Exacerbated graft-versus-host disease in Pirb-/- mice

Nature Immunology

Volumn 5, Issue 6, 2004, Pages 623-629

  Nakamura, Akira ^a   Kobayashi, Eiji ^a   Takai, Toshiyuki ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PHOSPHOTYROSINE; TETRAMER; H2 ANTIGEN; PIRA1 PROTEIN, MOUSE; PIRB PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CELL SEPARATION; CELL TRANSPLANTATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DISEASE EXACERBATION; FLOW CYTOMETRY; GRAFT VERSUS HOST REACTION; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SPLEEN CELL; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BINDING SITE; C57BL MOUSE; GENETICS; IMMUNOLOGY; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

ANIMALS; B-LYMPHOCYTES; BINDING SITES; DENDRITIC CELLS; GRAFT VS HOST DISEASE; H-2 ANTIGENS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IMMUNOLOGIC;

EID: 2942685448     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1074     Document Type: Article

References (44)

1. Kärre, K. NK cells, MHC class I molecules and the missing self. Scand. J. Immunol. 55, 221-228 (2002).
2. Cerwenka, A. & Lanier, L.L. Natural killer cells, viruses and cancer. Nat. Rev. Immunol. 1, 41-49 (2001).
3. Ravetch, J.V. & Lanier, L.L. Immune inhibitory receptors. Science 290, 84-89 (2000).
4. Shlomchik, W.D. et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 285, 412-415 (1999).
5. Shlomchik, W.D. et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 285, 412-415 (1999).
6. Heeger, P.S. T-cell allorecognition and transplant rejection: A summary and update. Am. J. Transplant. 3, 525-533 (2003).
7. Colonna, M., Nakajima, H., Navarro, F. & Lopez-Botet, M. A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells. J. Leukoc. Biol. 66, 375-381 (1999).
8. Borges, L. & Cosman, D. LIRs/ILTs/MIRs, inhibitory and stimulatory Ig-superfamily receptors expressed in myeloid and lymphoid cells. Cytokine Growth Factor Rev. 11, 209-217 (2000).
9. Long, E.O. Regulation of immune responses through inhibitory receptors. Annu. Rev. Immunol. 17, 875-904 (1999).
10. Colonna, M. TREMs in the immune system and beyond. Nat. Rev. Immunol. 3, 445-453 (2003).
11. Nakajima, H., Samaridis, J., Angman, L. & Colonna, M. Human myeloid cells express an activating ILT receptor (ILT1) that associates with Fc receptor γ-chain. J. Immunol. 162, 5-8 (1999).
12. Colonna, M. et al. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186, 1809-1818 (1997).
13. Colonna, M. et al. Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules. J. Immunol. 160, 3096-3100 (1998).
14. Chang, C.C. et al. Tolerization of dendritic cells by Ts cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat. Immunol. 3, 237-243 (2002).
15. Manavalan, J.S. et al. High expression of ILT3 and ILT4 is a general feature of tolerogenic dendritic cells. Transpl. Immunol. 11, 245-258 (2003).
16. Hayami, K. et al. Molecular cloning of a novel murine cell-surface glycoprotein homologous to killer cell inhibitory receptors. J. Biol. Chem. 272, 7320-7327 (1997).
17. Kubagawa, H., Burrows, P.D. & Cooper, M.D. A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc. Natl. Acad. Sci. USA 94, 5261-5266 (1997).
18. Yamashita, Y. et al. Genomic structures and chromosomal location of p91, a novel murine regulatory receptor family. J. Biochem. 123, 358-368 (1998).
19. Kubagawa, H. et al. Biochemical nature and cellular distribution of the paired immunoglobulin-like receptors, PIR-Aand PIR-B. J. Exp. Med. 189, 309-318 (1999).
20. Kubagawa, H. et al. Paired immunoglobulin-iike receptors of activating and inhibitory types. Curr. Top. Microbiol. Immunol. 244, 137-149 (1999).
