OsGAP1 functions as a positive regulator of OsRab11-mediated TGN to PM or vacuole trafficking

Plant and Cell Physiology

Volumn 46, Issue 12, 2005, Pages 2005-2018

  Jae, Bok Heo ^a   Hee, Sun Rho ^a   Se, Won Kim ^a   Sung, Min Hwang ^a   Hyun, Jin Kwon ^a   Min, Yeop Nahm ^a   Woo, Young Bang ^a   Jeong, Dong Bahk ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

OsGAP1; OsRAB11; Pre vacuolar compartment; Trans Golgi network; Vesicular trafficking

Indexed keywords

ALANINE; ARGININE; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PLANT DNA; RAB PROTEIN; RAB11 PROTEIN; VEGETABLE PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL MEMBRANE; CELL VACUOLE; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENE; GENE EXPRESSION REGULATION; GENETICS; HYDROLYSIS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; PROTEIN TRANSPORT; RICE; TRANS GOLGI NETWORK; WESTERN BLOTTING;

ALANINE; AMINO ACID SEQUENCE; ARGININE; BLOTTING, WESTERN; CELL MEMBRANE; DNA, PLANT; GENE EXPRESSION REGULATION, PLANT; GENES, PLANT; GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; HYDROLYSIS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; ORYZA SATIVA; PLANT PROTEINS; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS; TRANS-GOLGI NETWORK; VACUOLES;

ARABIDOPSIS; MAMMALIA; ORYZA SATIVA;

EID: 30344440086     PISSN: 00320781     EISSN: 14719053     Source Type: Journal    
DOI: 10.1093/pcp/pci215     Document Type: Article

References (61)

