-
1
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge DG, Germain M, Mathai JP, Nguyen M, Shore GC. 2003. Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 22(53):8608-8618.
-
(2003)
Oncogene
, vol.22
, Issue.53
, pp. 8608-8618
-
-
Breckenridge, D.G.1
Germain, M.2
Mathai, J.P.3
Nguyen, M.4
Shore, G.C.5
-
2
-
-
0033591217
-
p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor
-
Budhram-Mahadeo V, Morris PJ, Smith MD, Midgley CA, Boxer LM, Latchman DS. 1999. p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor. J Biol Chem 274:15237-15244.
-
(1999)
J Biol Chem
, vol.274
, pp. 15237-15244
-
-
Budhram-Mahadeo, V.1
Morris, P.J.2
Smith, M.D.3
Midgley, C.A.4
Boxer, L.M.5
Latchman, D.S.6
-
3
-
-
0034671525
-
Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells
-
Butt AJ, Firth SM, King MA, Baxter RC. 2000. Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells. J Biol Chem 275:39174-39181.
-
(2000)
J Biol Chem
, vol.275
, pp. 39174-39181
-
-
Butt, A.J.1
Firth, S.M.2
King, M.A.3
Baxter, R.C.4
-
4
-
-
0034869384
-
Bcl-2 expression in pancreas development and pancreatic cancer progression
-
Campani D, Esposito I, Boggi U, Cecchetti D, Menicagli M, De Negri F, Colizzi L, Del Chiaro M, Mosca F, Fornaciari G, Bevilacqua G. 2001. Bcl-2 expression in pancreas development and pancreatic cancer progression. J Pathol 194(4):444-450.
-
(2001)
J Pathol
, vol.194
, Issue.4
, pp. 444-450
-
-
Campani, D.1
Esposito, I.2
Boggi, U.3
Cecchetti, D.4
Menicagli, M.5
De Negri, F.6
Colizzi, L.7
Del Chiaro, M.8
Mosca, F.9
Fornaciari, G.10
Bevilacqua, G.11
-
5
-
-
0028958705
-
Growth factor modulation of p53-mediated growth arrest versus apoptosis
-
Canman CE, Gilmer TM, Coutts SB, Kastan MB. 1995. Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev 9:606-611.
-
(1995)
Genes Dev
, vol.9
, pp. 606-611
-
-
Canman, C.E.1
Gilmer, T.M.2
Coutts, S.B.3
Kastan, M.B.4
-
6
-
-
0027258466
-
Thymocyte apoptosis induced by p53 dependent and independent pathway
-
Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML, Wyllie AH. 1993. Thymocyte apoptosis induced by p53 dependent and independent pathway. Nature 362:849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
7
-
-
0031595728
-
Analysis of p53, P21WAF1, and TGF-beta1 in human ductal adenocarcinoma of the pancreas: TGF-beta1 protein expression predicts longer survival
-
Coppola D, Lu L, Fruehauf JP, Kyshtoobayeva A, Karl RC, Nicosia SV, Yeatman TJ. 1998. Analysis of p53, P21WAF1, and TGF-beta1 in human ductal adenocarcinoma of the pancreas: TGF-beta1 protein expression predicts longer survival. Am J Clin Pathol 110:16-23.
-
(1998)
Am J Clin Pathol
, vol.110
, pp. 16-23
-
-
Coppola, D.1
Lu, L.2
Fruehauf, J.P.3
Kyshtoobayeva, A.4
Karl, R.C.5
Nicosia, S.V.6
Yeatman, T.J.7
-
8
-
-
0000336139
-
Regression models and life tables
-
Cox DR. 1972. Regression models and life tables. J R Stat Soc 34:187-220.
-
(1972)
J R Stat Soc
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
9
-
-
0035554145
-
Detailed tissue expression of bcl-2, bax, bak, and bcl-x in the normal human pancreas and in chronic pancreatitis, ampullary, and pancreatic ductaladenocarcinomas
-
Evans JD, Cornford PA, Dodson A, Greenhalf W, Foster CS, Neoptolemos JP. 2001. Detailed tissue expression of bcl-2, bax, bak, and bcl-x in the normal human pancreas and in chronic pancreatitis, ampullary, and pancreatic ductaladenocarcinomas. Pancreatology 1(3):254-262.
