Binding modes of 6,7 di-substituted 4-anilinoquinoline-3-carbonitriles to EGFR

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 13, 2004, Pages 3397-3400

  Akula, Nagaraju ^a   Bhalla, Jag ^b   Sridhar, Jayalakshmi ^a   Pattabiraman, Nagarajan ^a,b  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

Author keywords

Docking; EGFR; Epidermal growth factor receptor; Reversible and irreversible inhibitors

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HYDROGEN; LIGAND; QUINOLINE DERIVATIVE; THIOL DERIVATIVE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL INTERACTION; CORRELATION ANALYSIS; COVALENT BOND; DRUG RECEPTOR BINDING; DRUG SCREENING; HYDROGEN BOND; IN VITRO STUDY; LIGAND BINDING; MODEL;

BINDING SITES; ENZYME INHIBITORS; HYDROGEN BONDING; LIGANDS; NITRILES; QUINOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 2942594490     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.04.080     Document Type: Article

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