Ceramides and glycosphingolipids in maturation process: Leukemic cells as an experimental model

Blood Cells, Molecules, and Diseases

Volumn 33, Issue 1, 2004, Pages 68-76

  Smoleńska Sym, Gabriela ^a   Spychalska, Justyna ^a   Zdebska, Ewa ^a   Woźniak, Jolanta ^a   Traczyk, Zdzisława ^a   Pszenna, Ewa ^a   Maj, Stanisław ^a   Danikiewicz, Witold ^b   Bieńkowski, Tomasz ^b   Kościelak, Jerzy ^a  

^a INSTITUTE OF HEMATOLOGY AND TRANSFUSION MEDICINE   (Poland)

^b INSTITUTE OF ORGANIC CHEMISTRY   (Poland)

Author keywords

AML; Cer; ceramide; Ceramides; CML; galabiosylceramide, Gal 1 4GalCer; galactosylceramide; GalCer; GalGalCer; Ganglioside shedding; Gb3Cer; globotriaosylceramide, Gal 1 4Gal 1 4GlcCer; Glycosphingolipids; Human neutrophil maturation

Indexed keywords

CERAMIDE; CERAMIDE DERIVATIVE; GANGLIOSIDE GM3; GLUCOSYLCERAMIDE; GLYCOSPHINGOLIPID; LACTOSYLCERAMIDE;

APOPTOSIS; ARTICLE; BLOOD; CELL GROWTH; CELL MATURATION; CONTROLLED STUDY; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; MYELOBLAST; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

CASE-CONTROL STUDIES; CELL DIFFERENTIATION; CERAMIDES; G(M3) GANGLIOSIDE; GLYCOSPHINGOLIPIDS; HUMANS; LACTOSYLCERAMIDES; LEUKEMIA, MYELOID; NEUTROPHILS; PLASMA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 3042567546     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2004.04.002     Document Type: Article

References (53)

