-
1
-
-
0037150730
-
Polycomb repression: From cellular memory to cellular proliferation and cancer
-
Jacobs JJ, van Lohuizen M. Polycomb repression: from cellular memory to cellular proliferation and cancer. Biochim Biophys Acta 2002, 1602: 151-161.
-
(2002)
Biochim Biophys Acta
, vol.1602
, pp. 151-161
-
-
Jacobs, J.J.1
van Lohuizen, M.2
-
2
-
-
0033552813
-
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
-
Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 1999, 397: 164-168.
-
(1999)
Nature
, vol.397
, pp. 164-168
-
-
Jacobs, J.J.1
Kieboom, K.2
Marino, S.3
DePinho, R.A.4
van Lohuizen, M.5
-
3
-
-
0035866814
-
BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas
-
Bea S, Tort F, Pinyol M et al. BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas. Cancer Res 2001, 61: 2409-2412.
-
(2001)
Cancer Res
, vol.61
, pp. 2409-2412
-
-
Bea, S.1
Tort, F.2
Pinyol, M.3
-
4
-
-
0035906853
-
The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression
-
Vonlanthen S, Heighway J, Altermatt HJ et al. The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression. Br J Cancer 2001, 84: 1372-1376.
-
(2001)
Br J Cancer
, vol.84
, pp. 1372-1376
-
-
Vonlanthen, S.1
Heighway, J.2
Altermatt, H.J.3
-
5
-
-
0035877978
-
Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma
-
van Kemenade FJ, Raaphorst FM, Blokzijl T et al. Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma. Blood 2001, 97: 3996-3901.
-
(2001)
Blood
, vol.97
, pp. 3896-3901
-
-
van Kemenade, F.J.1
Raaphorst, F.M.2
Blokzijl, T.3
-
6
-
-
0037214382
-
Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1
-
Itahana K, Zou Y, Itahana Y et al. Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1. Mol Cell Biol 2003, 23: 389-401.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 389-401
-
-
Itahana, K.1
Zou, Y.2
Itahana, Y.3
-
7
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003, 423: 255-260.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
8
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
Park IK, Qian D, Kiel M et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003, 423: 302-305.
-
(2003)
Nature
, vol.423
, pp. 302-305
-
-
Park, I.K.1
Qian, D.2
Kiel, M.3
-
9
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky AV, Pardal R. Iwashita T, Park IK, Clarke MF, Morrison SJ. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003, 425: 962-967.
-
(2003)
Nature
, vol.425
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.K.4
Clarke, M.F.5
Morrison, S.J.6
-
10
-
-
9044220225
-
3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region
-
Sithanandam G, Latif F, Duh FM et al. 3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region. Mol Cell Biol 1996, 16: 868-876.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 868-876
-
-
Sithanandam, G.1
Latif, F.2
Duh, F.M.3
-
11
-
-
14044263532
-
MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1
-
Voncken JW, Niessen H, Neufeld B et al. MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1. J Biol Chem 2005, 280: 5178-5187.
-
(2005)
J Biol Chem
, vol.280
, pp. 5178-5187
-
-
Voncken, J.W.1
Niessen, H.2
Neufeld, B.3
-
12
-
-
0029912650
-
3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways
-
Ludwig S. Engel K. Hoffmeyer A et al. 3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways. Mol Cell Biol 1996, 16: 6687-6697.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6687-6697
-
-
Ludwig, S.1
Engel, K.2
Hoffmeyer, A.3
-
13
-
-
0036403184
-
Rationale for Ras and raf-kinase as a target for cancer therapeutics
-
Nottage M, Siu LL. Rationale for Ras and raf-kinase as a target for cancer therapeutics. Curr Pharm Des 2002, 8: 2231-2242.
-
(2002)
Curr Pharm Des
, vol.8
, pp. 2231-2242
-
-
Nottage, M.1
Siu, L.L.2
-
14
-
-
0036072924
-
Ras/Raf signalling and emerging pharmacotherapeutic targets
-
Kolch W. Ras/Raf signalling and emerging pharmacotherapeutic targets. Expert Opin Pharmacother 2002, 3: 709-718.
-
(2002)
Expert Opin Pharmacother
, vol.3
, pp. 709-718
-
-
Kolch, W.1
-
15
-
-
0038697566
-
Raf proteins and cancer: B-Raf is identified as a mutational target
-
Mercer KE, Pritchard CA. Raf proteins and cancer: B-Raf is identified as a mutational target. Biochim Biophys Acta 2003, 1653: 25-40.
-
(2003)
Biochim Biophys Acta
, vol.1653
, pp. 25-40
-
-
Mercer, K.E.1
Pritchard, C.A.2
-
16
-
-
0032522816
-
High-intensity Raf signals convert mitotic cell cycling into cellular growth
-
Kerkhoff E, Rapp UR. High-intensity Raf signals convert mitotic cell cycling into cellular growth. Cancer Res 1998, 58: 1636-1640.
-
(1998)
Cancer Res
, vol.58
, pp. 1636-1640
-
-
Kerkhoff, E.1
Rapp, U.R.2
-
17
-
-
2942607408
-
Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis
-
Houben R, Becker JC, Kappel A et al. Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis. J Carcinog 2004, 3: 6.
-
(2004)
J Carcinog
, vol.3
, pp. 6
-
-
Houben, R.1
Becker, J.C.2
Kappel, A.3
-
18
-
-
0035392955
-
Promoter hypermethylation: A common cause of reduced p16(INK4a) expression in uveal melanoma
-
van der Velden PA, Metzelaar-Blok JA, Bergman W et al. Promoter hypermethylation: a common cause of reduced p16(INK4a) expression in uveal melanoma. Cancer Res 2001, 61: 5303-5306.
-
(2001)
Cancer Res
, vol.61
, pp. 5303-5306
-
-
van der Velden, P.A.1
Metzelaar-Blok, J.A.2
Bergman, W.3
-
19
-
-
0036635757
-
Human cell lines engineered for tetracycline-regulated expression of tumor suppressor candidate genes from a frequently affected chromosomal region, 3p21
-
Protopopov AI, Li J, Winberg G et al. Human cell lines engineered for tetracycline-regulated expression of tumor suppressor candidate genes from a frequently affected chromosomal region, 3p21. J Gene Med 2002, 4: 397-406.
-
(2002)
J Gene Med
, vol.4
, pp. 397-406
-
-
Protopopov, A.I.1
Li, J.2
Winberg, G.3
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