-
1
-
-
78650874372
-
SU11248 inhibits KIT and platelet-derived growth factor receptor β in preclinical models of human small cell lung cancer
-
Abrams, T.J., Lee, L.B., Murray, L.J., Pryer, N.K., Cherrington, J.M., 2003. SU11248 inhibits KIT and platelet-derived growth factor receptor β in preclinical models of human small cell lung cancer. Mol. Cancer Ther. 2, 471-478.
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 471-478
-
-
Abrams, T.J.1
Lee, L.B.2
Murray, L.J.3
Pryer, N.K.4
Cherrington, J.M.5
-
2
-
-
0037879057
-
The interface between Erb and non-Erb receptors in tumor invasion: Clinical implications and opportunities for target discovery
-
Alaoui-Jamali, M.A., Qiang, H., 2003. The interface between Erb and non-Erb receptors in tumor invasion: clinical implications and opportunities for target discovery. Drug Resist. Update 6, 95-107.
-
(2003)
Drug Resist. Update
, vol.6
, pp. 95-107
-
-
Alaoui-Jamali, M.A.1
Qiang, H.2
-
3
-
-
85030877971
-
B153 Molecular mechanism of Gleevec resistance revealed by the mutagenesis of BCR/ABL gene
-
abstract B153
-
Azam, M., Daley, G.Q., 2003. B153 Molecular mechanism of Gleevec resistance revealed by the mutagenesis of BCR/ABL gene. Clin. Cancer Res. 9 (16 Suppl.), 6174S (abstract B153).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Azam, M.1
Daley, G.Q.2
-
4
-
-
0037459344
-
Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL
-
Azam, M., Latek, R.R., Daley, G.Q., 2003. Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL. Cell 112, 831-843.
-
(2003)
Cell
, vol.112
, pp. 831-843
-
-
Azam, M.1
Latek, R.R.2
Daley, G.Q.3
-
5
-
-
85030886746
-
Characterization of a novel class of aurora-2 kinase inhibitors
-
abstract A12
-
Bashyam, S., Warner, S.L., Vankayalapati, H., et al., 2003. Characterization of a novel class of aurora-2 kinase inhibitors. Clin. Cancer Res. 9 (16 Suppl.), 6071S-6072S (abstract A12).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Bashyam, S.1
Warner, S.L.2
Vankayalapati, H.3
-
6
-
-
8944261743
-
Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: Consensus recommendations
-
Beck, W.T., Grogan, T.M., Willman, C.L., et al., 1996. Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. Cancer Res. 56, 3010-3020.
-
(1996)
Cancer Res.
, vol.56
, pp. 3010-3020
-
-
Beck, W.T.1
Grogan, T.M.2
Willman, C.L.3
-
7
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
Bergers, G., Song, S., Meyer-Morse, N., Bergsland, E., Hanahan, D., 2003. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J. Clin. Invest. 111, 1287-1295.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
Bergsland, E.4
Hanahan, D.5
-
8
-
-
0029999404
-
How to probe clinical tumour samples for P-glycoprotein and multidrug-resistance-associated protein
-
Broxterman, H.J., Lankelma, J., Pinedo, H.M., 1996. How to probe clinical tumour samples for P-glycoprotein and multidrug-resistance-associated protein. Eur. J. Cancer 32A, 1024-1033.
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 1024-1033
-
-
Broxterman, H.J.1
Lankelma, J.2
Pinedo, H.M.3
-
9
-
-
0038713666
-
Resistance to cytotoxic and anti-angiogenic agents: Similarities and differences
-
Broxterman, H.J., Lankelma, J., Hoekman, K., 2003. Resistance to cytotoxic and anti-angiogenic agents: similarities and differences. Drug Resist. Update 6, 111-127.
-
(2003)
Drug Resist. Update
, vol.6
, pp. 111-127
-
-
Broxterman, H.J.1
Lankelma, J.2
Hoekman, K.3
-
10
-
-
0642276783
-
Epidermal growth factor receptor overexpression: The importance of context
-
Carbone, D.P., 2003. Epidermal growth factor receptor overexpression: the importance of context. J. Clin. Oncol. 21, 4268-4269.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 4268-4269
-
-
Carbone, D.P.1
-
11
-
-
0037699294
-
Strategies to target HER2/neu overexpression for cancer therapy
-
Chen, J.-S., Lan, K., Hung, M.-C., 2003. Strategies to target HER2/neu overexpression for cancer therapy. Drug Resist. Update 6, 129-136.
