The structure of the GTPase-activating domain from p50rhoGAP

Nature

Volumn 385, Issue 6615, 1997, Pages 458-461

  Barrett, Tracey ^a   Xiao, Bing ^a   Dodson, Eleanor J ^b   Dodson, Guy ^a,b   Ludbrook, Steven B ^a   Nurmahomed, Kurshid ^a   Gamblin, Steven J ^a   Musacchio, Andrea ^c   Smerdon, Stephen J ^a   Eccleston, John F ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN;

ALPHA HELIX; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 18144437689     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/385458a0     Document Type: Article

References (22)

1. Paterson, H. F. et al. J. Cell Biol. 111, 1001-1007 (1990).
2. Ridley, A. J. & Hall, A. Cell 70, 389-399 (1992).
3. Ridley, A. J., Paterson, H. F., Johnson, C. L., Diekmann, D. & Hall, A. Cell 70, 401-410 (1992).
4. Ridley, A. J. J. Cell Sci. (suppl.) 18, 127-131 (1994).
5. Bourne, H. R., Sanders, D. A. & McCormick, F. Nature 348, 125-132 (1990).
6. Boguski, M. S. & McCormick, F. Nature 366, 643-654 (1993).
7. Lamarche, N. & Hall, A. Trends Genet. 10, 436-440 (1994).
8. Lancaster, C. A. et al. J. Biol. Chem. 26, 1137-1142 (1994).
9. Hall, A. et al. J. Mol. Biol. 211, 11-16 (1990).
10. Mussachio, A., Cantley, L. C. & Harrison, S. C. Proc. Natl Acad. Sci. USA 93, 14373-14378 (1997).
11. Zheng, Y., Bagrodia, S. & Cerione, R. A. J. Cell Biol. 269, 18727-18730 (1994).
12. Otwinowski, Z. & Minor, W. Data Colleciton and Processing (eds Sawyer, L., Isaacs, N. & Bailey, S.) 556-562 (SERC Daresbury Laboratory, Warringon, 1993).
13. CCP4 Acta Crystallogr. D50, 760-763 (1994).
14. Terwilliger, T. C., Kim, S. H. & Eisenberg, D. Acta Crystallogr. A43, 1-5 (1987).
15. Otwinowski, Z. Isomorphous Replacement and Anomalous Scattering (eds Wolf, W., Evans, P. R. & Leslie, A. G. W.) 80-86 (SERC Daresbury laboratory, Warrington, 1991).
16. Jones, T. A., Zhou, J.-Y., Cowan, S. W. & Kjeldgaard, M. Acta Crystallogr. A47, 110-119 (1991).
17. Lamzin, V. S. & Wilson, K. S. Acta Crystallogr. D49, 127-149 (1993).
18. Carson, M. J. J. Appl. Crystallogr. 24, 958-961 (1991).
19. Settleman, J., Varasingham, V., Foster, L. C. & Weinberg, R. A. Cell 64, 539-549 (1992).
20. Lifschitz, B. et al. Oncogene 2, 113-117 (1988).
21. Cicchetti, P., Mayer, B. J., Thiel, G. & Baltimore, D. Science 257, 803-806 (1992).
22. Otsu, M. et al. Cell 65, 91-104 (1991).