Detergent-insoluble glycosphingolipid/cholesterol microdomains of the myelin membrane

Journal of Neurochemistry

Volumn 81, Issue 5, 2002, Pages 993-1004

  Taylor, Christopher M ^a   Coetzee, Timothy ^a,b   Pfeiffer, Steven E ^c  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b National Multiple Sclerosis Society   (United States)

^c NONE

Author keywords

Detergent extraction; Detergent insoluble glycosphingolipid cholesterol enriched microdomains (DIG); Raft

Indexed keywords

CHOLESTEROL; DETERGENT; GLYCOSPHINGOLIPID;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CHEMICAL ANALYSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR CLONING; MOUSE; MYELIN SHEATH; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN LIPID INTERACTION; PROTEIN PURIFICATION; SOLUBILIZATION;

ANIMALS; CENTRIFUGATION, DENSITY GRADIENT; CHEMICAL FRACTIONATION; CHOLESTEROL; CHOLIC ACIDS; DETERGENTS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GLYCOSPHINGOLIPIDS; MACROMOLECULAR SUBSTANCES; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; MYELIN SHEATH; PLANT OILS; POLYETHYLENE GLYCOLS; SOLUBILITY;

ANIMALIA;

EID: 0036319382     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00884.x     Document Type: Article

References (88)

