Time-resolved absorption and UV resonance raman spectra reveal stepwise formation of T quaternary contacts in the allosteric pathway of hemoglobin

Journal of Molecular Biology

Volumn 340, Issue 4, 2004, Pages 843-856

  Balakrishnan, Gurusamy ^a   Case, Martin A ^a,b   Pevsner, Alex ^a   Zhao, Xiaojie ^a,c   Tengroth, Charbel ^a,d   McLendon, George L ^a   Spiro, Thomas G ^a  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF VERMONT   (United States)

^c Photonics Industries Inc   (United States)

^d ASTRAZENECA R AND D   (Sweden)

Author keywords

allostery; GNM, Gaussian network model; Hb, hemoglobin; hemoglobin; MCD, magnetic circular dichroism; protein dynamics; resonance Raman; RR, resonance Raman; SVD, singular value decomposition; TA, transient absorption; transient absorption

Indexed keywords

ASPARTIC ACID; HEME; HEMOGLOBIN; TRYPTOPHAN;

ABSORPTION SPECTROSCOPY; ALLOSTERISM; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; HUMAN; HYDROGEN BOND; LASER; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAMAN SPECTROMETRY; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

MUS;

EID: 3042521090     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.05.012     Document Type: Article

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