Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor

Arkivoc

Volumn 2004, Issue 5, 2004, Pages 312-324

  Salerno, Loredana ^a   Siracusa, Mariangela ^a   Guerrera, Francesco ^a   Romeo, Giuseppe ^a   Pittalà, Valeria ^a   Modica, Maria ^a   Mennini, Tiziana ^b   Russo, Filippo ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

1 Adrenoceptor subtypes; 5 HT1A Serotonin Receptor; 5 Phenyl 1,2,4 triazole; Triazole Ring Alkylation

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3 [5 (2 CHLOROPHENYL)] [[2 [4 (2 METHOXYPHENYL)1 PIPERAZINYL]ETHYL]THIO][1,2,4]TRIAZOLE; 3 [5 (4 CHLOROPHENYL)][2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO][1,2,4]TRIAZOLE; 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 (4 METHYLPHENYL)[1,2,4]TRIAZOLE; 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 (4 NITROPHENYL)[1,2,4]TRIAZOLE; 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 (4 PHENYLSULFONYLPHENYL)[1,2,4]TRIAZOLE; 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 (4 PROPYLOXYPHENYL)[1,2,4]TRIAZOLE; 3 [[2 [4 (2 METHOXYPHENYL)1 PIPERAZINYL]ETHYL]THIO] 5 PHENYL[1,2,4]TRIAZOLE; 3 [[2 [4 (2 NITROPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 (4 PROPYLOXYPHENYL)[1,2,4]TRIAZOLE; 3 [[2 [4 (2 NITROPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 PHENYL[1,2,4]TRIAZOLE; 4 AMINO 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 5 (4 METHYLPHENYL) 2,4 DIHYDRO 3H[1,2,4]TRIAZOLE 3 THIONE; 4 AMINO 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 5 (4 PHENYLSULFONYLPHENYL) 2,4 DIHYDRO 3H[1,2,4]TRIAZOLE 3 THIONE; 4 AMINO 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 5 PHENYL 2,4 DIHYDRO 3H[1,2,4]TRIAZOLE 3 THIONE; 4 AMINO 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 (4 METHYLPHENYL)[1,2,4]TRIAZOLE; 4 AMINO 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 (4 PHENYLSULFONYLPHENYL) 4H[1,2,4]TRIAZOLE; 4 AMINO 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO] 5 PHENYL[1,2,4]TRIAZOLE; 4 AMINO 5 (2 CHLOROPHENYL) 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO][1,2,4]TRIAZOLE; 4 AMINO 5 (2CHLOROPHENYL) 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 2,4 DIHYDRO 3H[1,2,4]TRIAZOLE 3 THIONE; 4 AMINO 5 (4 CHLOROPHENYL) 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 2,4 DIHYDRO 3H[1,2,4]TRIAZOLE 3 THIONE; 4 AMINO 5 (4 CHLOROPHENYL) 3 [[2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL]THIO][1,2,4] TRIAZOLE; 5 PHENYL[1,2,4]TRIAZOLE DERIVATIVE; ALPHA 1 ADRENERGIC RECEPTOR; PRAZOSIN; RADIOLIGAND; SEROTONIN 1A RECEPTOR; SEROTONIN RECEPTOR AFFECTING AGENT; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; NONHUMAN; RAT;

EID: 2942662141     PISSN: 14246376     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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