Decreased expression of mineralocorticoid receptor mRNA in the prefrontal cortex in schizophrenia and bipolar disorder

International Journal of Neuropsychopharmacology

Volumn 7, Issue 2, 2004, Pages 143-153

  Xing, Guo Qiang ^a,b   Russell, Shani ^a,b   Webster, Maree J ^a   Post, Robert M ^b  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Bipolar disorder; MR mRNA; Post mortem brain; Prefrontal cortex; Schizophrenia

Indexed keywords

CORTICOTROPIN; GLUCOCORTICOID RECEPTOR; HORMONE RECEPTOR; HYDROCORTISONE; MINERALOCORTICOID RECEPTOR;

ADULT; ARTICLE; BIPOLAR DISORDER; BRAIN REGION; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IN SITU HYBRIDIZATION; MAJOR DEPRESSION; MALE; MOOD DISORDER; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; SCHIZOPHRENIA; SLOW WAVE SLEEP; STATISTICAL SIGNIFICANCE; STRESS;

ADULT; AGE OF ONSET; AREA UNDER CURVE; AUTORADIOGRAPHY; BIPOLAR DISORDER; CAUSE OF DEATH; DEPRESSIVE DISORDER, MAJOR; DNA, COMPLEMENTARY; FEMALE; FUNCTIONAL LATERALITY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; PREFRONTAL CORTEX; RECEPTORS, MINERALOCORTICOID; RNA, MESSENGER; SCHIZOPHRENIA; SEX CHARACTERISTICS;

EID: 3042585561     PISSN: 14611457     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1461145703004000     Document Type: Article

References (47)