-
(2003)
Drug Resist. Update
, vol.6
, pp. 129-136
-
-
Chen, J.-S.1
Lan, K.2
Hung, M.-C.3
-
12
-
-
85030878015
-
A novel consensus motif in fibronectin mediates dipeptidyl peptidase IV adhesion and metastasis
-
abstract B188
-
Cheng, H.-C., Abdel-Ghany, M., Pauli, B., 2003. A novel consensus motif in fibronectin mediates dipeptidyl peptidase IV adhesion and metastasis. Clin. Cancer Res. 9 (16 Suppl.), 6182S-6183S (abstract B188).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Cheng, H.-C.1
Abdel-Ghany, M.2
Pauli, B.3
-
13
-
-
85030876185
-
Structure-based design and X-ray crystallographic analysis of a potent and selective Src tyrosine kinase inhibitor for the treatment of cancer
-
abstract A5
-
Dalgarno, D.C., Bohacek, R., Stehle, T., et al., 2003. Structure-based design and X-ray crystallographic analysis of a potent and selective Src tyrosine kinase inhibitor for the treatment of cancer. Clin. Cancer Res. 9 (16 Suppl.), 6070S (abstract A5).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Dalgarno, D.C.1
Bohacek, R.2
Stehle, T.3
-
14
-
-
24844439718
-
ZM447439, a novel Aurora kinase inhibitor, prevents chromosome alignment and compromises spindle checkpoint function in human cells
-
abstract A279
-
Ditchfield, C., Johnson, V.L., Taylor, S.S., et al., 2003a. ZM447439, a novel Aurora kinase inhibitor, prevents chromosome alignment and compromises spindle checkpoint function in human cells. Clin. Cancer Res. 9 (16 Suppl.), 6138S (abstract A279).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Ditchfield, C.1
Johnson, V.L.2
Taylor, S.S.3
-
15
-
-
0013057087
-
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
-
Ditchfield, C., Johnson, V.L., Tighe, A., et al., 2003b. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J. Cell Biol. 161, 267-280.
-
(2003)
J. Cell Biol.
, vol.161
, pp. 267-280
-
-
Ditchfield, C.1
Johnson, V.L.2
Tighe, A.3
-
16
-
-
0035735754
-
Role of mitogen-activated kinases in the response of tumor cells to chemotherapy
-
Fan, M., Chambers, T.C., 2001. Role of mitogen-activated kinases in the response of tumor cells to chemotherapy. Drug Resist. Update 4, 253-267.
-
(2001)
Drug Resist. Update
, vol.4
, pp. 253-267
-
-
Fan, M.1
Chambers, T.C.2
-
17
-
-
0036815597
-
P53 as a therapeutic target: Unresolved issues on the road to cancer therapy targeting mutant p53
-
Fojo, T., 2002. P53 as a therapeutic target: unresolved issues on the road to cancer therapy targeting mutant p53. Drug Resist. Update 5, 209-216.
-
(2002)
Drug Resist. Update
, vol.5
, pp. 209-216
-
-
Fojo, T.1
-
18
-
-
0842290920
-
New directions in cancer research 2003: Technological advances in biology, drug resistance, and molecular pharmacology
-
Franks, M.E., Macpherson, G.R., Lepper, E.R., Figg, W.D., Sparreboom, A., 2003. New directions in cancer research 2003: technological advances in biology, drug resistance, and molecular pharmacology. Drug Resist. Update 6, 301-375.
-
(2003)
Drug Resist. Update
, vol.6
, pp. 301-375
-
-
Franks, M.E.1
Macpherson, G.R.2
Lepper, E.R.3
Figg, W.D.4
Sparreboom, A.5
-
19
-
-
0012381722
-
A multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small lung cancer (The IDEAL 1 Trial)
-
Fukuoa, M., Yano, S., Giaccone, G., et al., 2003. A multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small lung cancer (The IDEAL 1 Trial). J. Clin. Oncol. 21, 2237-2246.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2237-2246
-
-
Fukuoa, M.1
Yano, S.2
Giaccone, G.3
-
20
-
-
0036814435
-
Clinical cancer research 2002: New agents and therapies
-
Gietema, J.A., de Vries, E.G.E., 2002. Clinical cancer research 2002: new agents and therapies. Drug Resist. Update 5, 192-203.