-
(2001)
Pancreatology
, vol.1
, Issue.3
, pp. 254-262
-
-
Evans, J.D.1
Cornford, P.A.2
Dodson, A.3
Greenhalf, W.4
Foster, C.S.5
Neoptolemos, J.P.6
-
10
-
-
0031715838
-
Bax, but not bcl-2, influences the prognosis of human pancreatic cancer
-
Friess H, Lu Z, Graber HU, Zimmermann A, Adler G, Korc M, Schmid RM, Buchler MW. 1998. bax, but not bcl-2, influences the prognosis of human pancreatic cancer. Gut 43:414-421.
-
(1998)
Gut
, vol.43
, pp. 414-421
-
-
Friess, H.1
Lu, Z.2
Graber, H.U.3
Zimmermann, A.4
Adler, G.5
Korc, M.6
Schmid, R.M.7
Buchler, M.W.8
-
11
-
-
0030665130
-
Genetic progression and heterogeneity in intraductal papillary-mucinous neoplasms of the pancreas
-
Fujii H, Inagaki M, Kasai S, Miyokawa N, Tokusashi Y, Gabrielson E, Hruban RH. 1997. Genetic progression and heterogeneity in intraductal papillary-mucinous neoplasms of the pancreas. Am J Pathol 151:1447-1454.
-
(1997)
Am J Pathol
, vol.151
, pp. 1447-1454
-
-
Fujii, H.1
Inagaki, M.2
Kasai, S.3
Miyokawa, N.4
Tokusashi, Y.5
Gabrielson, E.6
Hruban, R.H.7
-
12
-
-
0027370407
-
Prognostic indicators for survival after resection of pancreatic adenocarcinoma
-
Geer RJ, Brennan MF. 1993. Prognostic indicators for survival after resection of pancreatic adenocarcinoma. Am J Surg 165:68-73.
-
(1993)
Am J Surg
, vol.165
, pp. 68-73
-
-
Geer, R.J.1
Brennan, M.F.2
-
13
-
-
0032957020
-
Bcl-2 expression related to altered p53 protein and its impact on the progression of human pancreatic carcinoma
-
Hu YX, Watanabe H, Ohtsubo K, Yamaguchi Y, Ha A, Motoo Y, Okai T, Sawabu N. 1999. Bcl-2 expression related to altered p53 protein and its impact on the progression of human pancreatic carcinoma. Br J Cancer 80:1075-1079.
-
(1999)
Br J Cancer
, vol.80
, pp. 1075-1079
-
-
Hu, Y.X.1
Watanabe, H.2
Ohtsubo, K.3
Yamaguchi, Y.4
Ha, A.5
Motoo, Y.6
Okai, T.7
Sawabu, N.8
-
14
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan EL, Meier P. 1958. Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481.
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
15
-
-
0034693635
-
K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2, and erbB-3 in resected pancreatic ductal adenocarcinoma
-
Kawesha A, Ghaneh P, Andren-Sandberg A, Ograed D, Skar R, Dawiskiba S, Evans JD, Campbell F, Lemoine N, Neoptolemos JP. 2000. K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2, and erbB-3 in resected pancreatic ductal adenocarcinoma. Int J Cancer 89:469-474.
-
(2000)
Int J Cancer
, vol.89
, pp. 469-474
-
-
Kawesha, A.1
Ghaneh, P.2
Andren-Sandberg, A.3
Ograed, D.4
Skar, R.5
Dawiskiba, S.6
Evans, J.D.7
Campbell, F.8
Lemoine, N.9
Neoptolemos, J.P.10
-
16
-
-
0032525223
-
Histologic and biologic patterns of microscopic pancreatic ductal adenocarcinomas detected incidentally at autopsy
-
Kimura W, Morikane K, Esaki Y, Chan WC, Pour PM. 1998. Histologic and biologic patterns of microscopic pancreatic ductal adenocarcinomas detected incidentally at autopsy. Cancer 82:1839-1849.