1. Almeida OF, Conde GL, Crochemore C, Demeneix BA, Fischer D, Hassan AH, Meyer M, Holsboer F, Michaelidis TM (2000). Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate. FASEB Journal 14, 779-790.
2. Arvat E, Maccagno B, Giordano R, Pellegrino M, Broglio F, Gianotti L, Maccario M, Camanni F, Ghigo E (2001). Mineralocorticoid receptor blockade by canrenoate increases both spontaneous and stimulated adrenal function in humans. Journal of Clinical Endocrinology and Metabolism 86, 3176-3181.
3. Baghai TC, Schule C, Zwanzger P, Minov C, Holme C, Padberg F, Bidlingmaier M, Strasburger CJ, Rupprecht R (2002). Evaluation of a salivary based combined dexamethasone/CRH test in patients with major depression. Psychoneuroendocrinology 27, 385-399.
4. Benca RM, Obermeyer WH, Thisted RA, Gillin JC (1992). Sleep and psychiatric disorders. A meta-analysis. Archives of General Psychiatry 49, 651-668; discussion 669-670.
5. Born J, Fehm HL (1998). Hypothalamus-pituitary-adrenal activity during human sleep: a coordinating role for the limbic hippocampal system. Experimental and Clinical Endocrinology and Diabetes 106, 153-163.
6. Budziszewska B, Siwanowicz J, Przegalinski E (1994). The effect of chronic treatment with antidepressant drugs on the corticosteroid receptor levels in the rat hippocampus. Polish Journal of Pharmacology 46, 147-152.
7. Chao HM, Choo PH, McEwen BS (1989). Glucocorticoid and mineralocorticoid receptor mRNA expression in rat brain. Neuroendocrinology 50, 365-371.
8. De Kloet ER, Vreugdenhil E, Oitzl MS, Joels M (1998). Brain corticosteroid receptor balance in health and disease. Endocrine Reviews 19, 269-301.
9. Dijkstra I, Tilders FJ, Aguilera G, Kiss A, Rabadan-Diehl C, Barden N, Karanth S, Holsboer F, Reul JM (1998). Reduced activity of hypothalamic corticotropin-releasing hormone neurons in transgenic mice with impaired glucocorticoid receptor function. Journal of Neuroscience 18, 3909-3918.
10. Diorio D, Viau V, Meaney MJ (1993). The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. Journal of Neuroscience 13, 3839-3847.
11. Elman I, Adler CM, Malhotra AK, Bir C, Pickar D, Breier A (1998). Effect of acute metabolic stress on pituitary-adrenal axis activation in patients with schizophrenia. American Journal of Psychiatry 155, 979-981.
12. Gass P, Kretz O, Wolfer DP, Berger S, Tronche F, Reichardt HM, Kellendonk C, Lipp HP, Schmid W, Schutz G (2000). Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice. EMBO Reports 1, 447-451.
13. Gass P, Reichardt HM, Strekalova T, Henn F, Tronche F (2001). Mice with targeted mutations of glucocorticoid and mineralocorticoid receptors: Models for depression and anxiety? Physiology and Behavior 73, 811-825.
14. Gesing A, Bilang-Bleuel A, Droste SK, Linthorst AC, Holsboer F, Reul JM (2001). Psychological stress increases hippocampal mineralocorticoid receptor levels: involvement of corticotropin-releasing hormone. Journal of Neuroscience 21, 4822-4829.
15. Godwin CD, Greenberg LB, Shukla S (1984). Consistent dexamethasone suppression test results with mania and depression in bipolar illness. American Journal of Psychiatry 141, 1263-1265.
16. Herman JP, Cullinan WE (1997). Neurocircuitry of stress: central control of the hypothalamo-pituitary-adrenocortical axis. Trends in Neuroscience 20, 78-84.
17. Hoffmann R, Hendrickse W, Rush AJ, Armitage R (2000). Slow-wave activity during non-REM sleep in men with schizophrenia and major depressive disorders. Psychiatry Research 95, 215-225.
18. Jarskog LF, Gilmore JH, Selinger ES, Lieberman JA (2000). Cortical bcl-2 protein expression and apoptotic regulation in schizophrenia. Biological Psychiatry 48, 641-650.
19. Kalinyak JE, Bradshaw JG, Perlman AJ (1992). The role of development and adrenal steroids in the regulation of the mineralocorticoid receptor messenger RNA. Hormone and Metabolic Research 24, 106-109.
20. Lopez JF, Chalmers DT, Little KY, Watson SJ (1998). A.E. Bennett Research Award. Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: implications for the neurobiology of depression. Biological Psychiatry 43, 547-573.
21. Mizoguchi K, Ishige A, Aburada M, Tabira T (2003). Chronic stress attenuates glucocorticoid negative feedback: involvement of the prefrontal cortex and hippocampus. Neuroscience 119, 887-897.
22. Muck-Seler D, Pivac N, Jakovljevic M, Brzovic Z (1999). Platelet serotonin, plasma cortisol, and dexamethasone suppression test in schizophrenic patients. Biological Psychiatry 45, 1433-1439.
23. O'Donnell D, Larocque S, Seckl JR, Meaney MJ (1994). Postnatal handling alters glucocorticoid, but not mineralocorticoid messenger RNA expression in the hippocampus of adult rats. Brain Research Molecular Brain Research 26, 242-248.
