Interleukin-3 binding to the murine βIL-3 and human βc receptors involves functional epitopes formed by domains 1 and 4 of different protein chains

Journal of Biological Chemistry

Volumn 279, Issue 25, 2004, Pages 26500-26508

  Murphy, James M ^a,b   Ford, Sally C ^a   Olsen, Jane E ^a   Gustin, Sonja E ^a   Jeffrey, Peter D ^a   Ollis, David L ^b   Young, Ian G ^a  

^a Biology and Environment   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; DISEASE CONTROL; NEUROLOGY; SIGNAL PROCESSING; X RAY ANALYSIS;

HEMATOPOIETIC CELLS; INFLAMATORY DISEASES; T-CELLS;

BINDING ENERGY;

ASPARAGINE; EPITOPE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 3 RECEPTOR; INTERLEUKIN 5; PHENYLALANINE; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHRONIC INFLAMMATION; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; MAST CELL; MOUSE; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; SEQUENCE HOMOLOGY; T LYMPHOCYTE; ULTRACENTRIFUGATION;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; CELL DIVISION; COS CELLS; CROSS-LINKING REAGENTS; CRYSTALLOGRAPHY, X-RAY; CYTOKINE RECEPTOR COMMON BETA SUBUNIT; CYTOKINES; DIMERIZATION; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EPITOPES; FLOW CYTOMETRY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-3; INTERLEUKIN-5; KINETICS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; ULTRACENTRIFUGATION;

ANIMALIA; MURINAE;

EID: 2942729678     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402705200     Document Type: Article

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