Identification of temperature-sensitive dnaD mutants of Staphylococcus aureus that are defective in chromosomal DNA replication

Molecular Genetics and Genomics

Volumn 271, Issue 4, 2004, Pages 447-457

  Li, Y ^a   Kurokawa, K ^a   Matsuo, M ^a   Fukuhara, N ^b,c   Murakami, K ^b   Sekimizu, K ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SHIONOGI AND CO LTD   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

DNA repair; DNA replication; DnaD; Gram positive bacteria; Primosomal protein

Indexed keywords

MITOMYCIN C;

AMINO ACID SUBSTITUTION; AMINO ACID SYNTHESIS; ARTICLE; CHROMOSOME REPLICATION; CONTROLLED STUDY; CYTOMETRY; DNA DAMAGE; DNA REPLICATION; GENE IDENTIFICATION; GENE MUTATION; NONHUMAN; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SOUTHERN BLOTTING; STAPHYLOCOCCUS AUREUS; TEMPERATURE MEASUREMENT;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BLOTTING, SOUTHERN; CHROMOSOMES, BACTERIAL; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA, BACTERIAL; DNA-BINDING PROTEINS; FLOW CYTOMETRY; MITOMYCIN; MUTATION; NUCLEIC ACID SYNTHESIS INHIBITORS; PHENOTYPE; STAPHYLOCOCCUS AUREUS; TEMPERATURE;

POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 3042538224     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-004-0996-6     Document Type: Article

References (49)

