Molecular switch in signal transduction: Reaction paths of the conformational changes in ras p21

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 22, 1997, Pages 11905-11910

  Ma, Jianpeng ^a   Karplus, Martin ^a,b,c  

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c Harvard ^*  (United States)

Author keywords

Constrained molecular dynamics; GTP; Molecular signals; Phosphate hydrolysis

Indexed keywords

ARGININE; ASPARTIC ACID; GLUTAMIC ACID; GUANOSINE TRIPHOSPHATE; PROTEIN P21; RAF PROTEIN; TYROSINE;

ALPHA HELIX; ARTICLE; CONFORMATIONAL TRANSITION; HYDROGEN BOND; MOLECULAR DYNAMICS; ONCOGENE RAS; PRIORITY JOURNAL; REACTION ANALYSIS; SIGNAL TRANSDUCTION;

COMPUTER SIMULATION; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTO-ONCOGENE PROTEINS P21(RAS); SIGNAL TRANSDUCTION;

EID: 0030711616     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.22.11905     Document Type: Article

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