Uterus necrosis after radiochemotherapy in two patients with advanced cervical cancer

Strahlentherapie und Onkologie

Volumn 182, Issue 1, 2006, Pages 45-51

  Marnitz, Simone ^a   Köhler, Christhardt ^a   Füller, Jürgen ^b   Hinkelbein, Wolfgang ^a   Schneider, Achim ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

Cervical cancer; Chemoradiation; Necrosis of the uterus

Indexed keywords

ANTIBIOTIC AGENT; C REACTIVE PROTEIN; CISPLATIN; RECOMBINANT ALPHA2A INTERFERON;

ABNORMALLY HIGH SUBSTRATE CONCENTRATION IN BLOOD; ADULT; ADVANCED CANCER; ARTICLE; BACTERIURIA; BLADDER DISEASE; BRACHYTHERAPY; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER PALLIATIVE THERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CASE REPORT; DIARRHEA; EXTERNAL BEAM RADIOTHERAPY; FEMALE; HUMAN; HYSTERECTOMY; LAPAROSCOPY; LEUKOCYTE COUNT; LYMPH NODE IRRADIATION; NAUSEA; PARAAORTIC LYMPH NODE; PELVIS EXENTERATION; PELVIS LYMPH NODE; PELVIS PAIN SYNDROME; PROTEIN BLOOD LEVEL; SALPINGOOOPHORECTOMY; SQUAMOUS CELL CARCINOMA; TISSUE NECROSIS; TREATMENT PLANNING; UTERINE CERVIX CARCINOMA; UTERUS DISEASE;

ADULT; ANTINEOPLASTIC AGENTS; BRACHYTHERAPY; CARCINOMA, SQUAMOUS CELL; CERVIX UTERI; CISPLATIN; COMBINED MODALITY THERAPY; FEMALE; HUMANS; HYSTERECTOMY; IRIDIUM RADIOISOTOPES; LAPAROSCOPY; MIDDLE AGED; NECROSIS; NEOPLASM STAGING; OVARIECTOMY; RADIATION INJURIES; RADIOTHERAPY; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; TIME FACTORS; UTERINE CERVICAL NEOPLASMS; UTERUS;

EID: 30344442121     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00066-006-1455-6     Document Type: Article

References (29)