1. Hakomori S. Structure, organization and function of glycosphingolipids in membrane. Curr. Opin. Hematol. 10:2003;16-24
2. Hakomori S. Glycosylation defining cancer malignancy: new wine in an old bottle. Proc. Natl. Acad. Sci. 99:2002;10231-10233
3. Hakomori S. Cell adhesion/recognition and signal transduction through glycosphingolipid microdomain. Glycoconjugate J. 17:2000;143-151
4. Yamashita T., Wada R., Sasaki T., Deng C., Bierfreund U., Sandhoff K., Proia R.L. A vital role for glycosphingolipid synthesis during development and differentiation. Proc. Natl. Acad. Sci. 96:1999;9142-9147
5. Brown D.A., London E. Structure and function of sphingolipid-and cholesterol-rich membrane rafts. J. Biol. Chem. 275:2000;17221-17224
6. Kasahara K., Sanai Y. Functional roles of glycosphingolipids in signal transduction via lipid rafts. Glycoconjugate J. 17:2000;153-162
7. Simons K., Toomre D. Lipids rafts and signal transduction. Nat. Rev., Mol. Cell Biol. 1:2000;31-39
8. Hakomori S. The glycosynapse. Proc. Natl. Acad. Sci. 99:2002;225-232
9. Nagafuku M., Kabayama K., Daisuke O., Kato A., Tani-ichi S., Shimada Y., Ohno-Iwashita Y., Yamasaki S., Saito T., Iwabuchi K., Hamaoka T., Inokuchi J., Kosugi A. Reduction of glycosphingolipid levels in lipid rafts affects the expression state and function of glycosylphosphatidylinositol-anchored proteins, but does not impair signal transduction via the T cell receptor. J. Biol. Chem. 278:2003;51920-51927
10. Kiguchi K., Henning-Chubb C.B., Huberman E. Glycosphingolipid patterns of peripheral blood lymphocytes, monocytes and granulocytes are cell specific. J. Biochem. 107:1990;8-14
11. Feuk-Lagerstedt E., Samuelsson M., Mosgoeller W., Movitz C., Rosqvist A., Bergstrom J., Larsson T., Steiner M., Prohaska R., Karlsson A. The presence of stomatin in detergent-insoluble domains of neutrophil granule membranes. J. Leukocyte Biol. 72:2002;970-977
12. Iwabuchi K., Nagaoka I. Lactosylceramide-enriched glycosphingolipid signaling domain mediates superoxide generation from human neutrophils. Blood. 100:2002;1454-1464
13. Macher B.A., Lee W.M.F., Westrick M.A. Glycosphingolipids of normal and leukemic human leukocytes. Mol. Cell. Biochem. 47:1982;81-95
14. Nojri H., Takaku T., Tetsuka T., Motoyoshi K., Miura Y., Saito M. Characteristic expression of glycosphingolipid profiles in the biopotential cell differentiation of human promyelocytic leukemia cell line HL-60. Blood. 64:1984;534-541
15. Pertoft H., Hirtenstein M., Kogedal L. Separation of human mononuclear cells (MNC) and polymorphonuclear (PMNC) in cell populations. Reid E. Methodological Surveys, (B) Biochemistry. vol. 9:1979;67-80
16. Smoleñska-Sym G., Zdebska E., Golszewka E., Woźniak J., Duŕyński T., Maj S., Mokras U., Koœcielak J. Contents of total and protein-bound carbohydrates are low in leukemic leukocytes from patients with acute myelogenous leukemia. Acta Biochim. Pol. 45:1998;361-371
17. Saito T., Hakomori S. Quantitative isolation of total glycosphingolipids from animal cells. J. Lipid Res. 12:1971;257-259
18. Zdebska E., Kościelak J. A single-sample method for determination of carbohydrate and protein contents glycoprotein bands separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal. Biochem. 275:1999;171-179
19. Naoi M., Lee Y.C., Roseman S. Rapid and sensitive determination of sphingosine bases and sphingolipids with fluorescamine. Anal. Biochem. 58:1974;571-577
20. Thomas R.L. Jr., Matsko C.M., Lotze M.T., Amoscato A.A. Mass spectrometric identification of increased C16 ceramide levels during apoptosis. J. Biol. Chem. 43:1999;30580-30588
21. Metelmann W., Muthing J., Peter-Katalinic J. Nano-electrospray ionization quadrupole time-of-flight tandem mass spectrometric analysis of a ganglioside mixture from human granulocytes. Rapid Commun. Mass Spectrom. 14:2000;543-550
22. Lichtman M.A. The stem cell in the pathogenesis and treatment of myelogenous leukemia: a perspective. Leukemia. 15:2001;1489-1494
23. Symington F.W., Murray W.A., Bearman S.I., Hakomori S. Intracellular localization of lactosylceramide, the major human neutrophil glycosphingolipid. J. Biol. Chem. 23:1987;11356-11363
24. Kniep B., Skubitz K.M. Subcellular localization of glycosphingolipids in human neutrophils. J. Leukocyte Biol. 63:1998;83-88
25. Symington F.W. CDw17: a neutrophil glycolipid antigen regulated by activation. J. Immunol. 142:1989;2784-2790
26. Lund-Johansen F., Olweus J., Horejsi V., Skubitz K.M., Thompson J.S., Vilella R., Symington F.W. Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65). J. Immunol. 148:1992;3221-3229