-
(1998)
Cancer
, vol.82
, pp. 1839-1849
-
-
Kimura, W.1
Morikane, K.2
Esaki, Y.3
Chan, W.C.4
Pour, P.M.5
-
17
-
-
0031015630
-
Spontaneous overexpression of the long form of Bcl-X protein in a highly resistant P388 leukaemia
-
Kuhl JS, Krajewski S, Duran GE, Reed JC, Sikic BI. 1997. Spontaneous overexpression of the long form of Bcl-X protein in a highly resistant P388 leukaemia. Br J Cancer 75:268-274.
-
(1997)
Br J Cancer
, vol.75
, pp. 268-274
-
-
Kuhl, J.S.1
Krajewski, S.2
Duran, G.E.3
Reed, J.C.4
Sikic, B.I.5
-
18
-
-
0031899556
-
Clinical contribution of bcl-2, p53, and Ki-67 proteins in pancreatic ductal adenocarcinoma
-
Makinen K, Hakala T, Lipponen P, Alhava E, Eskelinen M. 1998. Clinical contribution of bcl-2, p53, and Ki-67 proteins in pancreatic ductal adenocarcinoma. Anticancer Res 18:615-618.
-
(1998)
Anticancer Res
, vol.18
, pp. 615-618
-
-
Makinen, K.1
Hakala, T.2
Lipponen, P.3
Alhava, E.4
Eskelinen, M.5
-
19
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of human box gene
-
Miyashita T, Reed JC. 1995. Tumor suppressor p53 is a direct transcriptional activator of human box gene. Cell 80:293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
20
-
-
0028292480
-
Identification of a p53-dependent negative response element in the bcl-2 gene
-
Miyashita T, Harigai M, Hanada M, Reed JC. 1994. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res 54:3130-3135.
-
(1994)
Cancer Res
, vol.54
, pp. 3130-3135
-
-
Miyashita, T.1
Harigai, M.2
Hanada, M.3
Reed, J.C.4
-
21
-
-
0035087309
-
Apoptosis and expression of Bcl-2 and Bax proteins in invasive ductal carcinoma of the pancreas
-
Nio Y, Iguchi C, Yamasawa K, Sasaki S, Takamura M, Toga T, Dong M, Itakura M, Tamura K. 2001. Apoptosis and expression of Bcl-2 and Bax proteins in invasive ductal carcinoma of the pancreas. Pancreas 22(3):230-239.
-
(2001)
Pancreas
, vol.22
, Issue.3
, pp. 230-239
-
-
Nio, Y.1
Iguchi, C.2
Yamasawa, K.3
Sasaki, S.4
Takamura, M.5
Toga, T.6
Dong, M.7
Itakura, M.8
Tamura, K.9
-
22
-
-
0028888708
-
Long-term survival after resection for ductal adenocarcinoma of the pancreas: Is in really improving?
-
Nitecki SS, Sarr MG, Colby TV, et al. 1995. Long-term survival after resection for ductal adenocarcinoma of the pancreas: Is in really improving? Ann Surg 221: 59-66.
-
(1995)
Ann Surg
, vol.221
, pp. 59-66
-
-
Nitecki, S.S.1
Sarr, M.G.2
Colby, T.V.3
-
23
-
-
0030805125
-
Overexpression of Bcl-X protein in primary breast cancer is associated with high tumor grade and nodal metastases
-
Olopade OI, Adeyanju MO, Safa AR, Hagos F, Mick R, Thompson CB, Recant WM. 1997. Overexpression of Bcl-X protein in primary breast cancer is associated with high tumor grade and nodal metastases. Cancer J Sci Am 3:230-237.
