Relationship between flavonoid structure and inhibition of farnesyl protein transferase

Natural Product Research

Volumn 18, Issue 4, 2004, Pages 349-356

  Kang, Hyun Mi ^a,b   Kim, Jong Han ^a   Lee, Mi Young ^a   Son, Kwang Hee ^a   Yang, Deok Cho ^b   Baek, Nam In ^c   Kwon, Byoung Mog ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungbuk National University   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

Cell proliferation assay; Farnesyl protein transferase; Flavonoid; Structure activity relationship

Indexed keywords

3 HYDROXYFLAVONE; 3,7 DIHYDROXYFLAVONE; 5,6 DIHYDROXY 7,3',4' TRIMETHOXYFLAVONE; 5,6,4' TRIHYDROXY 7,3' DIMETHOXYFLAVONE; 7 HYDROXYFLAVONE; ACACETIN; APIGENIN; BUTEIN; CATECHIN; CHRYSIN; FISETIN; FLAVONE; FLAVONE DERIVATIVE; FLAVONOID; GALANGIN; GENISTEIN; HISPIDULIN; HYDROXYL GROUP; ISORHAMNETIN; KAEMPFEROL; LUTEOLIN; MORIN; MYRICETIN; NARINGENIN; PHLORETIN; PROTEIN FARNESYLTRANSFERASE; QUERCETIN; RUTOSIDE; TAXIFOLIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CHEMICAL BOND; CHEMICAL REACTION; COLON CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME ASSAY; ENZYME INHIBITION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; TUMOR CELL LINE;

EID: 2942737258     PISSN: 14786419     EISSN: None     Source Type: Journal    
DOI: 10.1080/14786410310001622022     Document Type: Article

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