-
(2002)
Drug Resist. Update
, vol.5
, pp. 192-203
-
-
Gietema, J.A.1
De Vries, E.G.E.2
-
21
-
-
85030874569
-
Combination therapy of inhibitors of the epidermal growth factor/ vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition
-
abstract A88
-
Goudar, R., Keir, S., Hjelmeland, M., et al., 2003. Combination therapy of inhibitors of the epidermal growth factor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition. Clin. Cancer Res. 9 (16 Suppl.), 6090S (abstract A88).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Goudar, R.1
Keir, S.2
Hjelmeland, M.3
-
22
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., Weinberg, R.A., 2000. The hallmarks of cancer. Cell 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
23
-
-
0037434981
-
Disease proteomics
-
Hanash, S., 2003. Disease proteomics. Nature 422, 226-232.
-
(2003)
Nature
, vol.422
, pp. 226-232
-
-
Hanash, S.1
-
24
-
-
0344626925
-
A myristoyl/phosphotyrosine switch regulates c-Abl
-
Hantschel, O., Nagar, B., Guettler, S., et al., 2003. A myristoyl/phosphotyrosine switch regulates c-Abl. Cell 112, 845-857.
-
(2003)
Cell
, vol.112
, pp. 845-857
-
-
Hantschel, O.1
Nagar, B.2
Guettler, S.3
-
25
-
-
0036216651
-
Unraveling the complexities of the Raf/MAPkinase pathway for pharmacological intervention
-
Herrera, R., Sebolt-Leopold, J.S., 2002. Unraveling the complexities of the Raf/MAPkinase pathway for pharmacological intervention. Trends Mol. Med. 8, S27-S31.
-
(2002)
Trends Mol. Med.
, vol.8
-
-
Herrera, R.1
Sebolt-Leopold, J.S.2
-
26
-
-
0347364778
-
Targeting the epidermal growth factor receptor in non-small cell lung cancer
-
Herbst, R., Bunn, Jr., P.A., 2003. Targeting the epidermal growth factor receptor in non-small cell lung cancer. Clin. Cancer Res. 9, 5813-5824.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5813-5824
-
-
Herbst, R.1
Bunn Jr., P.A.2
-
27
-
-
0347364770
-
Is KIT an important therapeutic target in small cell lung cancer?
-
Heinrich, M.C., 2003. Is KIT an important therapeutic target in small cell lung cancer? Clin. Cancer Res. 9, 5825-5828.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5825-5828
-
-
Heinrich, M.C.1
-
28
-
-
0142119289
-
Epidermal growth factor receptor in non-small cell lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis
-
Hirsch, F., Varella-Garcia, M., Bunn, P.A., 2003. Epidermal growth factor receptor in non-small cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J. Clin. Oncol. 21, 3798-3807.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 3798-3807
-
-
Hirsch, F.1
Varella-Garcia, M.2
Bunn, P.A.3
-
29
-
-
0842304140
-
Vascular remodeling marks tumors that recur during chronic suppression of angiogenesis
-
Huang, J., Soffer, S.Z., Kim, E.S., et al., 2004. Vascular remodeling marks tumors that recur during chronic suppression of angiogenesis. Mol. Cancer Res. 2, 36-42.
-
(2004)
Mol. Cancer Res.
, vol.2
, pp. 36-42
-
-
Huang, J.1
Soffer, S.Z.2
Kim, E.S.3
-
30
-
-
9144230676
-
Phase II study of imatinib in patients with small cell lung cancer
-
Johnson, B.E., Fischer, T., Fischer, B., et al., 2003. Phase II study of imatinib in patients with small cell lung cancer. Clin. Cancer Res. 9, 5880-5887.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5880-5887
-
-
Johnson, B.E.1
Fischer, T.2
Fischer, B.3
-
31
-
-
24744469113
-
Final evaluation of Tarceva (Erlotinib) in combination with FOLFOX4 in patients with solid tumors
-
abstract A108
-
Jones, R.J., Hanauske, A., Diaz-Rubio, E., et al., 2003. Final evaluation of Tarceva (Erlotinib) in combination with FOLFOX4 in patients with solid tumors. Clin. Cancer Res. 9 (16 Suppl.), 6095S (abstract A108).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Jones, R.J.1
Hanauske, A.2
Diaz-Rubio, E.3
-
32
-
-
0038713433
-
Dipeptidyl peptidase IV overexpression induces up-regulation of E-cadherin and tissue inhibitors of metalloproteinases, resulting in decreased invasive potential in ovarian carcinoma cells
-
Kajiyama, H., Kikkawa, F., Khin, E., Shibata, K., Ino, K., Mizutani, S., 2003. Dipeptidyl peptidase IV overexpression induces up-regulation of E-cadherin and tissue inhibitors of metalloproteinases, resulting in decreased invasive potential in ovarian carcinoma cells. Cancer Res. 63, 2278-2283.
