Synthesis and evaluation of 5-aryl-3-(4-hydroxyphenyl)-1,3,4-oxadiazole-2- (3H)-thiones as P-glycoprotein inhibitors

Chemical and Pharmaceutical Bulletin

Volumn 51, Issue 6, 2003, Pages 728-730

  Loetchutinat, Chatchanok ^a   Chau, François ^b   Mankhetkorn, Samlee ^a  

^a BURAPHA UNIVERSITY   (Thailand)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Inhibitor; Multidrug resistance (MDR); Oxadiazolethione; P glycoprotein

Indexed keywords

5 (4 CHLOROPHENYL) 3 (4 HYDROXYPHENYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; 5 (4 NITROPHENYL) 3 (4 HYDROXYPHENYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; 5 PHENYL 3 (4 HYDROXYPHENYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; APIGENIN; GENISTEIN; GLYCOPROTEIN P INHIBITOR; THIOKETONE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG SYNTHESIS; EVALUATION; HUMAN; HUMAN CELL; IC 50; POLYMERIZATION;

EID: 27944463018     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.51.728     Document Type: Article

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