Requirement of the Fc receptor common γ-chain for γδ T cell-mediated promotion of murine experimental autoimmune encephalomyelitis

European Journal of Immunology

Volumn 35, Issue 12, 2005, Pages 3487-3492

  Szalai, Alexander J ^a   Hu, Xianzhen ^b   Raman, Chander ^a   Barnum, Scott R ^b,c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c The University of Alabama at Birmingham   (United States)

Author keywords

T cells; EAE; Fc receptor

Indexed keywords

CD3 ANTIGEN; FC RECEPTOR;

ADOPTIVE TRANSFER; ALLERGIC ENCEPHALOMYELITIS; ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; EFFECTOR CELL; GENE DELETION; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC CODE; GENETIC SUSCEPTIBILITY; HUMORAL IMMUNITY; IMMUNOREGULATION; INNATE IMMUNITY; LIGAND BINDING; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SPLEEN CELL; T LYMPHOCYTE; WILD TYPE;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD3; CHRONIC DISEASE; DISEASE PROGRESSION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENETIC PREDISPOSITION TO DISEASE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, FC; T-LYMPHOCYTE SUBSETS;

EID: 29744432137     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200535285     Document Type: Article

References (29)

1. Sospedra, M. and Martin, R., Immunology of multiple sclerosis. Annu. Rev. Immunol. 2005. 23: 683-747.
2. Takai, T., Roles of Fc receptors in autoimmunity. Nat. Rev. Immunol. 2002. 2: 580-592.
3. Abdul-Majid, K. B., Stefferl, A., Bourquin, C., Lassmann, H., Linington, C., Olsson, T., Kleinau, S. and Harris, R. A., Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis. Scand. J. Immunol. 2002. 55: 70-81.
4. Lock, C., Hermans, G., Pedotti, R., Brendolan, A., Schadt, E., Garren, H., Langer-Gould, A. et al., Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat. Med. 2002. 8: 500-508.
5. Robbie-Ryan, M., Tanzola, M. B., Secor, V. H. and Brown, M. A., Cutting edge: both activating and inhibitory Fc receptors expressed on mast cells regulate experimental allergic encephalomyelitis disease severity. J. Immunol. 2003. 170: 1630-1634.
6. Pedotti, R., DeVoss, J. J., Youssef, S., Mitchell, D., Wedemeyer, J., Madanat, R., Garren, H. et al., Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proc. Natl. Acad. Sci. USA 2003. 100: 1867-1872.
7. Barnes, N., Gavin, A. L., Tan, P. S., Mottram, P., Koentgen, F. and Hogarth, P. M., FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 2002. 16: 379-389.
8. Rajan, A. J., Gao, Y. L., Raine, C. S. and Brosnan, C. F., A pathogenic role for gamma delta T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse. J. Immunol. 1996. 157: 941-949.
9. Spahn, T. W., Issazadah, S., Salvin, A. J. and Weiner, H. L., Decreased severity of myelin oligodendrocyte glycoprotein peptide 33-35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene. Eur. J. Immunol. 1999. 29: 4060-4071.
10. Ponomarev, E. D. and Dittel, B. N., Gamma delta T cells regulate the extent and duration of inflammation in the central nervous system by a Fas ligand-dependent mechanism. J. Immunol. 2005. 174: 4678-4687.
11. Ponomarev, E. D., Novikova, M., Yassai, M., Szczepanik, M., Gorski, J. and Dittel, B. N., Gamma delta T cell regulation of IFN-gamma production by central nervous system-infiltrating encephalitogenic T cells: correlation with recovery from experimental autoimmune encephalomyelitis. J. Immunol. 2004. 173: 1587-1595.
12. Odyniec, A., Szczepanik, M., Mycko, M. P., Stasiolek, M., Raine, C. S. and Selmaj, K. W., Gammadelta T cells enhance the expression of experimental autoimmune encephalomyelitis by promoting antigen presentation and IL-12 production. J. Immunol. 2004. 173: 682-694.