1. Purification and partial structural and functional characterization of mouse myelin/oligodendrocyte glycoprotein
2. Association of GAP-43 with detergent-resistant membranes requires two palmitoylated cysteine residues
3. Developmental expression of 2′,3′-cyclic nucleotide 3′-phosphohydrolase in dissociated fetal rat brain cultures and rat brain
4. Reversible inhibition of oligodendrocyte progenitor differentiation by a monoclonal antibody against surface galactolipids
5. Inhibition of protein and lipid sulfation in oligodendrocytes blocks biological responses to FGF-2 and retards cytoarchitectural maturation, but not developmental lineage progression
6. Negative regulation of oligodendrocyte differentiation by galactosphingolipids
7. Identification of prelarge and presmall basic proteins in mouse myelin and their structural relationship to large and small basic proteins
8. Immunocytochemical localization by electron microscopy of 2′3′-cyclic nucleotide 3′-phosphodiesterase in developing oligodendrocytes of normal and mutant brain
9. 2′,3′-Cyclic nucleotide 3′-phosphodiesterase has characteristics of cytoskeletal proteins. A hypothesis for its function
10. Identification of GTP-binding proteins in myelin and oligodendrocyte membranes
11. Isolation and characterization of a novel oligodendrocyte-specific protein
12. Oligodendrocyte-specific protein (OSP) is a major component of CNS myelin
13. Functions of lipid rafts in biological membranes
14. Structure and origin of ordered lipid domains in biological membranes
15. Structure and function of sphingolipid- and cholesterol-rich membrane rafts
16. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface
17. Detergent insolubility of alkaline phosphatase during biosynthetic transport and endocytosis. Role of cholesterol
18. The phosphoinositide signaling cycle in myelin requires cooperative interaction with the axon
19. VIP17/MAL, a lipid raft-associated protein, is involved in apical transport in MDCK cells
20. The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases
21. Evaluation of prototype transmembrane 4 superfamily protein complexes and their relation to lipid rafts
22. Myelination in the absence of galactocerebroside and sulfatide: Normal structure with abnormal function and regional instability
23. Molecular cloning, chromosomal mapping, and characterization of the mouse UDP-galactose: Ceramide galactosyl-transferase gene
24. Isoprenylation of brain 2′,3′-cyclic nucleotide 3′-phosphodiesterase modulates cell morphology
25. 2′,3′-Cyclic nucleotide 3′-phosphodiesterase binds to actin-based cytoskeletal elements in an isoprenylation-independent manner
26. Binding of 2′,3′-cyclic nucleotide 3′-phosphodiesterase to myelin: An in vitro study
27. Myelin galactolipids are essential for proper node of Ranvier formation in the CNS
28. Myelin abnormalities in mice deficient in galactocerebroside and sulfatide
29. Axo-glial interactions regulate the localization of axonal paranodal proteins
30. Organization of oligodendroglial membrane sheets. I: Association of myelin basic protein and 2′,3′-cyclic nucleotide 3′-phosphohydrolase with cytoskeleton
31. Glycolipids and transmembrane signaling: Antibodies to galactocerebroside cause a calcium influx in oligodendrocytes
32. 2+ responses in oligodendrocytes
33. Glycosphingolipid-enriched, detergent-insoluble complexes in protein sorting in epithelial cells
34. Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains
35. rMAL is a glycosphingolipid-associated protein of myelin and apical membranes of epithelial cells in kidney and stomach
36. Microdomains of GPI-anchored proteins in living cells revealed by crosslinking
37. Myelin/oligodendrocyte glycoprotein is a unique member of the immunoglobulin superfamily
38. Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin
39. Expression of genes for the myelin-specific proteins in oligodendrocytes in vivo demands the presence of axons
40. Current concepts of PLP and its role in the nervous system
41. Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: Accumulation of actin regulated by local tyrosine phosphorylation
42. Lipid domain structure of the plasma membrane revealed by patching of membrane components
43. Phosphatidylinositol is involved in the membrane attachment of NCAM-120, the smallest component of the neural cell adhesion molecule
44. Solubilization of membranes by detergents
45. Properties of detergents
46. Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane
47. The structure and function of myelin oligodendrocyte glycoprotein
48. Cloning and characterization of MVP17: A developmentally regulated myelin protein in oligodendrocytes
49. Myelin glycosphingolipid/cholesterol-enriched microdomains selectively sequester the non-compact myelin proteins CNP and MOG
50. Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor
51. Oligodendrocytes direct glycosyl phosphatidylinositol-anchored proteins to the myelin sheath in glycosphingolipid-rich complexes
52. Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination
53. Axon-myelin transfer of phospholipids and phospholipid precursors. Labeling of myelin phosphoinositides through axonal transport
54. Neuronal polarity: Essential role of protein-lipid complexes in axonal sorting
55. Proteins of myelin
56. Use of cyclodextrins to monitor transbilayer movement and differential lipid affinities of cholesterol
57. A novel myelin associated glycoprotein defined by a mouse monoclonal antibody
58. Functionally different GPI proteins are organized in different domains on the neuronal surface
59. Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains
60. Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes
61. Glycosphingolipids are not essential for formation of detergent-resistant membrane rafts in melanoma cells. Methyl-beta-cyclodextrin does not affect cell surface transport of a GPI-anchored protein
62. The oligodendrocyte and its many cellular processes
63. Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover
64. Drug solubilizers to aid pharmacologists: Amorphous cyclodextrin derivatives
65. Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction
66. Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells
67. The MAL proteolipid is necessary for normal apical transport and accurate sorting of the influenza virus hemagglutinin in Madin-Darby canine kidney cells
68. Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane
69. Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate
70. Oligodendroglia regulate the regional expansion of axon caliber and local accumulation of neurofilaments during development independently of myelin formation
71. Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells
72. Functional rafts in cell membranes
73. Lipid rafts and signal transduction
74. Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains
75. GPI-anchored cell-surface molecules complexed to protein tyrosine kinases
76. Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol
77. Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site
78. Soluble myelin-associated glycoprotein (MAG) found in vivo inhibits axonal regeneration
79. Initial events of myelination involve Fyn tyrosine kinase signalling
80. Stimulation of myelin basic protein gene transcription by Fyn tyrosine kinase for myelination
81. GPI-anchored proteins are organized in submicron domains at the cell surface
82. T lymphocyte costimulation mediated by reorganization of membrane microdomains
83. Different sphingolipids show differential partitioning into sphingolipid/cholesterol-rich domains in lipid bilayers
84. Epidermal growth factor receptor activation is localized within low-buoyant density, non-caveolar membrane domains
85. Role for the oligodendrocyte cytoskeleton in myelination
86. Monoclonal antibodies against myelin proteolipid protein: Identification and characterization of two major determinants
87. Cellular cholesterol efflux mediated by cyclodextrins. Demonstration of kinetic pools and mechanism of efflux
88. Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons