Biomarkers of hypoxic brain injury in the neonate

Clinics in Perinatology

Volumn 31, Issue 1, 2004, Pages 107-116

  Buonocore, Giuseppe ^a   Perrone, Serafina ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; BIOLOGICAL MARKER; CALCIUM; CYTOCHROME C; CYTOKINE; IRON; LIPID;

APOPTOSIS; BRAIN INJURY; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CYTOKINE RELEASE; DISEASE MARKER; DNA REPAIR; ENZYME SUBSTRATE; FENTON REACTION; HUMAN; HYPOXIA; IRON KINETICS; LIPID PEROXIDATION; NEUROTRANSMITTER RELEASE; NEWBORN; NEWBORN PERIOD; OXIDATION REDUCTION REACTION; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PERINATAL ASPHYXIA; PERINATAL INFECTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW;

ACTIVINS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BIOLOGICAL MARKERS; BRAIN DAMAGE, CHRONIC; FETAL DISEASES; FETAL HYPOXIA; FREE RADICALS; HUMANS; HYPOXIA, BRAIN; HYPOXIA-ISCHEMIA, BRAIN; INFECTION; INHIBIN-BETA SUBUNITS; IRON; NERVE TISSUE PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; SYNAPTOSOMES;

EID: 2942587044     PISSN: 00955108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clp.2004.03.008     Document Type: Review

References (57)

