywords

CORTICOTROPIN RELEASING FACTOR 1 ANTAGONIST; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; STRUCTURE ACTIVITY RELATION;

BENZOATES; CLONING, MOLECULAR; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PYRIMIDINES; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 3042636204     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.05.072     Document Type: Article

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