Activation and up-regulation of nitric oxide synthase in human umbilical vein endothelial cells by polycyclic aromatic hydrocarbons

Toxicology Letters

Volumn 151, Issue 2, 2004, Pages 367-374

  Li, Ching Hao ^a   Lee, Chen Chen ^a   Cheng, Yu Wen ^b   Juang, Hwe Ann ^a   Kang, Jaw Jou ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Ca2+; endothelial nitric oxide synthase; Endothelium; eNOS; human umbilical vein endothelial cells; HUVECs; NO; PAHs; Polycyclic aromatic hydrocarbons; polycyclic aromatic hydrocarbons

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CYTOCHROME P450 INHIBITOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FLUORANTHENE; FLUORENE; MESSENGER RNA; NAPHTHALENE; NICKEL CHLORIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; POLYCYCLIC AROMATIC HYDROCARBON; PROADIFEN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME REGULATION; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UMBILICAL VEIN; UPREGULATION;

CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENVIRONMENTAL POLLUTANTS; ENZYME ACTIVATION; HUMANS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; POLYCYCLIC HYDROCARBONS, AROMATIC; RNA, MESSENGER; UMBILICAL VEINS; UP-REGULATION;

EID: 2942616784     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.03.003     Document Type: Article

References (35)

1. 2+/calmodulin-dependent protein kinase II/janus kinase 2-dependent pathway. Arterio. Thromb. Vasc. Biol. 21:2001;1571-1576
2. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159
3. Day B.W., Sahali Y., Hutchins D.A., Wildschutte M., Pastorelli R., Nguyen T.T., Naylor S., Skipper P.L., Wishnok J.S., Tannenbaum S.R. Fluoranthene metabolism: human and rat liver microsomes display different stereoselective formation of the trans-2, 3-dihydrodiol. Chem. Res. Toxicol. 5:1992;779-786
4. DeLisser H.M., Newman P.J., Albelda S.M. Platelet endothelial cell adhesion molecule (CD31). Cur. Topics Microbiol. Immunol. 184:1993;37-45
5. Diaz-Sanchez D. The role of diesel exhaust particles and their associated polyaromatic hydrocarbons in the induction of allergic airway disease. Allergy. 52(38 Suppl):1997;52-58
6. Förstermann U., Boissel J.P., Kleinert H. Expressional control of the "constitutive" isoforms of nitric oxide synthase (NOS I and NOS III). FASEB J. 12:1998;773-790
7. Govers R., Raberlink T.J. Cellular regulation of endothelial nitric oxide synthase. Am. J. Physiol. Renal Physiol. 280:2001;F193-F206
8. 2+ influx and the formation of the endothelium-derived relaxation mediated by a G protein. Eur. J. Pharmacol. 225:1992;43-49
9. Gustavsson P., Alfredsson L., Brunnberg H., Hammar N., Jakobsson R., Reuterwall C., Ostlin P. Myocardial infarction among male bus, taxi, and lorry drivers in middle Sweden. Occup. Environ. Med. 53:1996;235-240
10. Gustavsson P., Plato N., Hallqvist J., Hogstedt C., Lewne M., Reuterwall C., Scheele P. A population-based case-referent study of myocardial infarction and occupational exposure to motor exhaust, other combustion products, organic solvents, lead, and dynamite. Epidemiology. 12:2001;222-228
11. Hirata K., Miki N., Kuroda Y., Sakoda T., Kawashima S., Yokoyama M. Low concentration of oxidized low-density lipoprotein and lysophosphatidylcholine upregulate constitutive nitric oxide synthase mRNA expression in bovine aortic endothelial cells. Circ. Res. 76:1995;958-962
12. Hughes A.D., Schachter M. Multiple pathways for entry of calcium and other divalent cations in a vascular smooth muscle cell line (A7r5). Cell Calcium. 15:1994;317-330
13. Jaffe E.A., Nachman R.L., Becker C.G., Minick C.R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52:1973;2745-2756
14. + channel. Am. J. Physiol. 275:1998;C848-C856
15. Kang J.J., Cheng Y.W. Polycyclic aromatic hydrocarbons induced vasorelaxation through induction of nitric oxide formation in endothelium of rat aorta. Toxicol. Lett. 93:1997;39-45
