Purification and characterization of a furfural reductase (FFR) from Escherichia coli strain LYO1 - An enzyme important in the detoxification of furfural during ethanol production

Journal of Biotechnology

Volumn 121, Issue 2, 2006, Pages 154-164

  Gutiérrez, Tony ^a   Ingram, Lonnie O ^a   Preston, James F ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Escherichia coli; Furfural reductase (FFR); Furfural reduction; Furfuryl alcohol

Indexed keywords

DETOXIFICATION; ESCHERICHIA COLI; ETHANOL; GELS; HIGH TEMPERATURE EFFECTS; MOLECULAR WEIGHT; PURIFICATION;

BACTERIA STRAIN; FURFURYL ALCOHOL; FURFURYL REDUCTASE (FFR); FURFURYL REDUCTION;

ENZYMES;

2 ACETYLFURAN; ACETALDEHYDE; ALCOHOL; ALDEHYDE; BENZALDEHYDE; DIMER; FURAN DERIVATIVE; FURFURAL; FURFURAL REDUCTASE; GLUCOSE; HOLOENZYME; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; XYLOSE;

ALCOHOL PRODUCTION; ARTICLE; CATALYSIS; DETOXIFICATION; ENZYME ANALYSIS; ENZYME PURIFICATION; ESCHERICHIA COLI; GEL ELECTROPHORESIS; GEL FILTRATION; MOLECULAR WEIGHT; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY;

ALDEHYDE REDUCTASE; BACTERIAL PROTEINS; ESCHERICHIA COLI; ETHANOL; FURALDEHYDE; OXIDOREDUCTASES; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 29944442549     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2005.07.003     Document Type: Article

References (37)

