Protease-activated receptor-2-mediated inhibition for Ca2+ response to lipopolysaccharide in guinea pig tracheal epithelial cells

American Journal of Respiratory Cell and Molecular Biology

Volumn 30, Issue 6, 2004, Pages 886-892

  Oshiro, Akihiro ^a   Otani, Hitomi ^a   Yagi, Yasuhiro ^a   Fukuhara, Shirou ^a   Inagaki, Chiyoko ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; BUFFER; BUTYLATE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CHELERYTHRINE; FURA 2; LIPOPOLYSACCHARIDE; OKADAIC ACID; PHORBOL 12,13 DIBUTYLATE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C INHIBITOR; PROTEINASE ACTIVATED RECEPTOR 2; QUINAPYRAMINE SULFATE; STAUROSPORINE; TRYPSIN; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CONTROLLED STUDY; GUINEA PIG; INCUBATION TIME; MOLECULAR INTERACTION; MUCOSA CELL; NONHUMAN; TRACHEA MUCOSA;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ANIMALS; CALCIUM; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNELS; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; GUINEA PIGS; ISOENZYMES; LIPOPOLYSACCHARIDES; OKADAIC ACID; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RECEPTOR, PAR-2; RESPIRATORY MUCOSA; TRACHEA; TRYPSIN;

ANIMALIA; BRONCHUS; CAVIA PORCELLUS; RICKETTSIA SP. PAR; SUS SCROFA;

EID: 2942580974     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2003-0223OC     Document Type: Article

References (32)

1. Polito, A. J., and D. Proud. 1998. Epithelial cells as regulators of airway inflammation. J. Allergy Clin. Immunol. 102:714-718.
2. Sun, G., M. A. Stacey, M. Schmidt, L. Mori, and S. Mattoli. 2001. Interaction of mite allergens Der P3 and Der P9 with protease-activated receptor-2 expressed by lung epithelial cells. J. Immunol. 167:1014-1021.
3. Rochelle, L. G., B. M. Fischer, and K. B. Adler. 1998. Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro. Free Radic. Biol. Med. 24:863-868.
4. 2+ mobilization. Am. J. Respir. Cell Mol. Biol. 19:293-299.
5. Vliagoftis, H., A. D. Befus, M. D. Hollenberg, and R. Moqbel. 2001. Airway epithelial cells release eosinophil survival-promoting factors (GM-CSF) after stimulation of proteinase-activated receptor 2. J. Allergy Clin. Immunol. 107:679-685.
6. Cocks, T. M., and J. D. Moffatt. 2000. Protease-activated receptors: sentries for inflammation? Trends Pharmacol. Sci. 21:103-108.
7. Macfarlane, S. R., M. J. Seatter, T. Kanke, G. D. Hunter, and R. Plevin. 2001. Proteinase-activated receptors. Pharmacol. Rev. 53:245-282.
8. Cocks, T. M., B. Fong, J. M. Chow, G. P. Anderson, A. G. Frauman, R. G. Goldie, P. J. Henry, M. J. Carr, J. R. Hamilton, and J. D. Moffatt. 1999. A protective role for protease-activated receptors in the airways. Nature 398:156-160.
9. 2+ signalling in guinea pig tracheal epithelial cells. Life Sci. 71:547-558.
10. Mule, F., M. C. Baffi, M. Falzone, and M. C. Cerra. 2002. Signal transduction pathways involved in the mechanical responses to protease-activated receptors in rat colon. J. Pharmacol. Exp. Ther. 303:1265-1272.
11. 2 release from human respiratory epithelial cells. J. Immunol. 168:3577-3585.
12. Vliagoftis, H., A. Schwingshackl, C. D. Milne, M. Duszyk, M. D. Hollenberg, J. L. Wallace, A. D. Befus, and R. Moqbel. 2000. Protease-activated receptor-2-mediated matrix metalloproteinase-9 release from airway epithelial cells. J. Allergy Clin. Immunol. 106:537-545.
13. Knight, D. A., S. Lim, A. K. Scaffidi, N. Roche, K. F. Chung, G. A. Stewart, and P. J. Thompson. 2001. Protease-activated receptors in human airway: Upregulation of PAR-2 in respiratory epithelium from patients with athma. J. Allergy Clin. Immunol. 108:797-803.
14. Wang, Z., P. Malmberg, A. EK, K. Larsson, and L. Palmberg. 1999. Swine dust induces cytokine secretion from human epithelial cells and alveolar macrophages. Clin. Exp. Immunol. 115:6-12.
15. Stamme, C., M. Muller, L. Hamann, T. Gutsmann, and U. Seydel. 2002. Surfactant protein A inhibits lipopolysaccharide-induced immune cell activation by preventing the interaction of lipopolysaccharide with lipopolysaccharide- binding protein. Am. J. Respir. Cell Mol. Biol. 27:353-360.
16. Vernooy, J. H. J., M. A. Dentener, R. J. van Suylen, W. A. Buurman, and E. F. M. Wouters. 2001. Intratracheal instillation of lipopolysaccharide in mice induces apoptosis in bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 24:569-576.
17. Moffatt, J. D., K. L. Jeffrey, and T. M. