Specific downregulation and mistargeting of the lipid raft-associated protein MAL in a glycolipid storage disorder

Neurobiology of Disease

Volumn 16, Issue 2, 2004, Pages 396-406

  Saravanan, K ^a   Schaeren Wiemers, N ^b   Klein, D ^a   Sandhoff, R ^c   Schwarz, A ^a   Yaghootfam, A ^a   Gieselmann, V ^a   Franken, S ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

2 ,3 cyclic nucleotide 3 phosphodiesterase; Arylsulfatase A; ASA; CNPase; DIGs; Glycosphingolipids; Intracellular transport; Lipid rafts; Lipid storage disease; Metachromatic leukodystrophy

Indexed keywords

CEREBROSIDE SULFATASE;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MODEL; DISEASE SEVERITY; EPITHELIUM CELL; KIDNEY EPITHELIUM; LIPID COMPOSITION; LYSOSOME MEMBRANE; METACHROMATIC LEUKODYSTROPHY; MOUSE; MYELIN SHEATH; NONHUMAN; OLIGODENDROGLIA; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TARGETING; RECEPTOR DOWN REGULATION; REDUCTION; REGULATORY MECHANISM;

ANIMALS; BIOLOGICAL TRANSPORT; CEREBROSIDE-SULFATASE; DETERGENTS; DOWN-REGULATION; KIDNEY; LEUKODYSTROPHY, METACHROMATIC; LYSOSOMES; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, MUTANT STRAINS; MYELIN PROTEINS; MYELIN SHEATH; PROTEOLIPIDS; SULFOGLYCOSPHINGOLIPIDS;

EID: 2942585129     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.03.008     Document Type: Article

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