1. Ahmadian, M.R., Stege, P., Scheffzek, K. and Wittinghofer, A. (1997) Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of ras. Nat. Struct. Biol. 4: 686-689.
2. 2-terminal propeptide-containing vacuolar proteins in Arabidopsis thaliana. J. Cell Biol. 149: 1335-1344.
3. Albert, S. and Gallwitz, D. (1999) Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition. J. Biol. Chem. 274: 33186-33189.
4. Albert, S. and Gallwitz, D. (2000) Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP. J. Biol. Chem. 381: 453-456.
5. Albert, S., Will, E. and Gallwitz, D. (1999) Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases. EMBO J. 18: 5216-5225.
6. Araki, S., Kikuchi, A., Hata, Y., Isomura, M. and Takai, Y. (1990) Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor. J. Biol. Chem. 265: 13007-13015.
7. Baldari, C., Murray, J.A., Ghiara, P., Cesareni, G. and Galeotti, C.L. (1987) A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1 beta in Saccharomyces cerevisiae. EMBO J. 6: 229-234.
8. Barend, H.J., Graaf, de., Cheung, A.Y., Andreyeva, T., Levasseur, K., Kieliszewski, M. and Wu, H.M. (2005) Rab11 GTPase-regulated membrane trafficking is crucial for tip-focused pollen tube growth in tobacco. Plant Cell 17: 2564-2579.
9. Barrett, T. and Xiao, B. (1997) The structure of the GTPase-activating domain from p50rhoGAP. Nature 385: 458-461.
10. Batoko, H., Zheng, H.Q., Hawes, C. and Moore, I. (2000) A Rab1 GTPase is required for transport between the endoplasmic reticulum and Golgi apparatus and for normal Golgi movement in plants. Plant Cell 12: 2201-2218.
11. Benli, M., Doring, F., Robinson, D.G., Yang, X. and Gallwitz, D. (1996) Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast. EMBO J. 15: 6460-6075.
12. Bonza, M.C., Morandini, P., Luoni, L., Geisler, M., Palmgren, M.G. and Michelis, M.I.D. (2000) At-ACA8 encodes a plasma membrane-localized calcium-ATPase of arabidopsis with a calmodulin-binding domain at the N terminus. Plant Physiol. 123: 1495-1505.
13. Chen, W., Feng, Y., Chen, D. and Angela, W.N. (1998) Rab11 is required for trans-Golgi network-to-plasma membrane transport and a preferential target for GDP dissociation inhibitor. Mol. Biol. Cell 9: 3241-3257.
14. Clabecq, A., Henry, J.P. and Darchen, F. (2000) Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP. J. Biol. Chem. 275: 31786-31791
15. Cuif, M.H. (1999) Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome. EMBO J. 18: 1772-1782.
16. 4-binding protein as a member of the GAP1 family. Nature 376: 527-530.
17. +-ATPase isoforms to the plasma membrane. Plant Physiol. 112: 833-844.
18. Diaz, E., Schimmöller, F. and Pfeffer, S.R. (1997) A novel Rab9 effector required for endosome-to-TGN transport. J. Cell Biol. 138: 283-290.
19. Du, L.L. and Novick, P. (2001) Yeast Rab GTPase-activating protein Gyp1p localizes to the Golgi apparatus and is a negative regulator of Ypt1p. Mol. Biol. Cell 12: 1215-1226.
20. Du, L.L., Collins, R.N. and Novick, P.J. (1998) Identification of a Sec4p GTPase-activating protein (GAP) as a novel member of a Rab GAP family. J. Biol. Chem. 273: 3253-3256.
21. Fukui, K., Sasaki, T., Imazumi, K., Matsuura, Y., Nakanishi, H. and Takai, Y. (1997) Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins. J. Biol. Chem. 272: 4655-4658.
22. +-ATPase. Planta 185: 527-537.
23. Hawes, C.R., Brandizzi, F. and Andreeva, A.V. (1999) Endomembranes and vesicle trafficking. Curr. Opin. Plant Biol. 2: 454-461.
24. Hohl, I., Robinson, D.G., Chrispeels, M.J. and Hinz, G. (1996) Transport of storage proteins to the vacuole is mediated by vesicles without a clathrin coat. J. Cell Sci. 109: 2539-2550.
25. Inaba, T., Nagano, Y., Nagasaki, T. and Sasaki, Y. (2002) Distinct localization of two closely related Ypt3/Rab11 proteins on the trafficking pathway in higher plants. J. Biol. Chem. 277: 9183-9188.
26. Jiang, L. and Rogers, J.C. (1998) Integral membrane proteins sorting to vacuoles in plant cells: evidence for two pathways. J. Cell Biol. 143: 1183-1199.
27. Jin, J.B., Kim, Y.A., Kim, S.J., Lee, S.H., Kim, D.H., Cheong, G.W. and Hwang, I. (2001) A new dynamin-like protein, ADL6, is involved in trafficking from the trans-Golgi network to the central vacuole in Arabidopsis. Plant Cell 13: 1511-1526.
28. Jones, S., Richardson, C.J., Litt, R.J. and Segev, N. (1998) Identification of regulators for Ypt1 GTPase nucleotide cycling. Mol. Biol. Cell 9: 2819-2837.
29. Kim, D.H., Eu, Y.J., Yoo, C.M., Kim, Y.W., Pih, K.T., Jin, J.B., Kim, S.J., Stenmark, H. and Hwang, I. (2001) Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells. Plant Cell 13: 287-301.
30. Li, G. and Liang, Z. (2001) Phosphate-binding loop and Rab GTPase iunction: mutations at Ser29 and Ala30 of Rab5 lead to loss-of-function as well as gain-of-function phenotype. Biochem. J. 355: 681-689.
31. Maekawa, M., Li, S., Iwamatsu, A., Morishita, T., Yokota, K., Imai, Y., Kohsaka, S., Nakamura, S. and Hattori, S. (1994) A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions. Mol. Cell. Biol. 14: 6879-6885.
32. Nahm, M.Y., Kim, S.W., Yun, D.J., Lee, S.Y., Cho, M.J. and Bahk, J.D. (2003) Molecular and biochemical analyses of OsRab7, a rice Rab7 homolog. Plant Cell Physiol. 44: 1341-1349.
33. Neuwald, A.F. (1997) A shared domain between a spindle assembly checkpoint protein and Ypt/Rab-specific GTPase activators. Trends Biochem. Sci. 22: 243-244.