1. Burman C, Kutcher GJ, Emami B, et al. Fitting of normal tissue tolerance data to an analytic function. Int J Radiat Oncol Biol Phys 1991;21:123-35.
2. Clark BG, Souhami L, Roman TN, et al. The prediction of late rectal complications in patients treated with high dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 1997;38:989-93.
3. Dale E, Hellebust TP, Skjonsberg A, et al. Modeling normal tissue complication probability from repetitive computed tomography scans during fractionated high-dose-rate brachytherapy and external beam radiotherapy of the uterine cervix. Int J Radiat Oncol Biol Phys 2000;47:963-71.
4. D'Souza WD, Ahamad AA, Iyer RB, et al. Feasibility of dose escalation using intensity-modulated radiotherapy in posthysterectomy cervical carcinoma. Int J Radiat Oncol Biol Phys 2005;61:1062-70.
5. Dunst J. Erythropoietin and radiotherapy: a dangerous combination? Strahlenther Onkol 2004;180:133-5.
6. Dunst J, Haensgen G. Simultaneous radiochemotherapy in cervical cancer: recommendations for chemotherapy. Strahlenther Onkol 2001;177:635-40.
7. Eifel P, Levenback C, Wharton JT, et al. Time course and incidence of late complications in patients treated with radiation therapy for FIGO stage IB carcinoma of the uterine cervix. Int J Radiation Oncol Biol Phys 1995;32:1289-300.
8. Heron DE, Gerszten K, Selvaraj RN, et al. Conventional 3D conformal versus intensity-modulated radiotherapy for the adjuvant treatment of gynecologic malignancies: a comparative dosimetric study of dose-volume histograms. Gynecol Oncol 2003;91:39-45.
9. ICRU Report 38. Dose and volume specification for reporting intracavitary therapy in gynecology. Bethesda: International Commission on Radiation Units and Measurements, 1985.
10. Keys HM, Bundy BN, Stehman FB, et al. Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med 1999;340:1154-61.
11. Kirwan JM, Symonds P, Green JA, et al. A systematic review of acute and late toxicity of concomitant chemoradiation for cervical cancer. Radiother Oncol 2003;68:217-26.
12. Landoni F, Maneo A, Colombo A, et al. Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer. Lancet 1997;350:535-40.
13. Mayer A, Nemeskeri C, Petnehazi C, et al. Primary radiotherapy of stage IIA/B-IIIB cervical carcinoma. A comparison of continuous versus sequential regimens. Strahlenther Onkol 2004;180:209-15.
14. Morris M, Eifel PJ, Lu J, et al. Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N Engl J Med 1999;340:1137-43.
15. Nag S, Erickson B, Thomadsen B, et al. The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 2000;48:201-11.
16. Olofsen-van Acht MJ, Quint S, Seven M, et al. Three-dimensional treatment planning for postoperative radiotherapy in patients with node-positive cervical cancer. Comparison between a conventional and a conformal technique. Strahlenther Onkol 1999;175:462-9.
17. Peters WA 3rd, Liu PY, Barrett RJ 2nd, et al. Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol 2000;18:1606-13.
18. Roeske JC, Bonta D, Mell LK, et al. A dosimetric analysis of acute gastrointestinal toxicity in women receiving intensity-modulated whole-pelvic radiation therapy. Radiother Oncol 2003;69:201-7.
19. Roeske JC, Lujan A, Rotmensch J, et al. Intensity-modulated whole pelvic radiation therapy in patients with gynecologic malignancies. Int J Radiat Oncol Biol Phys 2000;48:1613-21.
20. Roeske JC, Mundt AJ, Halpern H, et al. Late rectal sequelae following definitive radiation therapy for carcinoma of the uterine cervix: a dosimetric analysis. Int J Radiat Oncol Biol Phys 1997;37:351-8.
21. Rose PG, Bundy BN, Watkins EB, et al. Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 1999;340:1144-53.
22. Sakata KI, Nagakura H, Oouchi A, et al. High dose rate brachytherapy: results of analyses of late rectal complications. Int J Radiat Oncol Biol Phys 2002;54:1369-76.
23. Strauss HG, Kuhnt T, Laban C, et al. Chemoradiation in cervical cancer with cisplatin and high-dose rate brachytherapy combined with external beam radiotherapy. Results of a phase-II study. Strahlenther Onkol 2002;178:378-85.
24. Thomas GM. Improved treatment for cervical cancer, concurrent chemotherapy and radiotherapy. N Engl J Med 1999;340:1198-9.
25. Tseng CJ, Chang CT, Lai CH, et al. A randomized trial of concurrent chemoradiotherapy versus radiotherapy in advanced carcinoma of the uterine cervix. Gynecol Oncol 1997;66:52-8.
26. Vordermark D, Brown JM. Endogenous markers of tumor hypoxia predictors of clinical radiation resistance? Strahlenther Onkol 2003;179:801-11.
27. Weitmann HD, Gurstorff B, Vaupel P, et al. Oxygenation status of cervical carcinomas before and during spinal anesthesia for application of brachytherapy. Strahlenther Onkol 2003;179:633-40.
28. Whitney CW, Sause W, Bundy BN, et al. Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol 1999;17:1339-48.
29. Wulf J, Popp K, Oppitz U, et al. Positional variability of a tandem applicator system in HDR brachytherapy for primary treatment of cervix cancer. Analysis of the anatomic pelvic position and comparison of the applicator positions during five insertions. Strahlenther Onkol 2004;180:216-24.