-
(2003)
Cancer Res.
, vol.63
, pp. 2278-2283
-
-
Kajiyama, H.1
Kikkawa, F.2
Khin, E.3
Shibata, K.4
Ino, K.5
Mizutani, S.6
-
33
-
-
0141484615
-
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
-
Kamal, A., Thao, L., Sensintaffar, J., et al., 2003. A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 425, 407-410.
-
(2003)
Nature
, vol.425
, pp. 407-410
-
-
Kamal, A.1
Thao, L.2
Sensintaffar, J.3
-
34
-
-
0037087585
-
Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors
-
Kuenen, B.C., Rosen, L., Smit, E.F., et al., 2002. Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors. J. Clin. Oncol. 20, 1657-1667.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1657-1667
-
-
Kuenen, B.C.1
Rosen, L.2
Smit, E.F.3
-
35
-
-
85030882666
-
Targeting BRAF by siRNA in human melanoma
-
abstract A111
-
Liang, Y.Z., Gawad, C., Azorsa, D., et al., 2003. Targeting BRAF by siRNA in human melanoma. Clin. Cancer Res. 9 (16 Suppl.), 6096S (abstract A111).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Liang, Y.Z.1
Gawad, C.2
Azorsa, D.3
-
36
-
-
3042825803
-
Skin toxicity is not a clinically prognostic marker for tumor response to gefitinib (Iressa, ZD1839) in pre-treated patients with advanced non-small cell lung cancer
-
abstract A70
-
Lynch, T., Ranson, M., Herbst, R., et al., 2003. Skin toxicity is not a clinically prognostic marker for tumor response to gefitinib (Iressa, ZD1839) in pre-treated patients with advanced non-small cell lung cancer. Clin. Cancer Res. 9 (16 Suppl.), 6086S (abstract A70).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Lynch, T.1
Ranson, M.2
Herbst, R.3
-
37
-
-
0242490063
-
Abrogation of E-cadherin-mediated adhesion induces tumor cell invasion in human skin-like organotypic culture
-
Margulis, A., Fusenig, N., Hashimoto, K., Hanakawa, Y., Garlick, J.A., 2003. Abrogation of E-cadherin-mediated adhesion induces tumor cell invasion in human skin-like organotypic culture. J. Investig. Dermatol. 121, 1182-1190.
-
(2003)
J. Investig. Dermatol.
, vol.121
, pp. 1182-1190
-
-
Margulis, A.1
Fusenig, N.2
Hashimoto, K.3
Hanakawa, Y.4
Garlick, J.A.5
-
38
-
-
85030883042
-
Mechanism of action of pre-operative trastuzumab in patients with primary operable breast tumors overexpressing HER2
-
abstract B270
-
Menard, S., Gennari, R., Fagnoni, F., et al., 2003. Mechanism of action of pre-operative trastuzumab in patients with primary operable breast tumors overexpressing HER2. Clin. Cancer Res. 9 (16 Suppl.), 6203S (abstract B270).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Menard, S.1
Gennari, R.2
Fagnoni, F.3
-
39
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
Mendelsohn, J., Baselga, J., 2003. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J. Clin. Oncol. 21, 2787-2799.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
40
-
-
0141520276
-
Drug resistance and the microenvironment: Nature and nurture
-
Morin, P.J., 2003. Drug resistance and the microenvironment: nature and nurture. Drug Resist. Update 6, 169-172.
-
(2003)
Drug Resist. Update
, vol.6
, pp. 169-172
-
-
Morin, P.J.1
-
41
-
-
0344626926
-
Structural basis for the autoinhibition of c-Abl tyrosine kinase
-
Nagar, B., Hantschel, O., Young, M.A., et al., 2003. Structural basis for the autoinhibition of c-Abl tyrosine kinase. Cell 112, 859-871.