21. Takai, T. & Ono, M. Activating and inhibitory nature of the murine paired Ig-like receptor (PIR) family. Immunol. Rev. 181, 215-222 (2001).
22. Maeda, A., Kurosaki, M. & Kurosaki, T. Paired immunoglobulin-like receptor (PIR)-A is involved in activating mast cells through its association with Fc receptor γ chain. J. Exp. Med. 188, 991-995 (1998).
23. Yamashita, Y., Ono, M. & Takai, T. Inhibitory and stimulatory functions of paired Ig-like receptor (PIR) family in RBL-2H3 cells. J. Immunol. 161, 4042-4047 (1998).
24. Ono, M., Yuasa, T., Ra, C. & Takai, T. Stimulatory function of paired immunoglobulin-like receptor-A in mast cell line by associating with subunits common to Fc receptors. J. Biol. Chem. 274, 30288-30296 (1999).
25. Bléry, M. et al. The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1. Proc. Natl. Acad. Sci. USA 95, 2446-2451 (1998).
26. Maeda, A., Kurosaki, M., Ono, M., Takai, T. & Kurosaki, T. Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal. J. Exp. Med. 187, 1355-1360 (1998).
27. -1- mice. Nat. Immunol. 3, 542-548 (2002).
28. Ho, L.H., Uehara, T., Chen. C.C., Kubagawa, H. & Cooper, M.D. Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B. Proc. Natl. Acad. Sci. USA 96, 15086-15090 (1999).
29. Liang, S., Baibakov, B. & Horuzsko, A. HLA-G inhibits the functions of murine dendritic cells via the PIR-B immune inhibitory receptor. Eur. J. Immunol. 32, 2418-2426 (2002).
30. Hogarth, P.M. Fc receptors are major mediators of antibody based inflammation in autoimmunity. Curr. Opin. Immunol. 14, 798-802 (2002).
31. Takai, T. Roles of Fc receptors in autoimmunity. Nat. Rev. Immunol. 8, 580-592 (2002).
32. Shiroishi, M. et al. Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc. Natl. Acad. Sci. USA 100, 8856-8861 (2003).
33. Hart, G., Flaishon, L., Becker-Herman, S. & Shachar, I. Ly49D receptor expressed on immature B cells regulates their IFN-γ secretion, actin polymerization, and homing. J. Immunol. 171, 4630-4638 (2003).
34. Takai, T., Li, M., Sylvestre, D., Clynes, R. & Ravetch, J.V. FcRγ chain deletion results in pleiotrophic effector cell defects. Cell 76, 519-529 (1994).
35. Pedersen, A.E., Jacoby, B.F., Skov, S. & Claesson, M.H. MHC class I is functionally associated with antigen receptors in human T and B lymphomas. Cell. Immunol. 173, 295-302 (1996).
36. c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol. Cell. Biol. 14, 4335-4341 (1994).
37. Mul, A.L., Wakao, H., O'Farrell, A.M., Harada, N. & Miyajima, A. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J. 14, 1166-1175 (1995).
38. Blazar, B.R. et al. Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-γ -dependent mechanism. J. Immunol. 171, 1272-1277 (2003).
39. Cosman, D. et al. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 7, 273-282 (1997).
40. Willcox, B.E., Thomas, L.M. & Bjorkman, P.J. Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor. Nat. Immunol. 4, 913-919 (2003).
41. Kogure, T. et al. Effect of interleukin 2 on killer cell inhibitory receptors in patients with rheumatoid arthritis. Ann. Rheum. Dis. 60, 166-169 (2001).
42. + synovial fluid T cells by NK cell receptor expression in HLA-B27-associated reactive arthritis. Int. Immunol. 14, 471-479 (2002).
43. Kollnberger, S. et al. Cell-surface expression and immune receptor recognition of HLA-B27 homodimers. Arthritis. Rheum. 46, 2972-2982 (2002).
44. Laferté, S., Loh, L.C. & Keeler, V. Monoclonal antibodies specific for human tumor-associated antigen 90K/Mac-2 binding protein: Tools to examine protein conformation and function. J. Cell. Biochem. 77, 540-559 (2000).