-
(1997)
Cancer J Sci Am
, vol.3
, pp. 230-237
-
-
Olopade, O.I.1
Adeyanju, M.O.2
Safa, A.R.3
Hagos, F.4
Mick, R.5
Thompson, C.B.6
Recant, W.M.7
-
24
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerated programmed cell death
-
Oltvai ZN, Milliman CL, Korsmeyer SJ. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerated programmed cell death. Cell 74:609-611.
-
(1993)
Cell
, vol.74
, pp. 609-611
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
25
-
-
8944263468
-
Association between cisplatin resistance and mutation of p53 gene and reduced Bax expression in ovarian carcinoma cell system
-
Perego P, Giarola M, Righetti SC, Supino R, Caserini C, Delia D, Pierotti MA, Miyashita T, Reed JC, Zunino F. 1996. Association between cisplatin resistance and mutation of p53 gene and reduced Bax expression in ovarian carcinoma cell system. Cancer Res 56:556-562.
-
(1996)
Cancer Res
, vol.56
, pp. 556-562
-
-
Perego, P.1
Giarola, M.2
Righetti, S.C.3
Supino, R.4
Caserini, C.5
Delia, D.6
Pierotti, M.A.7
Miyashita, T.8
Reed, J.C.9
Zunino, F.10
-
26
-
-
0017365573
-
Design and analysis of randomised clinical trials requiring prolonged observation of each patient
-
Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG. 1997. Design and analysis of randomised clinical trials requiring prolonged observation of each patient. Br J Cancer 35:1-39.
-
(1997)
Br J Cancer
, vol.35
, pp. 1-39
-
-
Peto, R.1
Pike, M.C.2
Armitage, P.3
Breslow, N.E.4
Cox, D.R.5
Howard, S.V.6
Mantel, N.7
McPherson, K.8
Peto, J.9
Smith, P.G.10
-
27
-
-
0027464267
-
Cell cycle analysis of p53-induced cell death in murine etythroleukemia cells
-
Ryan JJ, Danish R, Gottlieb CA, Clarke MF. 1993. Cell cycle analysis of p53-induced cell death in murine etythroleukemia cells. Mol Cell Biol 13:711-719.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 711-719
-
-
Ryan, J.J.1
Danish, R.2
Gottlieb, C.A.3
Clarke, M.F.4
-
28
-
-
0037128687
-
Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma
-
Sarela AI, Verbeke CS, Ramsdale J, Davies CL, Markham AF, Guillou PJ. 2002. Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. Br J Cancer 86(6):886-892.
-
(2002)
Br J Cancer
, vol.86
, Issue.6
, pp. 886-892
-
-
Sarela, A.I.1
Verbeke, C.S.2
Ramsdale, J.3
Davies, C.L.4
Markham, A.F.5
Guillou, P.J.6
-
29
-
-
0032460609
-
Ki-ras and p53 gene mutations in pancreatic ductal carcinoma: A relationship with tumour phenotype and survival
-
Sessa F, Bonato M, Bisoni D, Ranzani GN, Capella C. 1998. Ki-ras and p53 gene mutations in pancreatic ductal carcinoma: A relationship with tumour phenotype and survival. Eur J Histochem 42:67-76.
-
(1998)
Eur J Histochem
, vol.42
, pp. 67-76
-
-
Sessa, F.1
Bonato, M.2
Bisoni, D.3
Ranzani, G.N.4
Capella, C.5
-
30
-
-
0029849620
-
Cancer cell cycles
-
Sherr CJ. 1996. Cancer cell cycles. Science 274:1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
31
-
-
0030443653
-
Bcl-2 and p53 expression in resectable pancreatic carcinoma: Association with clinical outcome
-
Sinicrope FA, Evans DB, Leach SD, Cleary KR, Fenoglio CJ, Lee JJ, Abbruzzese JL. 1996. Bcl-2 and p53 expression in resectable pancreatic carcinoma: Association with clinical outcome. Clin Cancer Res 2:2015-2022.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 2015-2022
-
-
Sinicrope, F.A.1
Evans, D.B.2
Leach, S.D.3
Cleary, K.R.4
Fenoglio, C.J.5
Lee, J.J.6
Abbruzzese, J.L.7
-
33
-
-
0034329115
-
Resected adenocarcinoma of the pancreas-616 patients: Results, outcomes, and prognostic indicators
-
Sohn TA, Yeo CJ, Cameron JL, Koniaris L, Kaushal S, Abrams RA, Sauter PK, Coleman J, Hruban RH, Lillemoe KD. 2000. Resected adenocarcinoma of the pancreas-616 patients: Results, outcomes, and prognostic indicators. J Gastrointest Surg 4:567-579.
