Association of cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) gene polymorphism and non-genetic factors with Graves' ophthalmopathy in European and Japanese populations

European Journal of Endocrinology

Volumn 148, Issue 1, 2003, Pages 13-18

  Bednarczuk, Tomasz ^a   Hiromatsu, Yuji ^b   Fukutani, Tomoka ^b   Jazdzewski, Krystian ^a   Miskiewicz, Piotr ^c   Osikowska, Maria ^c   Nauman, Janusz ^a,c  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4;

ADOLESCENT; ADULT; AGE; AGED; ALLELE; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE SEVERITY; ENVIRONMENTAL FACTOR; EUROPE; FEMALE; GENDER; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; GRAVES DISEASE; HEREDITY; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; ONSET AGE; POPULATION GENETICS; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; ASIAN CONTINENTAL ANCESTRY GROUP; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GRAVES DISEASE; HUMANS; IMMUNOCONJUGATES; JAPAN; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SEX DISTRIBUTION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0037262497     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1480013     Document Type: Article

References (34)

1. Weetman AP. Graves' disease. New England Journal of Medicine 2000 26 1236-1248.
2. Burch HB & Wartofsky L. Graves' ophthalmopathy: current concepts regarding pathogenesis and management. Endocrine Reviews 1993 14 747-793.
3. Gerding MN, Terwee CB, Dekker FW, Koornneef L, Prummel MF & Wiersinga WM. Quality of life in patients with Graves' ophthalmopathy is markedly decreased: measurement by the medical outcomes study instrument. Thyroid 1997 7 885-889.
4. Bartalena L, Marcocci C & Pinchera A. Graves' ophthalmopathy: a preventable disease? European Journal of Endocrinology 2002 146 457-461.
5. Hagg E & Asplund K. Is endocrine ophthalmopathy related to smoking? British Medical Journal 1987 295 634-635.
6. Bartalena L, Martino E, Marcocci C, Bogazzi F, Panicucci M, Velluzzi F et al. More on smoking habits and Graves' ophthalmopathy. Journal of Endocrinological Investigation 1989 12 733-737.
7. Prummel MF & Wiersinga WM. Smoking and risk of Graves' disease. Journal of the American Medical Association 1993 269 479-482.
8. Perros P, Crombie AL, Matthews JNS & Kendall-Taylor P. Age and gender influence the severity of thyroid-associated ophthalmopathy. Clinical Endocrinology 1993 38 367-372.
9. Bartalena L, Marcocci C, Bogazzi F, Manetti L, Tanda ML, Dell'Unto E et al. Relation between therapy for hyperthyroidism and the course of Graves' ophthalmopathy. New England Journal of Medicine 1998 338 73-78.
10. Tellez M, Cooper J & Edmonds C. Graves' ophthalmopathy in relation to cigarette smoking and ethnic origin. Clinical Endocrinology 1992 36 291-294.
11. Vaidya B, Imrie H, Perros P, Dickinson J, McCarthy MI, Kendall-Taylor P & Pearce SHS. Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism confers susceptibility to thyroid-associated orbitopathy. Lancet 1999 354 743-744.
12. Buzzetti R, Nistico L, Signore A & Cascino I. CTLA-4 and HLA gene susceptibility to thyroid-associated orbitopathy. Lancet 1999 354 1824.
13. Kinjo Y, Takasu N, Komiya I, Tomoyose T, Takara M, Kouki T et al. Remission of Graves' hyperthyroidism and a/g polymorphism at position 49 in exon 1 of cytotoxic T lymphocyte-associated molecule-4 gene. Journal of Clinical Endocrinology and Metabolism 2002 87 2593-2596.
14. Badenhoop K, Donner H, Braun J, Siegmund T, Rau H & Usadel KH. Genetic markers in diagnosis and prediction of relapse in Graves' disease. Experimental and Clinical Endocrinology and Diabetes 1996 104 (Suppl 4) 98-100.
15. Kotsa K, Watson PF & Weetman AP The CTLA-4 gene polymorphism is associated with both Graves' disease and autoimmune hypothyroidism. Clinical Endocrinology 1997 46 551-554.