27. Arai T., Bhunia A.K., Chatterjee S., Bulkley G.B. Lactosylceramide stimulates human neutrophils to upregulate Mac-1, adhere to endothelium, and generate reactive oxygen metabolites in vitro. Circ. Res. 82:1998;540-547
28. Borregaard N., Kjeldsen L., Sengelov H. Mobilization of granules in neutrophils from patients with myeloproliferative disorders. Eur. J. Haematol. 50:1993;189-199
29. Gasser O., Hess C., Miot S., Deon C., Sanchez J.-C., Schifferli J.A. Characterisation and properties of ectosomes released by human polymorphonuclear neutrophils. Exp. Cell Res. 285:2002;243-257
30. Merritt W.D., Der-Minassian V., Reaman G.H. Increased GD3 ganglioside in plasma of children with T-cell acute lymphoblastic leukemia. Leukemia. 8:1994;816-822
31. Kong Y., Li R., Ladisch S. Natural forms of shed tumor gangliosides. Biochim. Biophys. Acta. 1394:1998;43-56
32. Dolo V., Li R., Dillinger M., Flati S., Manela J., Taylor B., Pavan A., Ladisch S. Enrichment and localization of ganglioside GD3 and caveolin-1 shed tumor cell membrane vesicles. Biochim. Biophys. Acta. 1486:2000;265-274
33. Prinetti A., Basso L., Appierto V., Villani M.G., Valesecchi M., Loberto N., Prioni S., Chigorno V., Cavadini E., Formelli F., Sonnino S. Altered sphingolipid metabolism N-(4-hydroxyphenyl)-retinamide-resistant A2780 human ovarian carcinoma cells. J. Biol. Chem. 278:2003;5574-5583
34. Plo I., Lehne G., Beckstrom K.J., Maestre N., Bettaieb A., Laurent G., Lautier D. Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells. Mol. Pharmacol. 62:2002;304-312
35. Lavie Y., Fiucci G., Liscovitch M. Up-regulation of caveolae and caveolar constituents in multidrug-resistant cancer cells. J. Biol. Chem. 273:1998;32380-32383
36. Lavie Y., Fiucci G., Czarny M., Liscovitch M. Changes in membrane microdomains and caveolae constituents in multidrug-resistant cancer cells. Lipids. 34:1999;557-563. (suppl.)
37. Demeule M., Jodoin J., Gingras D., Beliveau R. P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries. FEBS Lett. 466:2000;219-224
38. Lavie Y., Cao H., Bursten S.L., Giuliano A.E., Cabot M.C. Accumulation of glucosylceramides in multidrug-resistant cancer cells. J. Biol. Chem. 271:1996;19530-19536
39. Liu Y.Y., Han T.Y., Giuliano A.E., Cabot M.C. Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells. J. Biol. Chem. 274:1999;1140-1146
40. Liu Y.Y., Han T.Y., Giuliano A.E., Cabot M.C. Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J. 15:2001;719-730
41. Iwabuchi K., Handa K., Hakomori S. Separation of "glycosphingolipid signaling domain" from caveolin-containing membrane fraction in mouse melanoma B16 cells and its role in cell adhesion coupled with signaling. J. Biol. Chem. 273:1998;33766-33773
42. Liscovitch M., Lavie Y. Multidrud resistance: a role for cholesterol efflux pathways? Trends Biochem. Sci. 25:2000;530-534
43. Lavie Y., Liscovitch M. Changes in lipid and protein constituents of rafts and caveolae in multidrug resistant cancer cells and their functional consequences. Glycoconjugate J. 17:2000;253-259
44. Lavie Y., Fiucci G., Liscovitch M. Upregulation of caveolin in multidrug resistant cancer cells: functional implications. Adv. Drug Delivery Rev. 49:2001;317-323
45. Van der Kolk D.M., de Vries E.G.E., Noordhoek L., van den Berg E., van der Pol M.A., Muller M., Vellenga E. Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia. Leukemia. 15:2001;1544-1553
46. McKallip R., Li R., Ladisch S. Tumor gangliosides inhibit the tumor-specific immune response. J. Immunol. 163:1999;3718-3726
47. Wang X., Sun P., O'Gorman M., Tai T., Paller A.S. Epidermal growth factor receptor glycosylation for ganglioside GM3 binding and GM3-mediated suppression of activation. Glycobiology. 11:2001;515-522
48. Kalka D., Reitzenstein C., Kopitz J., Cantz M. The plasma membrane ganglioside sialidase cofractionates with markers of lipid rafts. Biochem. Biophys. Res. Commun. 283:2001;989-993
49. Kakugawa Y., Wada T., Yamaguchi K., Yamanami H., Ouchi K., Sato I., Miyagi T. Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression. Proc. Natl. Acad. Sci. 99:2002;10718-10723
50. Spychalska J., Smoleñska-Sym G., Zdebska E., Woźniak J., Kościelak J. Quantitative analysis of LacCer/CDw17 in human myelogenous leukaemic cells. Cell. Mol. Biol. Lett. 8:2003;911-917
51. Radin N.S. Killing cancer cells by poly-drug elevation of ceramide levels. A hypothesis whose time is come? Eur. J. Biochem. 268:2001;193-204
52. Ruvolo P.P. Ceramide regulates cellular homeostasis via diverse stress signaling pathways. Leukemia. 15:2001;1153-1160
53. Sietsma H., Veldman R.J., Kok J.W. The involvement of sphingolipids in multidrug resistance. J. Membr. Biol. 181:2001;153