1. Volpe J.J. Neurology of the newborn. 4th edition:2001;Saunders, Philadelphia
2. Doyle L.W., Betheras F.R., Ford G.W., Davis N.M., Callanan C. Survival, cranial ultrasound and cerebral palsy in very low birthweight infants: 1980s versus 1990s. J Paediatr Child Health. 36:2000;7-12
3. Perlman J.M. Interventions for perinatal hypoxic-ischemic encephalopathy. Pediatrics. 100:1997;1004-1014
4. Robertson C.M., Finer N.N. Long-term follow-up of term neonates with perinatal asphyxia. Clin Perinatol. 20:1993;483-500
5. Mishra O.P., Delivoria-Papadopoulos M. Cellular mechanisms of hypoxic injury in the developing brain. Brain Res Bull. 48:1999;233-238
6. Turrens J.F., Alexandre A., Lehninger A.L. Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. Arch Biochem Biophys. 237:1985;408-414
7. Carden D.L., Granger D.N. Pathophysiology of ischemia-reperfusion injury. J Pathol. 190:2000;255-266
8. Saliba E., Henrot A. Inflammatory mediators and neonatal brain damage. Biol Neonate. 79:2001;224-227
9. Buonocore G., Zani S., Sargentini I., Gioia D., Signorini C., Bracci R. Hypoxia-induced free iron release in the red cells of newborn infants. Acta Paediatr. 87:1998;77-81
10. Buonocore G., Zani S., Perrone S., Caciotti B., Bracci R. Intraerytrocyte nonprotein-bound iron and plasma malondialdehyde in the hypoxic newborn. Free Radic Biol Med. 25:1998;770-776
11. Buonocore G., Perrone S., Longini M., Vezzosi P., Bracci R. Total hydroperoxide and advanced oxidation protein products in preterm hypoxic babies. Pediatr Res. 47:2000;221-224
12. Wang X., Karlsson J.O., Zhu C., Bahr B.A., Hagberg H., Blomgren K. Caspase-3 activation after neonatal rat cerebral hypoxia-ischemia. Biol Neonate. 79:2001;172-179
13. Nakajima W., Ishida A., Lange M.S., Gabrielson K.L., Wilson M.A., Martin L.J., et al. Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat. J Neurosci. 20:2000;7994-8004
14. Ciccoli L., Rossi V., Leoncini S., Signorini C., Paffetti P., Bracci R., et al. Iron release in erythrocytes and plasma non protein-bound iron in hypoxic and non hypoxic newborns. Free Radic Res. 37:2003;51-58
15. Comporti M., Signorini C., Buonocore G., Ciccoli L. Iron release, oxidative stress and erythrocyte ageing. Free Radic Biol Med. 32:2002;568-576
16. Ozawa H., Nishida A., Mito T., Takashima S. Development of ferritin-positive cells in cerebrum of human brain. Pediatr Neurol. 10:1994;44-48
17. Heffner J.E., Repine J.E. Pulmonary strategies of antioxidant defense. Am Rev Respir Dis. 140:1989;531-554
18. Shadid M., Buonocore G., Groenendaal F., Moison R., Ferrali M., Berger H.M., et al. Effect of deferoxamine and allopurinol on non protein bound iron concentrations in plasma and cortical brain tissue of newborn lambs following hypoxia ischemia. Neurosci Lett. 248:1998;5-8
19. Buonocore G., Perrone S., Gioia D., Gatti M.G., Massafra C., Agosta R., et al. Nucleated red blood cell count at birth as an index of perinatal brain damage. Am J Obstet Gynecol. 181:1999;1500-1505
20. Buonocore G., Perrone S., Longini M., Paffetti P., Vezzosi P., Gatti M.G., et al. Non protein bound iron as early predictive marker of neonatal brain damage. Brain. 126:2003;1224-1230
21. Klebanoff S.J. Oxygen metabolism and the toxic properties of phagocytes. Ann Intern Med. 93:1980;480-489
22. Buonocore G., Gioia D., De Filippo M., Picciolini E., Bracci R. Superoxide anion release by polymorphonuclear leukocytes in whole blood of newborns and mothers during the peripartal period. Pediatr Res. 36:1994;619-622
23. Toti P., De Felice C., Palmeri M.L., Villanova M., Martin J.J., Buonocore G. Inflammatory pathogenesis of cortical polymicrogyria: an autopsy study. Pediatr Res. 44:1998;291-296
24. Elimian A., Verma U., Beneck D., Cipriano R., Visintainer P., Tejani N. Histologic chorioamnionitis, antenatal steroids, and perinatal outcomes. Obstet Gynecol. 96:2000;333-336
25. Bracci R., Buonocore G. Chorioamnionitis: a risk factor for fetal and neonatal morbidity. Biol Neonate. 83:2003;85-96
26. Dammann O., Leviton A. Maternal intrauterine infection, citokines, and brain damage in the preterm newborn. Pediatr Res. 42:1997;1-8
27. Yoon B.H., Romero R., Kim C.J., Koo J.N., Choe G., Syn H.C., et al. High expression of tumor necrosis factor-α and interleukin-6 in periventricular leukomalacia. Am J Obstet Gynecol. 177:1997;406-411
28. Gu Y., Sarnecki C., Aldape R.A., Livingston D.J., Su M.S. Cleavage of poly(ADP-ribose) polymerase by interleukin-1 beta converting enzyme and its homologs TX and Nedd-2. J Biol Chem. 270:1995;18715-18718
29. Gordon N. Apoptosis (programmed cell death) and other reasons for elimination of neurons and axons. Brain Dev. 17:1995;73-77
