Study of the interaction of antiplasmodial strychnine derivatives with the glycine receptor

European Journal of Pharmacology

Volumn 530, Issue 1-2, 2006, Pages 15-22

  Philippe, Geneviève ^a   Nguyen, Laurent ^a,d   Angenot, Luc ^a   Frédérich, Michel ^a   Moonen, Gustave ^a,b   Tits, Monique ^a   Rigo, Jean Michel ^a,c  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c HASSELT UNIVERSITY   (Belgium)

^d NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

3H strychnine binding; Antimalarial drug; Glycine receptor; Patch clamp; Strychnine

Indexed keywords

ALKALOID; ANTIMALARIAL AGENT; GLYCINE RECEPTOR; PROTOSTRYCHNINE; STRYCHNINE; STRYCHNINE DERIVATIVE; STRYCHNOGUCINE B; STRYCHNOHEXAMINE; SUNGUCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; EMBRYO; NERVE CELL CULTURE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SPINAL CORD; STRYCHNOS;

ALKALOIDS; ANIMALS; ANTIMALARIALS; BINDING, COMPETITIVE; CARBAZOLES; CELLS, CULTURED; DIMERIZATION; GABA ANTAGONISTS; MEDICINE, AFRICAN TRADITIONAL; MEMBRANE POTENTIALS; MOLECULAR STRUCTURE; NEURONS; PATCH-CLAMP TECHNIQUES; PLANT ROOTS; PYRIDAZINES; RADIOLIGAND ASSAY; RATS; RECEPTORS, GLYCINE; SPINAL CORD; STRUCTURE-ACTIVITY RELATIONSHIP; STRYCHNINE; STRYCHNOS; TRITIUM;

EID: 29844447548     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.11.048     Document Type: Article

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