24. Patel PD, Lopez JF, Lyons DM, Burke S, Wallace M, Schatzberg AF (2000). Glucocorticoid and mineralocorticoid receptor mRNA expression in squirrel monkey brain. Journal of Psychiatric Research 34, 383-392.
25. Rajkowska G, Goldman-Rakic P (1995). Cytoarchitectonic definition of prefrontal areas in the normal human cortex: I. Remapping of areas 9 and 46 using quantitative criteria. Cerebral Cortex 5, 307-322.
26. Rajkowska G, Halaris A, Selemon LD (2001). Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biological Psychiatry 49, 741-752.
27. Rajkowska G, Miguel-Hidalgo JJ, Wei J, Dilley G, Pittman SD, Meltzer HY, Overholser JC, Roth BL, Stockmeier CA (1999). Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biological Psychiatry 45, 1085-1098.
28. Rajkowska G, Selemon LD, Goldman-Rakic PS (1998). Neuronal and glial somal size in the prefrontal cortex: a postmortem morphometric study of schizophrenia and Huntington disease. Archives of General Psychiatry 55, 215-224.
29. Reul JM, Stec I, Soder M, Holsboer F (1993). Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system. Endocrinology 133, 312-320.
30. Rybakowski JK, Twardowska K (1999). The dexamethasone/corticotropin- releasing hormone test in depression in bipolar and unipolar affective illness. Journal of Psychiatric Research 33, 363-370.
31. Sanchez MM, Young LJ, Plotsky PM, Insel TR (2000). Distribution of corticosteroid receptors in the rhesus brain: relative absence of glucocorticoid receptors in the hippocampal formation. Journal of Neuroscience 20, 4657-4668.
32. Schmider J, Lammers CH, Gotthardt U, Dettling M, Holsboer F, Heuser IJ (1995). Combined dexamethasone/corticotropin-releasing hormone test in acute and remitted manic patients, in acute depression, and in normal controls: I. Biological Psychiatry 38, 797-802.
33. Seckl JR, Fink G (1992). Antidepressants increase glucocorticoid and mineralocorticoid receptor mRNA expression in rat hippocampus in vivo. Neuroendocrinology 55, 621-626.
34. Semba J, Watanabe H, Suhara T, Akanuma N (2000). Chronic lithium chloride injection increases glucocorticoid receptor but not mineralocorticoid receptor mRNA expression in rat brain. Neuroscience Research 38, 313-319.
35. Smythe JW, Murphy D, Timothy C, Costall B (1997). Hippocampal mineralocorticoid, but not glucocorticoid, receptors modulate anxiety-like behavior in rats. Pharmacology, Biochemistry, and Behavior 56, 507-513.
36. Sousa N, Almeida OF (2002). Corticosteroids: sculptors of the hippocampal formation. Reviews in the Neurosciences 13, 59-84.
37. Spencer RL, Kim PJ, Kalman BA, Cole MA (1998). Evidence for mineralocorticoid receptor facilitation of glucocorticoid receptor-dependent regulation of hypothalamic-pituitary-adrenal axis activity. Endocrinology 139, 2718-2726.
38. Swann AC, Stokes PE, Casper R, Secunda SK, Bowden CL, Berman N, Katz MM, Robins E (1992). Hypothalamic-pituitary-adrenocortical function in mixed and pure mania. Acta Psychiatrica Scandinavica 85, 270-274.
39. Tandon R, Mazzara C, DeQuardo J, Craig KA, Meador-Woodruff JH, Goldman R, Greden JF (1991). Dexamethasone suppression test in schizophrenia: relationship to symptomatology, ventricular enlargement, and outcome. Biological Psychiatry 29, 953-964.
40. Torrey EF, Webster M, Knable M, Johnston N, Yolken RH (2000). The Stanley Foundation brain collection and neuropathology consortium. Schizophrenia Research 44, 151-155.
41. Tronche F, Kellendonk C, Kretz O, Gass P, Anlag K, Orban PC, Bock R, Klein R, Schutz G (1999). Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nature Genetics 23, 99-103.
42. van Oers HJ, de Kloet ER, Whelan T, Levine S (1998). Maternal deprivation effect on the infant's neural stress markers is reversed by tactile stimulation and feeding but not by suppressing corticosterone. Journal of Neuroscience 18, 10171-10179.
43. Vazquez DM, van Oers H, Levine S, Akil H (1996). Regulation of glucocorticoid and mineralocorticoid receptor mRNAs in the hippocampus of the maternally deprived infant rat. Brain Research 731, 79-90.
44. Watzka M, Bidlingmaier F, Beyenburg S, Henke RT, Clusmann H, Elger CE, Schramm J, Klingmuller D, Stoffel-Wagner B (2000). Corticosteroid receptor mRNA expression in the brains of patients with epilepsy. Steroids 65, 895-901.
45. Webster MJ, Knable MB, O'Grady J, Orthmann J, Weickert CS (2002). Regional specificity of brain glucocorticoid receptor mRNA alterations in subjects with schizophrenia and mood disorders. Molecular Psychiatry 7, 985-994.
46. Xing G, Russell S, Hough C, O'Grady J, Zhang L, Yang S, Zhang LX, Post R (2002). Decreased prefrontal CaMKII alpha mRNA in bipolar illness. Neuroreport 13, 501-505.
47. Young EA, Lopez JF, Murphy-Weinberg V, Watson S, Akil H (2003). Mineralocorticoid receptor function in major depression. Archives of General Psychiatry 60, 24-28.