메뉴 건너뛰기




Volumn 96, Issue 12 SUPPL. 2, 2005, Pages 29-31

Phosphodiesterase 5 mechanisms and therapeutic applications

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; NITRIC OXIDE; PHOSPHODIESTERASE V; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; TADALAFIL; VARDENAFIL;

EID: 29544437486     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2005.07.008     Document Type: Article
Times cited : (48)

References (14)
  • 1
    • 0034660235 scopus 로고    scopus 로고
    • Erectile dysfunction
    • T.F. Lue Erectile dysfunction N Engl J Med 342 2000 1802 1813
    • (2000) N Engl J Med , vol.342 , pp. 1802-1813
    • Lue, T.F.1
  • 2
    • 3342887762 scopus 로고    scopus 로고
    • Novel nitric oxide signaling mechanisms regulate the erectile response
    • A.L. Burnett Novel nitric oxide signaling mechanisms regulate the erectile response Int J Impot Res 16 suppl 1 2004 S15 S19
    • (2004) Int J Impot Res , vol.16 , Issue.1 SUPPL.
    • Burnett, A.L.1
  • 4
    • 0042844737 scopus 로고    scopus 로고
    • Individual cerebellar Purkinje cells express different cGMP phosphodiesterases (PDEs): In vivo phosphorylation of cGMP-specific PDE (PDE5) as an indicator of cGMP-dependent protein kinase (PKG) activation
    • M. Shimizu-Albergine, S.D. Rybalkin, I.G. Rybalkina, R. Feil, W. Wolfsgruber, F. Hofmann, J.A. Beavo Individual cerebellar Purkinje cells express different cGMP phosphodiesterases (PDEs) in vivo phosphorylation of cGMP-specific PDE (PDE5) as an indicator of cGMP-dependent protein kinase (PKG) activation J Neurosci 23 2003 6452 6459
    • (2003) J Neurosci , vol.23 , pp. 6452-6459
    • Shimizu-Albergine, M.1    Rybalkin, S.D.2    Rybalkina, I.G.3    Feil, R.4    Wolfsgruber, W.5    Hofmann, F.6    Beavo, J.A.7
  • 5
    • 3342962358 scopus 로고    scopus 로고
    • Mechanisms of action of PDE5 inhibition in erectile dysfunction
    • J.D. Corbin Mechanisms of action of PDE5 inhibition in erectile dysfunction Int J Impot Res 16 suppl 1 2004 S4 S7
    • (2004) Int J Impot Res , vol.16 , Issue.1 SUPPL.
    • Corbin, J.D.1
  • 7
    • 0242579616 scopus 로고    scopus 로고
    • Overview of phosphodiesterase 5 inhibition in erectile dysfunction
    • R.C. Rosen, J.B. Kostis Overview of phosphodiesterase 5 inhibition in erectile dysfunction Am J Cardiol 92 2003 9M 18M
    • (2003) Am J Cardiol , vol.92
    • Rosen, R.C.1    Kostis, J.B.2
  • 8
    • 0142246433 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 inhibitors: A biochemical and clinical correlation survey
    • N.N. Kim Phosphodiesterase type 5 inhibitors a biochemical and clinical correlation survey Int J Impot Res 15 suppl 5 2003 S13 S19
    • (2003) Int J Impot Res , vol.15 , Issue.5 SUPPL.
    • Kim, N.N.1
  • 9
    • 1842428108 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 inhibitor differentiation based on selectivity, pharmacokinetic, and efficacy profiles
    • A.D. Seftel Phosphodiesterase type 5 inhibitor differentiation based on selectivity, pharmacokinetic, and efficacy profiles Clin Cardiol 27 4 suppl 1 2004 I14 I19
    • (2004) Clin Cardiol , vol.27 , Issue.4 SUPPL. 1
    • Seftel, A.D.1
  • 11
    • 3042574999 scopus 로고    scopus 로고
    • Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation
    • M.A. Blount, A. Beasley, R. Zoraghi, K.R. Sekhar, E.P. Bessay, S.H. Francis, J.D. Corbin Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation Mol Pharmacol 66 2004 144 152
    • (2004) Mol Pharmacol , vol.66 , pp. 144-152
    • Blount, M.A.1    Beasley, A.2    Zoraghi, R.3    Sekhar, K.R.4    Bessay, E.P.5    Francis, S.H.6    Corbin, J.D.7
  • 12
    • 1842530387 scopus 로고    scopus 로고
    • Clinical efficacy of sildenafil in primary pulmonary hypertension: A randomized, placebo-controlled, double-blind, crossover study
    • B.K. Sastry, C. Narasimhan, N.K. Reddy, B.S. Raju Clinical efficacy of sildenafil in primary pulmonary hypertension a randomized, placebo-controlled, double-blind, crossover study J Am Coll Cardiol 43 2004 1149 1153
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1149-1153
    • Sastry, B.K.1    Narasimhan, C.2    Reddy, N.K.3    Raju, B.S.4
  • 13
    • 3142546340 scopus 로고    scopus 로고
    • Randomized study of testosterone gel as adjunctive therapy to sildenafil in hypogonadal men with erectile dysfunction who do not respond to sildenafil alone
    • R. Shabsigh, J.M. Kaufman, C. Steidle, H. Padma-Nathan Randomized study of testosterone gel as adjunctive therapy to sildenafil in hypogonadal men with erectile dysfunction who do not respond to sildenafil alone J Urol 172 2004 658 663
    • (2004) J Urol , vol.172 , pp. 658-663
    • Shabsigh, R.1    Kaufman, J.M.2    Steidle, C.3    Padma-Nathan, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.