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Bioorganic and Medicinal Chemistry

Volumn 14, Issue 4, 2006, Pages 1058-1062

Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates

(5) Liang, Fu Sen a Brik, Ashraf a Lin, Ying Chuan a Elder, John H a Wong, Chi Huey a

a SCRIPPS RESEARCH INSTITUTE (United States)

Author keywords

Epoxide opening; HIV protease inhibitors; In situ screening; In water

Indexed keywords

AMINE; ENZYME INHIBITOR; EPOXIDE; PROTEIN INHIBITOR; PROTEINASE INHIBITOR; WATER;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; DRUG SCREENING; DRUG SYNTHESIS; MICROTITER PLATE ASSAY; SCREENING;

AMIDES; AMINES; DRUG EVALUATION, PRECLINICAL; EPOXY COMPOUNDS; HIV PROTEASE INHIBITORS; HYDROXYLATION; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; WATER;

EID: 30344449178 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2005.09.026 Document Type: Article

Times cited : (16)

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