16. Villanueva R, Inzerillo AM, Tomer Y, Barbesino G, Meltzer M, Concepcion ES et al. Limited genetic susceptibility to severe Graves' ophthalmopathy: no role for CTLA-4 but evidence for an environmental etiology. Thyroid 2000 10 791-798.
17. Allahabadia A, Heward JM, Nithiyananthan R, Gibson SM, Reuser TT, Dodson PM et al. MHC class II region, CTLA4 gene, and ophthalmopathy in patients with Graves' disease. Lancet 2001 358 984-985.
18. Villanueva R, Tomer Y, Greenberg DA, Mao C, Concepcion ES, Tucci S et al. Autoimmune thyroid disease susceptibility loci in a large Chinese family. Clinical Endocrinology 2002 56 45-51.
19. Werner SC. Modification of the classification of the eye changes of Graves' disease: recommendations of the Ad Hoc Committee of the American Thyroid Association. Journal of Clinical Endocrinology and Metabolism 1977 44 203-204.
20. Woolf B. On estimating the relationship between blood group and disease. Annals of Human Genetics 1955 19 251-253.
21. Heufelder AE. Pathogenesis of ophthalmopathy in autoimmune thyroid disease. Reviews in Endocrine and Metabolic Disorders 2000 1 87-95.
22. Bednarczuk T, Hiromatsu Y, Inoue Y, Yamamoto K, Wall JR & Nauman J. T-cell-mediated immunity in thyroid-associated ophthalmopathy. Thyroid 2002 12 209-215.
23. Kouki T, Sawai Y, Gardine CA, Fisfalen ME, Alegre ML & DeGroot LJ. CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease. Journal of Immunology 2000 165 6606-6611.
24. Yanagawa T, Taniyama M, Enomoto S, Gomi K, Maruyama H, Ban Y & Saruta T. CTLA4 gene polymorphism confers susceptibility to Graves' disease in Japanese. Thyroid 1997 7 843-846.
25. Donner H, Rau H, Walfish PG, Braun J, Siegmund T Finke R et al. CTLA-4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. Journal of Clinical Endocrinology and Metabolism 1997 82 143-146.
26. Heward JM, Allahabadia A, Armitage M, Hattersley A, Dodson PM, Macleod K et al. The development of Graves' disease and the CTLA-4 gene on chromosome 2q33. Journal of Clinical Endocrinology and Metabolism 1999 84 2398-2400.
27. Vaidya B, Imrie H, Perros P, Young ET, Kelly WF, Carr D et al. The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus. Human Molecular Genetics 1999 8 1195-1199.
28. Brix TH, Kyvik KO, Christensen K & Hegedus L. Evidence for a major role of heredity in Graves' disease: a population-based study of two Danish twin cohorts. Journal of Clinical Endocrinology and Metabolism 2001 86 930-934.
29. Tomer Y, Greenberg DA, Concepcion E, Ban Y & Davies TF. Thyroglobulin is a thyroid specific gene for the familial autoimmune thyroid diseases. Journal of Clinical Endocrinology and Metabolism 2002 87 404-407.
30. Siegmund T, Usadel KH, Donner H, Braun J, Walfish PG & Badenhoop K. Interferon-gamma gene microsatellite polymorphisms in patients with Graves' disease. Thyroid 1998 8 1013-1017.
31. Farid NR & Balazs C. The genetics of thyroid associated ophthalmopathy. Thyroid 1998 8 407-409.
32. Kamizono S, Hiromatsu Y, Seki N, Bednarczuk T, Matsumoto H, Kimura A & Itoh K. A polymorphism of the 5′ flanking region of tumour necrosis factor a gene is associated with thyroid-associated ophthalmopathy in Japanese. Clinical Endocrinology 2000 52 759-764.
33. Muhlberg T, Kirchberger M, Spitzweg C, Herrman F, Heberling HJ & Heufelder AE. Lack of association of Graves' disease with A2 allele of the interleukin-1 receptor antagonist gene in a white European population. European Journal of Endocrinology 1998 138 686-690.
34. Hunt PJ, Marshall SE, Weetman AP, Bell JI, Wass JAH & Welsh KI. Cytokine gene polymorphisms in autoimmune thyroid disease. Journal of Clinical Endocrinology and Metabolism 2000 85 1984-1988.