-
(2000)
J Gastrointest Surg
, vol.4
, pp. 567-579
-
-
Sohn, T.A.1
Yeo, C.J.2
Cameron, J.L.3
Koniaris, L.4
Kaushal, S.5
Abrams, R.A.6
Sauter, P.K.7
Coleman, J.8
Hruban, R.H.9
Lillemoe, K.D.10
-
34
-
-
85047655469
-
Pancreatic cancer incidence in U.S. blacks and whites. 1973-1999
-
Stat Bite: 2002. Pancreatic cancer incidence in U.S. blacks and whites. 1973-1999. J Natl Cancer Inst 94(22):1671.
-
(2002)
J Natl Cancer Inst
, vol.94
, Issue.22
, pp. 1671
-
-
Bite, S.1
-
35
-
-
0344348993
-
Analysis of the p53/BAX pathway in colorectal cancer: Low BAX is a negative prognostic factor in patients with resected liver metastases
-
Sturm I, Kohne CH, Wolff G, Petrowsky H, Hillebrand T, Hauptmann S, Lorenz M, Dorken B, Daniel PT. 1999. Analysis of the p53/BAX pathway in colorectal cancer: Low BAX is a negative prognostic factor in patients with resected liver metastases. J Clin Oncol 17(5):1364-1374.
-
(1999)
J Clin Oncol
, vol.17
, Issue.5
, pp. 1364-1374
-
-
Sturm, I.1
Kohne, C.H.2
Wolff, G.3
Petrowsky, H.4
Hillebrand, T.5
Hauptmann, S.6
Lorenz, M.7
Dorken, B.8
Daniel, P.T.9
-
36
-
-
0036311122
-
p53-independent apoptosis is induced by the p19ARF tumor suppressor
-
Tsuji K, Mizumoto K, Sudo H, Kouyama K, Ogata E, Matsuoka M. 2002. p53-independent apoptosis is induced by the p19ARF tumor suppressor. Biochem Biophys Res Commun 295(3):621-629.
-
(2002)
Biochem Biophys Res Commun
, vol.295
, Issue.3
, pp. 621-629
-
-
Tsuji, K.1
Mizumoto, K.2
Sudo, H.3
Kouyama, K.4
Ogata, E.5
Matsuoka, M.6
-
38
-
-
0028670932
-
p53 expression in human pancreatic cancer correlates with enhanced biological aggressiveness
-
Yokoyama M, Yamanaka Y, Friess H, Buchler M, Korc M. 1994. p53 expression in human pancreatic cancer correlates with enhanced biological aggressiveness. Anticancer Res 14:2477-2484.
-
(1994)
Anticancer Res
, vol.14
, pp. 2477-2484
-
-
Yokoyama, M.1
Yamanaka, Y.2
Friess, H.3
Buchler, M.4
Korc, M.5
-
39
-
-
0029801085
-
The apoptosis associated gammaray response of Bcl-X(L) depends on normal p53 function
-
Zhan Q, Alamo I, Yu K, Boise LH, Cherney B, Tosato G, O'Connor PM, Fornace AJ, Jr. 1996. The apoptosis associated gammaray response of Bcl-X(L) depends on normal p53 function. Oncogene 13:2287-2293.
-
(1996)
Oncogene
, vol.13
, pp. 2287-2293
-
-
Zhan, Q.1
Alamo, I.2
Yu, K.3
Boise, L.H.4
Cherney, B.5
Tosato, G.6
O'Connor, P.M.7
Fornace Jr., A.J.8
|