-
(2003)
Cell
, vol.112
, pp. 859-871
-
-
Nagar, B.1
Hantschel, O.2
Young, M.A.3
-
42
-
-
0033150335
-
Hsp90 as an anticancer target
-
Neckers, L., Mimnaugh, E., Schulte, T.W., 1999. Hsp90 as an anticancer target. Drug Resist. Update 2, 165-172.
-
(1999)
Drug Resist. Update
, vol.2
, pp. 165-172
-
-
Neckers, L.1
Mimnaugh, E.2
Schulte, T.W.3
-
43
-
-
10744226821
-
Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays
-
Nishizuka, S., Charboneau, L., Young, L., 2003. Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays. Proc. Natl. Acad. Sci. U.S.A. 100, 14229-14234.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 14229-14234
-
-
Nishizuka, S.1
Charboneau, L.2
Young, L.3
-
44
-
-
0345359585
-
An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukaemia patients
-
O'Farrell, A.-M., Foran, J.M., Fiedler, W., 2003. An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukaemia patients. Clin. Cancer Res. 9, 5465-5476.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5465-5476
-
-
O'Farrell, A.-M.1
Foran, J.M.2
Fiedler, W.3
-
45
-
-
0036718796
-
Clinical proteomics: Translating benchside promise into bedside reality
-
Petricoin, E.F., Zoon, K.C., Kohn, E.C., Barrett, J.C., Liotta, L.A., 2003. Clinical proteomics: translating benchside promise into bedside reality. Nat. Rev. Drug Discov. 1, 683-695.
-
(2003)
Nat. Rev. Drug Discov.
, vol.1
, pp. 683-695
-
-
Petricoin, E.F.1
Zoon, K.C.2
Kohn, E.C.3
Barrett, J.C.4
Liotta, L.A.5
-
46
-
-
2942563441
-
Phase II study of BAY 43-9006 using the randomized discontinuation design in patients with advanced refractory cancer
-
abstract C254
-
Ratain, M.J., Stadler, W., Smith, M., et al., 2003. Phase II study of BAY 43-9006 using the randomized discontinuation design in patients with advanced refractory cancer. Clin. Cancer Res. 9 (16 Suppl.), 6265S-6266S (abstract C254).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Ratain, M.J.1
Stadler, W.2
Smith, M.3
-
47
-
-
24844463592
-
Receptor-based targeting strategy for bombesin receptor expressing cancers
-
abstract B236
-
Safavy, A., McChesnet, J.D., Ainsworth, S.K., Helson, L., 2003. Receptor-based targeting strategy for bombesin receptor expressing cancers. Clin. Cancer Res. 9 (16 Suppl.), 6194S (abstract B236).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Safavy, A.1
McChesnet, J.D.2
Ainsworth, S.K.3
Helson, L.4
-
48
-
-
0036462583
-
EGF receptor targeting in therapy-resistant human tumors
-
Schmidt, M., Lichtner, R.B., 2002. EGF receptor targeting in therapy-resistant human tumors. Drug Resist. Update 5, 11-18.
-
(2002)
Drug Resist. Update
, vol.5
, pp. 11-18
-
-
Schmidt, M.1
Lichtner, R.B.2
-
49
-
-
2542612580
-
Tumor markers. From laboratory to clinical utility
-
Schrohl, A.-S., Holten-Andersen, M., Sweep, F., Schmitt, M., Harbeck, N., Foekens, J., Brünner, N., 2003. Tumor markers. From laboratory to clinical utility. Mol. Cell. Proteomics 2, 378-387.
-
(2003)
Mol. Cell. Proteomics
, vol.2
, pp. 378-387
-
-
Schrohl, A.-S.1
Holten-Andersen, M.2
Sweep, F.3
Schmitt, M.4
Harbeck, N.5
Foekens, J.6
Brünner, N.7
-
50
-
-
85030887892
-
Cellular metabolism of Poly-L-glutamic acid-palitaxel (Xyotax) is mediated in part by lysosomal cathepsin B
-
abstract C237
-
Shaffer, S.A., Baker Lee, C., Lai, M.S., et al., 2003. Cellular metabolism of Poly-L-glutamic acid-palitaxel (Xyotax) is mediated in part by lysosomal cathepsin B. Clin. Cancer Res. 9 (16 Suppl.), 6261S (abstract C237).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Shaffer, S.A.1
Baker Lee, C.2
Lai, M.S.3
-
51
-
-
0141484480
-
Remodeling of the extracellular matrix thruogh overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells
-
Sherman-Baust, C.A., Weeraratna, A.T., Rangel, L.B.A., et al., 2003. Remodeling of the extracellular matrix thruogh overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells. Cancer Cell 3, 377-386.
