A systematic framework for the design of reduced-order models for signal transduction pathways from a control theoretic perspective

Computers and Chemical Engineering

Volumn 30, Issue 3, 2006, Pages 437-452

  Maurya, Mano Ram ^a,c   Katare, Santhoji ^a,d   Patkar, Priyan R ^a   Rundell, Ann E ^b   Venkatasubramanian, Venkat ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d FORD MOTOR COMPANY   (United States)

Author keywords

Bistable behavior; Control; Parameter estimation; Reduced order model; Signal transduction

Indexed keywords

AMPLIFICATION; CELLS; FEEDBACK; GENETIC ALGORITHMS; ITERATIVE METHODS; PARAMETER ESTIMATION;

BISTABLE BEHAVIOR; CELL PROLIFERATION; FILTERING DISPLAY STRIKING SIMILARITIES; MITOGEN-ACTIVATED PROTEIN KINASE (MAPK); REDUCED-ORDER MODEL;

METABOLISM;

CONTROL SYSTEM;

EID: 30344478862     PISSN: 00981354     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compchemeng.2005.10.003     Document Type: Article

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