A novel functional epitope formed by domains 1 and 4 of the human common β-subunit is involved in receptor activation by granulocyte macrophage colony-stimulating factor and interleukin 5

Journal of Biological Chemistry

Volumn 278, Issue 12, 2003, Pages 10572-10577

  Murphy, James M ^a,b   Ford, Sally C ^a   Wiedemann, Ursula M ^a   Carr, Paul D ^b   Ollis, David L ^b   Young, Ian G ^a  

^a Biology and Environment   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; INTERFACES (MATERIALS); MUTAGENESIS;

PROLIFERATION;

BIOCHEMISTRY;

EPITOPE; FIBRONECTIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 5; LIGAND; PROTEIN SUBUNIT; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 3 RECEPTOR; INTERLEUKIN 5 RECEPTOR; INTERLEUKIN RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; EXTRACELLULAR SPACE; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; CHEMISTRY; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

EPITOPES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-5; PROTEIN SUBUNITS; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-3; RECEPTORS, INTERLEUKIN-5; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0038532303     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211664200     Document Type: Article

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