13. Ohno, H., Ono, S., Hirayama, N., Shimada, S. and Saito, T., Preferential usage of the Fc receptor gamma chain in the T cell antigen receptor complex by gamma/delta T cells localized in epithelia. J. Exp. Med. 1994. 179: 365-369.
14. Hayes, S. M. and Love, P. E., Distinct structure and signaling potential of the gamma delta TCR complex. Immunity 2002. 16: 827-838.
15. Qian, D., Sperling, A. I., Lancki, D. W., Tatsumi, Y., Barrett, T. A., Bluestone, J. A. and Fitch, F. W., The gamma chain of the high-affinity receptor for IgE is a major functional subunit of the T-cell antigen receptor complex in gamma delta T lymphocytes. Proc. Natl. Acad. Sci. USA 1993. 90: 11875-11879.
16. Park, S. Y., Arase, H., Wakizaka, K., Hirayama, N., Masaki, S., Sato, S., Ravetch, J. V. and Saito, T., Differential contribution of the FcR gamma chain to the surface expression of the T cell receptor among T cells localized in epithelia: analysis of FcR gamma-deficient mice. Eur. J. Immunol. 1995. 25: 2107-2110.
17. Davis, R. S., Dennis, G. Jr., Odom, M. R., Gibson, A. W., Kimberly, R. P., Burrows, P. D. and Cooper, M. D., Fc receptor homologs: newest members of a remarkably diverse Fc receptor gene family. Immunol. Rev. 2002. 190: 123-136.
18. Nimmerjahn, F., Bruhns, P., Horiuchi, K. and Ravetch, J. V., FcgammaRIV: a novel FcR with distinct IgG subclass specificity. Immunity 2005. 23: 41-51.
19. Hayes, S. M., Shores, E. W. and Love, P. E., An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors. Immunol. Rev. 2003. 191: 28-37.
20. Rajan, A. J., Mein, J. D. and Brosnan, C. F., The effect of gammadelta T cell depletion on cytokine gene expression in experimental allergic encephalomyelitis. J. Immunol. 1998. 160: 5955-5962.
21. Rajan, A. J., Asensio, V. C., Campbell, I. L. and Brosnan, C. F., Experimental autoimmune encephalomyelitis on the SJL mouse: effect of gamma delta T cell depletion on chemokine and chemokine receptor expression in the central nervous system. J. Immunol. 2000. 164: 2120-2130.
22. Secor, V. H., Secor, W. E., Gutekunst, C. A. and Brown, M. A., Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis. J. Exp. Med. 2000. 191: 813-822.
23. Brown, M. A., Tanzola, M. B. and Robbie-Ryan, M., Mechanisms underlying mast cell influence on EAE disease course. Mol. Immunol. 2002. 38: 1373-1378.
24. Nambiar, M. P., Fisher, C. U., Kumar, A., Tsokos, C. G., Warke, V. G. and Tsokos, G. C., Forced expression of the Fc receptor gamma-chain renders human T cells hyperresponsive to TCR/CD3 stimulation. J. Immunol. 2003. 170: 2871-2876.
25. Hazenbos, W. L., Gessner, J. E., Hofhuis, F. M., Kuipers, H., Meyer, D., Heijnen, I. A., Schmidt, R. E. et al., Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity 1996. 5: 181-188.
26. Takai, T., Ono, M., Hikida, M., Ohmori, H. and Ravetch, J. V., Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature 1996. 379: 346-349.
27. Fossati-Jimack, L., Ioan-Facsinay, A., Reininger, L., Chicheportiche, Y., Watanabe, N., Saito, T., Hofhuis, F. M. et al., Markedly different pathogenicity of four immunoglobulin G isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III. J. Exp. Med. 2000. 191: 1293-1302.
28. Szalai, A. J., Nataf, S., Hu, X. Z. and Barnum, S. R., Experimental allergic encephalomyelitis is inhibited in transgenic mice expressing human C-reactive protein. J. Immunol. 2002. 168: 5792-5797.
29. Lyons, J. A., Ramsbottom, M. J., Trotter, J. L. and Cross, A. H., Identification of the encephalitogenic epitopes of CNS proteolipid protein in BALB/c mice. J. Autoimmun. 2002. 19: 195-201.