Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 3, 2006, Pages 592-595

  Tao, Yun Hai ^a   Yuan, Zheng ^a   Tang, Xiao Qiao ^a   Xu, Hui Bi ^a   Yang, Xiang Liang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

4 Hydroxybenzaldehyde; 4 Hydroxybenzylamine; GABA transaminase; Inhibition; Succinic semialdehyde dehydrogenase

Indexed keywords

2 OXOGLUTARIC ACID; 4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID; 4 HYDROXYBENZALDEHYDE; BENZENE; CARBONYL DERIVATIVE; HYDROXYL GROUP; SUCCINATE SEMIALDEHYDE DEHYDROGENASE;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME SUBSTRATE; STRUCTURE ACTIVITY RELATION;

4-AMINOBUTYRATE TRANSAMINASE; BENZALDEHYDES; BINDING SITES; ENZYME INHIBITORS; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE;

EID: 29544451138     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.10.040     Document Type: Article

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