CTLA-4 gene polymorphism and its association with Graves' disease in the Lebanese population

European Journal of Immunogenetics

Volumn 31, Issue 3, 2004, Pages 141-143

  Nakkash Chmaisse, H ^a   Makki, R F ^a   Abdelhamid, E ^a   Fakhoury, H ^b   Salti, N N ^c   Salti, I ^c  

^a BEIRUT ARAB UNIVERSITY   (Lebanon)

^b KING SAUD BIN ABDULAZIZ UNIVERSITY FOR HEALTH SCIENCES   (Saudi Arabia)

^c AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4;

ARTICLE; CHROMOSOME 2Q; CLINICAL ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC MARKER; GENETIC POLYMORPHISM; GRAVES DISEASE; HUMAN; IMMUNE RESPONSE GENE; IMMUNOGENETICS; IMMUNOPATHOLOGY; LEBANON; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STATISTICAL SIGNIFICANCE;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; CASE-CONTROL STUDIES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GRAVES DISEASE; LEBANON; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 3042541535     PISSN: 09607420     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2370.2004.00455.x     Document Type: Article

References (25)

1. Awata, T., Kurihara, S., Litaka, M., Takei, S., Inoue, I., Fshii, C., Negishi, K. & Izumida, T. (1998) Association of CTLA-4 gene A-G polymorphism (IDDM12 locus) with acute-onset and insulin depleted IDDM as well as autoimmune thyroid disease (Graves' disease and Hasimoto's thyroditis) in a Japanese population. Diabetes, 47, 128.
2. Barton, A., Myerscough, A., Jhon, S., Gonzalez-Gay, M., Ollier, W. & Worthington, J. (2000) A single nucleotide polymorphism inexon 1 of cytotoxic T-lymphocyte-associated-4 (CTLA-4) is not associated with rheumatoid arthritis. Rheumatology, 39, 63.
3. Bech, K., Andersen, V. & Madsen, S.N. (1982) In vitro lymphocyte proliferation in response to polyclonal activators and microbial antigens and production of immunoglobulins stimulating thyroid adenylate cyclase in Graves' disease. Acta Endocrinologica, 108, 252.
4. Bednarczuk, T., Hiromatsu, Y., Funkutani, T., Tazdzewzki, K., Miskiiewicz, P., Osikowska, M. & Nauman, J. (2003) Association of cytotoxic T-lymphocyte-associated antigen (CTLA-4) gene polymorphism and non-gene factors with Graves' ophthalmopathy in European and Japanese populations. European Journal of Endocrinology, 148, 13.
5. Braun, J., Donner, H., Siegmund, T., Walfish, P.G., Usadel, K.H. & Badenhoop, K. (1998) CTLA-4 promoter variants in patients with Graves' disease and Hashimoto's thyroiditis. Tissue Antigen, 51, 563.
6. Collins, J. & Gough, S. (2002) Autoimmunity in thyroid disease. European Journal of Nucleic Medical Molecular Imaging, 29 (Suppl. 2), 5417.
7. Donner, H., Braun, J., Seild, C., Rau, H., Finke, R., Ventz, M., Walfish, P.G. & Usadet, K.H. (1997a) Codon 17 polymorphism of the cytotoxic T lymphocyte antigen 4 gene in Hashimoto's thyroiditis and Addison's disease. Journal of Clinical Endocrinology and Metabolism, 82, 4130.
8. Donner, H., Rau, H., Walfish, P.G. et al. (1997b) CTLA-4 alanine confers genetic susceptibility to Graves' disease and type I diabetes mellitus. Journal of Clinical Endocrinology and Metabolism, 82, 143.
9. Hadj Kacem, H., Bellassoued, M., Bougacha-Elleuch, N. & Abid & Ayadi, H. (2001) CTLA-4 gene polymorphism in Tunisian patients with Graves' disease. Clinical Immunology, 101, 361.
10. Harbo, H.F., Celius, E.G., Vartadal, F. & Spurkland, A. (1999) CTLA-4 promoter and exon 1 dimorphisms in multiple sclerosis. Tissue Antigens, 53, 106.
11. Harper, K., Balzano, C., Rouvier, E., Mattel, M.G., Luciani, M.F. & Goldstein, P. (1991) CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure and chromosomal location. Journal of Immunology, 147, 1037.
12. Heward, J. & Gough, S. (1997) Genetic susceptibility to the development of autoimmune disease. Clinical Science, 93, 479.
13. Heward, J.M., Allahabadia, A., Armitage, M. et al. (1999) The development of Graves' disease and the CTLA-4 gene on chromosome 2q33. Journal of Clinical Endocrinology and Metabolism, 84, 2398.
14. Kinjo, Y., Takasu, N., Komiya, I., Tomoyose, T., Takara, M., Koukishimajiri, Y., Yabiku, K. & Yoshimura, H. (2002) Remission of Graves' hyperthyrodism and A/G polymorphism at position 49 in exon 1 of cytotoxic T lymphocyte-associated molecule-4 gene. Journal of Clinical Endocrinology and Metabolism, 87, 2593.
15. Kosta, K., Watson, P.F. & Weetman, A.P. (1997) A CTLA-4 gene polymorphism is associated with both Graves' disease and autoimmune hypothyroidism. Clinical Endocrinology (Oxf), 46, 551.
16. Mein, C.A., Espositol, L., Dunn, M.G. et al. (1998) A search for type I diabetes susceptibility genes with intermediate effect in families from the UK. Nature Genetics, 19, 213.
17. Nistico, L., Buzzetti, R., Pritchard, L.E. et al. (1996) The CTLA-4 region of chromosome 2q33 is linked to and associated with type I diabetes. Human Molecular Genetics, 5, 1075.
18. Oosterwegel, M.A., Greenwald, R.J., Mandelbrot, D.A., Lorsbach, R.B. & Sharpe, A.H. (1999) CTLA-4 and T-cell activation. Current Opinions in Immunology, 11, 294.
19. Philippou, G. & McGregor. A.M. (1980) The aetiology of Graves' disease: what is the genetic contribution? Clinical Endocrinology, 48, 393.
20. Tsuyoshi, K., Yoshikuni, S., Cyprian, A.G. et al. (2000) CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease. Journal of Immunology, 165, 6606.
21. Ueda, H., Howson, J.M., Esposito, L. et al. (2003) Association of the T-cell regulatory gene CTLA-4 with susceptibility to autoimmune disease. Nature, 423, 506.
22. Van der Auwera, B.S., Vandewalle, C.L., Schuit, F.C., Winnock, F., de Leeuw, L.H., Van Imschoot, S., Lamberigts, G. & Gorus, F.K. (1997). CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. Clinical and Experimental Immunology, 110, 98.
23. Weetman, A.P. & McGregor, A.M. (1994) Autoimmune thyroid disease: further development in our understanding. Endocrine Reviews, 15, 788.
24. Yanagawa, T., Hidaka, Y., Guimares, V., Soliman, M. & DeGroot, L.J. (1995) CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population. Journal of Clinical Endocrinology and Metabolism, 80, 41.
25. Zaletel, K., Krhin, B., Gaberscek, S., Pirnat, E. & Hojeker, S. (2002) The influence of exon 1 polymorphism of the cytotoxic T lymphocyte antigen 4 gene on thyroid antibody production in patients with newly diagnosed Graves' disease. Thyroid, 12, 373.