16. Krieger J.A., Davila D.R., Lytton J., Born J.L., Burchiel S.W. Inhibition of sarcoplasmic/endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons in HPB-ALL human T cells and other tissues. Toxicol. Appl. Pharmacol. 133:1995;102-108
17. Lee C.C., Kang J.J. Extract of motorcycle exhaust particles induced macrophages apoptosis by calcium-dependent manner. Chem. Res. Toxicol. 15:2002;1534-1542
18. Lutz C.T., Browne G., Petzold C.R. Methylcholanthrene causes increased thymocyte apoptosis. Toxicology. 128:1998;151-167
19. Malek A.M., Jiang L., Lee I., Sessa W.C., Izumo S., Alper S.L. Induction of nitric oxide synthase mRNA by shear stress requires intracellular calcium and G-protein signals and is modulated by PI3 kinase. Biochem. Biophys. Res. Commun. 254:1999;231-242
20. Mastrangelo G., Fadda E., Marzia V. Polycyclic aromatic hydrocarbons and cancer in man. Environ. Health Perspect. 104:1996;1166-1170
21. Michel T., Feron O. Nitric oxide synthases: which, where, how, and why. J. Clin. Invest. 100:1997;2146-2152
22. Mounho B.J., Burchiel S.W. Alterations in human B cell calcium homeostasis by polycyclic aromatic hydrocarbons: possible associations with cytochrome P450 metabolism and increased protein tyrosine phosphorylation. Toxicol. Appl. Pharmacol. 149:1998;80-89
23. Navarro-Antoín J., Rey-Campos J., Lamas S. Transcriptional induction of endothelial nitric oxide gene by cyclosporine A. A role for activator protein-1. J. Biol. Chem. 275:2000;3075-3080
24. Parrish A.R., Fisher R., Bral C.M., Burghardt R.C., Gandofi A.J., Brendel K., Ramos K.S. Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver and kidney slices. Toxicol. Appl. Pharmacol. 152:1998;302-308
25. Philips D.H. Polycyclic aromatic hydrocarbons in the diet. Mutat. Res. 443:1999;139-147
26. Ramasamy S., Parthasarathy S., Harrison D.G. Regulation of endothelial nitric oxide synthase gene expression by oxidized linoleic acid. J. Lipid Res. 39:1998;268-276
27. Rummel A.M., Trosko J.E., Wilson M.R., Upham B.L. Polycyclic aromatic hydrocarbons with bay-like regions inhibited gap junctional intercellular communication and stimulated MAPK activity. Toxicol. Sci. 49:1999;232-240
28. Sadler J.E. von Willebrand factor. J. Biol. Chem. 266:1991;22777-22780
29. Sonveaux P., Brouet A., Havaux X., Gregoire V., Dessy C., Balligand J.L., Feron O. Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implication for tumor radiotherapy. Cancer Res. 63:2003;1012-1019
30. 2+ in the MCF-10A human mammary epithelial cell line by carcinogenic polycyclic aromatic hydrocarbons. Mol. Carcinogen. 25:1999;48-54
31. Thirman M.J., Albrecht J.H., Krueger M.A., Erickson R.R., Cherwitz D.L., Park S.S., Gelboin H.V., Holtzman J.L. Induction of cytochrome CYP1A1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis. Proc. Natl. Acad. Sci. USA. 91:1994;5397-5401
32. Whorton A.R., Simonds D.B., Plantadosi C.A. Regulation of nitric oxide synthesis by oxygen in vascular endothelial cells. Am. J. Physiol. 272:1997;L1161-L1166
33. Xiao Z., Zhang Z., Diamond S.L. Shear stress induction of the endothelial nitric oxide synthase gene is calcium-dependent but not calcium-activated. J. Cell Physiol. 171:1997;205-211
34. Zhang Y., Ramos K.S. The induction of proliferation vascular smooth muscle cell phenotypes by benzo(a)pyrene does not involved mutational activation of ras genes. Mutat. Res. 373:1997;285-292
35. Zheng J., Bird I.M., Melsaether A.N., Magness R.R. Activation of the mitogen-activated protein kinase cascade is necessary but not sufficient for basic fibroblast growth factor- and epidermal growth factor-stimulated expression of endothelial nitric oxide synthase in ovine fetoplacental artery endothelial cells. Endocrinology. 140:1999;1399-1407