-
(2003)
Cancer Cell
, vol.3
, pp. 377-386
-
-
Sherman-Baust, C.A.1
Weeraratna, A.T.2
Rangel, L.B.A.3
-
52
-
-
2942619658
-
Pulsatile administration of the EGFR receptor inhibitor gefitinib (Iressa, ZD1839) is significantly more effective than continuous dosing for sensitizing tumors to Taxol
-
abstract A83
-
Solit, D.B., She, Y., Moasser, M., et al., 2003. Pulsatile administration of the EGFR receptor inhibitor gefitinib (Iressa, ZD1839) is significantly more effective than continuous dosing for sensitizing tumors to Taxol. Clin. Cancer Res. 9 (16 Suppl.), 6089S (abstract A83).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Solit, D.B.1
She, Y.2
Moasser, M.3
-
53
-
-
85030887664
-
Tumor-stroma interaction: Positive feedback regulation of EMMPRIN expression and MMP-dependent generation of soluble EMMPRIN
-
abstract B194
-
Tang, Y., Kesavan, P., Nakada, M.T., Yan, L., 2003. Tumor-stroma interaction: positive feedback regulation of EMMPRIN expression and MMP-dependent generation of soluble EMMPRIN. Clin. Cancer Res. 9 (16 Suppl.), 6184S (abstract B194).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Tang, Y.1
Kesavan, P.2
Nakada, M.T.3
Yan, L.4
-
54
-
-
85030874465
-
Preclinical activity of AEE788, a potent new inhibitor of the ErbB and VEGF receptor kinases. In vivo profile of AEE788
-
abstract A87
-
Traxler, P., Allegrini, P.R., Brandt, R., 2003. Preclinical activity of AEE788, a potent new inhibitor of the ErbB and VEGF receptor kinases. In vivo profile of AEE788. Clin. Cancer Res. 9 (16 Suppl.), 6090S (abstract A87).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Traxler, P.1
Allegrini, P.R.2
Brandt, R.3
-
55
-
-
0038037108
-
Role of Jun and Jun kinase in resistance of cancer cells to therapy
-
Vasilevskaya, I., O'Dwyer, P.J., 2003. Role of Jun and Jun kinase in resistance of cancer cells to therapy. Drug Resist. Update 6, 147-156.
-
(2003)
Drug Resist. Update
, vol.6
, pp. 147-156
-
-
Vasilevskaya, I.1
O'Dwyer, P.J.2
-
56
-
-
0345600892
-
Resistance to imatinib (Glivec): Update on clinical mechanisms
-
Weisberg, E., Griffin, J.D., 2003. Resistance to imatinib (Glivec): update on clinical mechanisms. Drug Resist. Update 6, 231-238.
-
(2003)
Drug Resist. Update
, vol.6
, pp. 231-238
-
-
Weisberg, E.1
Griffin, J.D.2
-
57
-
-
0036968347
-
Activation of the PI3K/Akt pathway and chemotherapeutic resistance
-
West, K.A., Castillo, S.S., Dennis, P.A., 2002. Activation of the PI3K/Akt pathway and chemotherapeutic resistance. Drug Resist. Update 5, 234-258.
-
(2002)
Drug Resist. Update
, vol.5
, pp. 234-258
-
-
West, K.A.1
Castillo, S.S.2
Dennis, P.A.3
-
58
-
-
16244423389
-
BAY 43-9006 exhibits broad spectrum anti-tumor activity and targets raf/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
abstract A78
-
Wilhelm, S., Carter, C., Tang, L., et al., 2003. BAY 43-9006 exhibits broad spectrum anti-tumor activity and targets raf/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Clin. Cancer Res. 9 (16 Suppl.), 6088S (abstract A78).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.16 SUPPL.
-
-
Wilhelm, S.1
Carter, C.2
Tang, L.3
-
59
-
-
0345707575
-
The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of Akt in ErbB2 overexpressing breast cancer cells
-
Xu, W., Yuan, X., Jung, Y.J., 2003. The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of Akt in ErbB2 overexpressing breast cancer cells. Cancer Res. 63, 7777-7784.
-
(2003)
Cancer Res.
, vol.63
, pp. 7777-7784
-
-
Xu, W.1
Yuan, X.2
Jung, Y.J.3
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