34. Novick, P. and Zerial, M. (1997) The diversity of rab proteins in vesicle transport. Curr. Opin. Cell Biol. 9: 496-504.
35. Peranen, J., Auvinen, P., Virta, H., Wepf, R. and Simons, K. (1996) Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts. J. Cell Biol. 135: 153-167.
36. Rak, A., Fedorov, R., Alexandrov, K., Albert, S., Goody, R.S., Gallwitz, D. and Scheidig, A.J. (2000) Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins. EMBO J. 19: 5105-5113.
37. Ren, M., Zeng, J., De Lemos-Chiarandini. C., Rosenfeld, M., Adesnik, M. and Sabatini, D.D. (1996) In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase. Proc. Natl Acad. Sci. USA 93: 5151-5155.
38. Rittinger, K., Walker, P.A., Eccleston, J.F., Smerdon, S.J. and Gamblin, S.J. (1997) Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature 389: 758-762.
39. Ritzenthaler, C., Nebenführ, A., Movafeghi, A., Stussi-Garauda, C., Behniac, L., Pimplc, P., Staehelinb, L.A. and Robinson, D.G. (2002). Reevaluation of the effects of brefeldin A on plant cells using tobacco bright yellow 2 cells expressing Golgi-targeted green fluorescent protein and COPI antisera. Plant Cell 14: 237-261.
40. Robinson, D.G., Hinz, G. and Holstein, S.E. (1998) The molecular characterization of transport vesicles. Plant Mol. Biol. 38: 49-76.
41. Schimmöller, F., Simon, I. and Pfeffer, S. (1998) Rab GTPases, directors of vesicle docking. J. Biol. Chem. 273: 22161-22164.
42. Scheffzek, K., Ahmadian, M.R., Kabsch, W., Wiesmüller, L., Lautwein, A., Schmitz, F. and Wittinghofer, A. (1997) The ras-GAP complex - structural basis for GTPase activation and its loss in oncogenic ras mutants. Science 277: 333-338.
43. Scheffzek, K., Ahmadian, M.R. and Wittinghofer, A. (1998) GTPase-activating proteins: helping hands to complement an active site. Trends Biochem. Sci. 23: 257-262.
44. Seo, H.S., Choi, C.H., Kim, H.Y., Jeong, J.Y., Lee, S.Y., Cho, M.J. and Bahk, J.D. (1997) Guanine-nucleotide binding and hydrolyzing kinetics of ORrab2, a rice small GTP-binding protein expressed in Escherichia coli. Eur. J. Biochem. 249: 293-300.
45. Sheen, J. (2001) Signal transduction in maize and Arabidosis mesophyll protoplasts. Plant Physiol. 127: 1466-1475.
46. Shirataki, H., Kaibuchi, K., Sakoda, T., Kishida, S., Yamaguchi, T., Wada, K., Miyazaki, M. and Taikai, Y. (1993) Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin. Mol. Cell. Biol. 13: 2061-2068.
47. Simonsen, A., Lippe, R., Christoforidis, S., Gaullier, J.M., Brech, A., Callaghan, J., Toh, B.H., Murphy, C., Zerial, M. and Stenmark, H. (1998) EEA1 links PI (3)K function to Rab5 regulation of endosome fusion. Nature 394: 494-498.
48. Sohn, E.J., Kim, E.S., Zhao, M., Kim, S.J., Kim, H.R., Kim, Y.W., Lee, Y.J., Hillmer, S. Sohn, U.I., Jiang, L. and Hwang, I.H. (2003) Rha1, an Arabidopsis Rab5 homolog, plays a critical role in the vacuolar trafficking of soluble cargo proteins. Plant Cell 15: 1057-1070.
49. Soldati, T., Riederer, M.A. and Pfeffer, S.R. (1993) Rab GDI: a solubilizing and recycling factor for rab9 protein. Mol. Biol. Cell 4: 425-434.
50. Strom, M., Vollmer, P., Tan, T.J. and Gallwitz, D. (1993) A yeast GTPase-activating protein that interacts specifically with a member of the Ypt/Rab family. Nature 361: 736-739.
51. Takeuchi, M., Ueda, T., Yahara, N. and Nakano, A. (2002) Arf1 GTPase plays roles in the protein traffic between the endoplasmic reticulum and the Golgi apparatus in tobacco and Arabidopsis cultured cells. Plant J. 39: 499-515
52. Trahey, M. and McCormick, F. (1987) A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science 238: 542-545.
53. Ueda, T., Yamaguchi, M., Uchimiya, H. and Nakano, A. (2001) Ara6, a plant unique novel type Rab GTPase, functions in the endocytic pathway of Arabidopsis thaliana. EMBO J. 20: 4730-4741.
54. Ullrich, O., Stenmark, H., Alexandrov, K., Huber, L.A., Kaibuchi, K., Sasaki, T., Takai, Y. and Zerial, M. (1993) Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. J. Biol. Chem. 268: 18143-18150.
55. Vollmer, P. and Gallwitz, D. (1995) High expression cloning, purification and assay of Ypt-GTPase-activating proteins. Methods Enzymol. 257: 118-128.
56. Vollmer, P., Will, E., Schegelmann, D., Strom, M. and Gallwitz, D. (1999) Primary structure and biochemical characterization of yeast GTPase activating proteins with substrate preference for the transport GTPase Ypt7p. Eur. J. Biochem. 260: 284-290.
57. Wang, Y., Okamoto, M., Schmitz, F., Hofmann, K. and Südhof, T.C. (1997) Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion. Nature 388: 593-598.
58. Will, E. and Gallwitz, D. (2001) Biochemical characterization of Gyp6p, a Ypt/Rab-specific GTPase-activating protein from yeast J. Biol. Chem. 276: 12135-2139.
59. Xu, G.F., Lin, B., Tanaka, K., Dunn, D., Wood, D., Gesteland, R., White, R., Weiss, R. and Tamanoi, F. (1990) The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements Ira mutants of S. cerevisiae. Cell 63: 835-841.
60. Xiao, G.H., Shoarinejad, F., Jin, F., Golemis, E.A. and Yeung, R.S. (1997) The tuberous sclerosis 2 gene product, tuberin, fonctions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis. J. Biol. Chem. 272: 6097-100.
61. Zheng, H., Mollard, G.F., Kovaleva, V., Stevens, T.H. and Raikhel, N.V. (1999) The plant vesicle-associated SNARE AtVTI1a likely mediates vesicle transport from the trans-Golgi network to the prevacuolar compartment. Mol. Biol. Cell 10: 2251-2264.