1. Allen GC Jr, Kornberg A (1991) Fine balance in the regulation of DnaB helicase by DnaC protein in replication in Escherichia coli. J Biol Chem 266:22096-22101
2. Bird LE, Pan H, Soultanas P, Wigley DB (2000) Mapping protein-protein interactions within a stable complex of DNA primase and DnaB helicase from Bacillus stearothermophilus. Biochemistry 39:171-182
3. Bouche JP, Zechel K, Kornberg A (1975) dnaG gene product, a rifampicin-resistant RNA polymerase, initiates the conversion of a single-stranded coliphage DNA to its duplex replicative form. J Biol Chem 250:5995-6001
4. Bramhill D, Kornberg A (1988) Duplex opening by DnaA protein at novel sequences in initiation of replication at the origin of the E. coli chromosome. Cell 52:743-755
5. Bruand C, Ehrlich SD (1995) The Bacillus subtilis dnaI gene is part of the dnaB operon. Microbiology 141:1199-1200
6. Bruand C, Ehrlich SD, Janniere L (1995a) Primosome assembly site in Bacillus subtilis. EMBO J 14:2642-2650
7. Bruand C, Sorokin A, Serror P, Ehrlich SD (1995b) Nucleotide sequence of the Bacillus subtilis dnaD gene. Microbiology 141:321-322
8. Bruand C, Bidnenko V, Ehrlich SD (2001a) Replication mutations differentially enhance RecA-dependent and RecA-independent recombination between tandem repeats in Bacillus subtilis. Mol Microbiol 39:1248-1258
9. Bruand C, Farache M, McGovern S, Ehrlich SD, Polard P (2001b) DnaB, DnaD and DnaI proteins are components of the Bacillus subtilis replication restart primosome. Mol Microbiol 42:245-255
10. Carl PL (1970) Escherichia coli mutants with temperature-sensitive synthesis of DNA. Mol Gen Genet 109:107-122
11. Cox MM, Goodman MF, Kreuzer KN, Sherratt DJ, Sandler SJ, Marians KJ (2000) The importance of repairing stalled replication forks. Nature 404:37-41
12. Ehrlich SD (1977) Replication and expression of plasmids from Staphylococcus aureus in Bacillus subtilis. Proc Natl Acad Sci USA 74:1680-1682
13. Fujimura T, Murakami K (1997) Increase of methicillin resistance in Staphylococcus aureus caused by deletion of a gene whose product is homologous to lytic enzymes. J Bacteriol 179:6294-6301
14. Hiasa H, Marians KJ (1999) Initiation of bidirectional replication at the chromosomal origin is directed by the interaction between helicase and primase. J Biol Chem 274:27244-27248
15. Ichihashi N, Kurokawa K, Matsuo M, Kaito C, Sekimizu K (2003) Inhibitory effects of basic or neutral phospholipid on acidic phospholipid-mediated dissociation of adenine nucleotide bound to DnaA protein, the initiator of chromosomal DNA replication. J Biol Chem 278:28778-28786
16. Imai Y, Ogasawara N, Ishigo-Oka D, Kadoya R, Daito T, Moriya S (2000) Subcellular localization of DNA-initiation proteins of Bacillus subtilis: evidence that chromosome replication begins at either edge of the nucleoids. Mol Microbiol 36:1037-1048
17. Inoue R, Kaito C, Tanabe M, Kamura K, Akimitsu N, Sekimizu K (2001) Genetic identification of two distinct DNA polymerases, DnaE and PolC, that are essential for chromosomal DNA replication in Staphylococcus aureus. Mol Genet Genomics 266:564-571
18. Ishigo-Oka D, Ogasawara N, Moriya S (2001) DnaD protein of Bacillus subtilis interacts with DnaA, the initiator protein of replication. J Bacteriol 183:2148-2150
19. Kaito C, Kurokawa K, Hossain MS, Akimitsu N, Sekimizu K (2002) Isolation and characterization of temperature-sensitive mutants of the Staphylococcus aureus dnaC gene. FEMS Microbiol Lett 210:157-164
20. Karamata D, Gross JD (1970) Isolation and genetic analysis of temperature-sensitive mutants of B. subtilis defective in DNA synthesis. Mol Gen Genet 108:277-287
21. Kelman Z, O'Donnell M (1995) DNA polymerase III holoenzyme: structure and function of a chromosomal replicating machine. Annu Rev Biochem 64:171-200
22. Kogoma T (1997) Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription. Microbiol Mol Biol Rev 61:212-238
23. Kogoma T, Cadwell GW, Barnard KG, Asai T (1996) The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair. J Bacteriol 178:1258-1264
24. Kornberg A, Baker T (1992) DNA Replication. WH Freeman, New York
25. Kowalczykowski SC (2000) Initiation of genetic recombination and recombination-dependent replication. Trends Biochem Sci 25:156-165
26. Kunst F, et al (1997) The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature 390:249-256
27. Kuroda M, et al (2001) Whole genome sequencing of methicillin-resistant Staphylococcus aureus. Lancet 357:1225-1240
28. Lark CA, Riazi J, Lark KG (1978) dnaT, a dominant conditional-lethal mutation affecting DNA replication in Escherichia coli. J Bacteriol 136:1008-1017
29. Lemon KP, Grossman AD (1998) Localization of bacterial DNA polymerase: evidence for a factory model of replication. Science 282:1516-1519
30. Lu YB, Ratnakar PV, Mohanty BK, Bastia D (1996) Direct physical interaction between DnaG primase and DnaB helicase of Escherichia coli is necessary for optimal synthesis of primer RNA. Proc Natl Acad Sci USA 93:12902-12907
31. Marians KJ (2000) PriA-directed replication fork restart in Escherichia coli. Trends Biochem Sci 25:185-189
32. Marsin S, McGovern S, Ehrlich SD, Bruand C, Polard P (2001) Early steps of Bacillus subtilis primosome assembly. J Biol Chem 276:45818-45825
33. Moriya S, Imai Y, Hassan AK, Ogasawara N (1999) Regulation of initiation of Bacillus subtilis chromosome replication. Plasmid 41:17-29
34. Ng JY, Marians KJ (1996) The ordered assembly of the phiX174-type primosome. I. Isolation and identification of intermediate protein-DNA complexes. J Biol Chem 271:15642-15648
35. Ogasawara N, Moriya S, Mazza PG, Yoshikawa H (1986) Nucleotide sequence and organization of dnaB gene and neighbouring genes on the Bacillus subtilis chromosome. Nucleic Acids Res 14:9989-9999
36. Polard P, Marsin S, McGovern S, Velten M, Wigley DB, Ehrlich SD, Bruand C (2002) Restart of DNA replication in Gram-positive bacteria: functional characterisation of the Bacillus subtilis PriA initiator. Nucleic Acids Res 30:1593-1605
37. Schekman R, Weiner JH, Weiner A, Kornberg A (1975) Ten proteins required for conversion of phiX174 single-stranded DNA to duplex form in vitro. Resolution and reconstitution. J Biol Chem 250:5859-5865
38. Sekimizu K, Bramhill D, Kornberg A (1988) Sequential early stages in the in vitro initiation of replication at the origin of the Escherichia coli chromosome. J Biol Chem 263:7124-7130
39. Skarstad K, Wold S (1995) The speed of the Escherichia coli fork in vivo depends on the DnaB:DnaC ratio. Mol Microbiol 17:825-831
40. Skarstad K, Bernander R, Boye E (1995) Analysis of DNA replication in vivo by flow cytometry. Methods Enzymol 262:604-613
41. Soultanas P (2002) A functional interaction between the putative primosomal protein DnaI and the main replicative DNA helicase DnaB in Bacillus. Nucleic Acids Res 30:966-974
42. Tougu K, Peng H, Marians KJ (1994) Identification of a domain of Escherichia coli primase required for functional interaction with the DnaB helicase at the replication fork. J Biol Chem 269:4675-4682
43. Velten M, McGovern S, Marsin S, Ehrlich SD, Noirot P, Polard P (2003) A two-protein strategy for the functional loading of a cellular replicative DNA helicase. Mol Cell 11:1009-1020
44. Wechsler JA (1975) Genetic and phenotypic characterization of dnaC mutations. J Bacteriol 121:594-599
45. Wechsler JA, Gross JD (1971) Escherichia coli mutants temperature-sensitive for DNA synthesis. Mol Gen Genet 113:273-284
46. Wickner S (1977) DNA or RNA priming of bacteriophage G4 DNA synthesis by Escherichia coli dnaG protein. Proc Natl Acad Sci U S A 74:2815-2819
47. Wickner S, Hurwitz J (1974) Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins. Proc Natl Acad Sci USA 71:4120-4124
48. Wu CA, Zechner EL, Marians KJ (1992a) Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size. J Biol Chem 267:4030-4044
49. Wu CA, Zechner EL, Reems JA, McHenry CS, Marians KJ (1992b) Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. V. Primase action regulates the cycle of Okazaki fragment synthesis. J Biol Chem 267:4074-4083