1. A.F. Azhar, M.K. Bery, A.R. Colcord, R.S. Roberts, and G.V. Corbitt Factors affecting alcohol fermentation of wood acid hydrolyzate Biotechnol. Bioeng. Symp. 11 1981 293 300
2. N. Banerjee, R. Bhatnagar, and L. Viswanathan Inhibition of glycolysis by furfural in Saccharomyces cerevisiae Appl. Microbiol. Biotechnol. 11 1981 226 228
3. K. Bauer, D. Garbe, and H. Surburg Common Fragrance and Flavor Materials 1990 VCH Publishers Inc. New York
4. D.S. Beall, K. Ohta, and L.O. Ingram Parametric studies of ethanol production from xylose and other sugars by recombinant Escherichia coli Biotechnol. Bioeng. 38 1991 296 303
5. R. Boopathy, H. Bokang, and L. Daniels Biotransformation of furfural and 5-hydroxymethyl furfural by enteric bacteria J. Ind. Microbiol. 11 1993 147 150
6. R. Boopathy, and L. Daniels Isolation and characterization of a furfural degrading sulfate-reducing bacterium from an anaerobic digester Curr. Microbiol. 23 1991 327 332
7. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
8. G. Brune, S.M. Schoberth, and H. Sahm Growth of a strictly anaerobic bacterium on furfural (2-furaldehyde) Appl. Environ. Microbiol. 46 1983 1187 1192
9. F.M. Dean Naturally Occurring Ring Compounds 1963 Butterworths London
10. M.E. Diaz de Villegas, P. Villa, M. Guerra, E. Rodriguez, D. Redondo, and A. Martinez Conversion of furfural into furfuryl alcohol by Saccharomyces cerevisiae 354 Acta Biotechnol. 12 1992 351 354
11. A.P. Dunlop Furfural formation and behaviour Ind. Eng. Chem. 40 1948 204 209
12. M. Folkerts, U. Ney, H. Kneifel, E. Stackebrandt, E.G. Witte, H. Forstel, S.M. Schoberth, and H. Sahm Desulfovibrio furfuralis sp. nov., a furfural degrading strictly anaerobic bacterium Syst. Appl. Microbiol. 11 1989 161 169
13. R.N. Goldberg, Y.B. Tewari, D. Bell, K. Fazio, and E. Anderson Thermodynamics of enzyme-catalyzed reactions. Part 1. Oxidoreductases J. Phys. Chem. 22 1993 515 579
14. T.J. Gross, A. Perez-Matos, and R.A. Bender Roles of the glutamate synthetase, gltBD, and gltF in nitrogen metabolism of Escherichia coli and Klebsiella aerogenes J. Bacteriol. 183 2001 6607 6619
15. S. Grupta, F. Mat-Jan, M. Latifi, and D.P. Clark Acetaldehyde dehydrogenase activity of the AdhE protein of Escherichia coli is inhibited by intermediates in ubiquinone synthesis FEMS Microbiol. Lett. 182 2000 51 55
16. T. Gutierrez, M.L. Buszko, L.O. Ingram, and J.F. Preston Reduction of furfural to furfuryl alcohol by ethanologenic strains of bacteria and its effect on ethanol production from xylose Appl. Biochem. Biotechnol. 98-100 2002 327 340
17. S.W. Hong, H.E. Han, and K.S. Chae Detection of furfural and 2-furoic acid in bacterial cultures by high pressure liquid chromatography J. Liq. Chromatogr. 4 1981 285 292
18. J.B. Jones, and D.R. Dodds Enzymes in organic synthesis 17. Oxidoreductions of alcohols, aldehydes, and ketones using chemically modified horse liver alcohol dehydrogenases Can. J. Chem. 57 1979 2533 2538
19. K. Koenig, and J.R. Andreesen Xanthine dehydrogenase and 2-furoyl-coenzyme A dehydrogenase from Pseudomonas putida Fu1: two molybdenum-containing dehydrogenases of novel structural composition J. Bacteriol. 172 1990 5999 6009
20. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
21. B.U. Lee, B.S. Yu, K.J. Lee, and Y.C. Hah Purification and characterization of the regulatory substance of furfural biodegradation in Pseudomonas fluorescens Korean J. Microbiol. 23 1985 241 247
22. A. Martinez, M.E. Rodriguez, M.L. Wells, S.W. York, J.F. Preston, and L.O. Ingram Detoxification of dilute acid hydrolysates of lignocellulose with lime Biotechnol. Prog. 17 2001 287 293
23. T. Modig, G. Lidén, and M.J. Taherzadeh Inhibition effects of furfural on alcohol dehydrogenase, aldehyde dehydrogenase and pyruvate dehydrogenase Biochem. J. 363 2002 769 776
24. L. Ornstein Disc electrophoresis. I. Background and theory Ann. N.Y. Acad. Sci. 121 1964 321
25. E. Palmqvist, J.S. Almeida, and B. Hahn-Hagerdal Influence of furfural on anaerobic glycolytic kinetics of Saccharomyces cerevisiae in batch culture Biotechnol. Bioeng. 62 1999 447 454
26. T.D. Ranatunga, J. Jervis, R.F. Helm, J.D. McMillan, and C. Hatzis Identification of inhibitory components toxic toward Zymomonas mobilis CP4(pZB5) xylose fermentation Appl. Biochem. Biotechnol. 67 1997 185 195
27. M. Russel, and P. Model Sequence of thioredoxin reductase from Escherichia coli. Relationship to other flavoprotein disulfide reductases J. Biol. Chem. 263 1988 9015 9019
28. B. Sanchez, and J. Bautista Effects of furfural and 5- hydroxymethylfurfural on the fermentation of Saccharomyces cerevisiae and biomass production from Candida guilliermondii Enzyme Microbiol. Technol. 10 1988 315 318
29. 1H NMR J. Microbiol. Methods 17 1993 85 90
30. M.J. Taherzadeh, L. Gustafsson, C. Niklasson, and G. Liden Conversion of furfural in aerobic and anaerobic batch fermentation of glucose by Saccharomyces cerevisiae J. Biosci. Bioeng. 87 1999 169 174
31. M.J. Taherzadeh, C. Niklasson, and G. Liden Conversion of dilute-acid hydrolyzates of spruce and birch to ethanol by fed-batch fermentation Biores. Technol. 69 1999 59 66
32. A.M. Vitrinskaya, and G.A. Soboleva Influence of furfural on the energy metabolism of fodder yeast Appl. Biochem. Microbiol. 11 1975 579 585
33. C.F. Wahlbom, and B. Hahn-Hagerdal Furfural, 5-hydroxyfurfural, and acetoin act as external electron acceptors during anaerobic fermentation of xylose in recombinant Saccharomyces cerevisiae Biotechnol. Bioeng. 78 2002 172 178
34. P. Wang, J.E. Brenchley, and A.E. Humphrey Screening microorganisms for utilization of furfural and possible intermediates in its degradative pathway Biotechnol. Lett. 16 1994 977 982
35. B. Weigert, K. Klein, M. Rizzi, C. Lauterbach, and H. Dellweg Influence of furfural on the aerobic growth of the yeast Pichia stipitis Biotechnol. Lett. 10 1988 895 900
36. L.P. Yomano, S.W. York, and L.O. Ingram Isolation and characterization of ethanol tolerant mutants of Escherichia coli KO11 for fuel ethanol production J. Ind. Microbiol. Biotechnol. 20 1998 132 138
37. J. Zaldivar, A. Martinez, and L.O. Ingram Effect of selected aldehydes on the growth and fermentation of ethanologenic Escherichia coli Biotechnol. Bioeng. 65 1999 24 33