30. Columbano A. Cell death: current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo. J Cell Biochem. 58:1995;181-190
31. Mehmet H., Yue X., Squier M.V., Lorek A., Cady E., Penrice J., et al. Increased apoptosis in the cingulate sulcus of newborn piglets following transient hypoxia-ischaemia is related to the degree of high energy phosphate depletion during the insult. Neurosci Lett. 181:1994;121-125
32. Mishra O.P., Qayyum I., Delivoria-Papadopoulos M. Hypoxia-induced modification of the inositol triphosphate receptor in neuronal nuclei of newborn piglets: role of nitric oxide. J Neurosci Res. 74:2003;333-338
33. Szabo C. Role of nitric oxide in endotoxic shock: an overview of recent advances. Ann N Y Acad Sci. 851:1998;422-425
34. Beckman J.S., Crow J.P. Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem Soc Trans. 21:1993;330-334
35. 2+ is dependent on mitochondrial-generated reactive oxygen species. FEBS Lett. 378:1996;150-152
36. Kroemer G., Dallaporta B., Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol. 60:1998;619-642
37. Ashkenazi A., Dixit V.M. Death receptors: signaling and modulation. Science. 281:1998;1305-1308
38. Meini A., Benocci A., Frosini M., Sgaragli G.P., Garcia J.B., Pessina G.P., et al. Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage. Eur J Neurosci. 17:2003;692-700
39. Esplugues J.V. NO as a signalling molecule in the nervous system. Br J Pharmacol. 135:2002;1079-1095
40. Yun H.Y., Dawson V.L., Dawson T.M. Nitric oxide in health and disease of the nervous system. Mol Psychiatry. 2:1997;300-310
41. Berridge M.J., Bootman M.D., Lipp P. Calcium: a life and death signal. Nature. 395:1998;645-648
42. Mannick J.B., Hausladen A., Liu L., Hess D.T., Zeng M., Miao Q.X., et al. Fas-induced caspase denitrosylation. Science. 284:1999;651-654
43. Buonocore G., Liberatori S., Bini L., Mishra O.P., Delivoria-Papadopoulos M., Pallini V., et al. Hypoxic response of synaptosomal proteins in term guinea pig fetuses. J Neurochem. 73:1999;2139-2148
44. Tsujimoto Y. Bcl-2 family of proteins: life-or-death switch in mitochondria. Biosci Rep. 22:2002;47-58
45. Shimizu S., Narita M., Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature. 399:1999;483-487
46. Inder T., Mocatta T., Darlow B., Spencer C., Volpe J.J., Winterbourn C. Elevated free radical products in the cerebrospinal fluid of VLBW infants with cerebral white matter injury. Pediatr Res. 52:2002;213-218
47. Muttukrishna S., Fowler P.A., George L., Groome N.P., Knight P.G. Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy. J Clin Endocrinol Metab. 81:1996;3328-3334
48. Florio P., Benedetto C., Luisi S., Santuz M., Di Carlo C., Marozio L., et al. Activin A, inhibin A, inhibin B and parturition: changes of maternal serum and cord levels according to the mode of delivery. Br J Obstet Gynecol. 106:1999;1061-1065
49. Debieve F., Beerlandt S., Hubinont C., Thomas K. Gonadotropins, prolactin, inhibin A, inhibin B, and activin A in human fetal serum from midpregnancy and term pregnancy. J Clin Endocrinol Metab. 85:2000;270-274
50. Petraglia F., Florio P., Nappi C., Genazzani A.R. Peptide signaling in human placenta and membranes autocrine, paracrine, and endocrine mechanisms. Endocr Rev. 17:1996;156-181
51. Florio P., Cobellis L., Luisi S., Ciarmela P., Severi F.M., Bocchi C., et al. Changes in inhibins and activin secretion in healthy and pathological pregnancies. Mol Cell Endocrinol. 180:2001;123-130
52. Roberts J.M., Cooper D.W. Pathogenesis and genetics of pre-eclampsia. Lancet. 357:2001;53-56
53. Jenkin G., Ward J., Hooper S., O'Connor A., de Kretser D., Wallace E. Feto-placental hypoxemia regulates the release of fetal activin A and prostaglandin E(2). Endocrinology. 142:2001;963-966
54. Wu D.D., Lai M., Hughes P.E., Sirimanne E., Gluckman P.D., Williams C.E. Expression of the activin axis and neuronal rescue effects of recombinant activin A following hypoxic-ischemic brain injury in the infant rat. Brain Res. 835:1999;369-378
55. Lai M., Sirimanne E., Williams C.E., Gluckman P.D. Sequential patterns of inhibin subunit gene expression following hypoxic-ischemic injury in the rat brain. Neuroscience. 70:1996;1013-1024
56. Buonocore G., Perrone S., Longini M., Vezzosi P., Marzocchi B., Paffetti P., et al. Oxidative stress in preterm newborn at birth and on the seventh day of life. Pediatr Res. 52:2002;46-49
57. Petraglia F., Gomez R., Luisi S., Florio P., Tolosa J.E., Stomati M., et al. Increased midtrimester amniotic fluid activin A: a risk factor for subsequent fetal death. Am J Obstet Gynecol. 180:1999;194-197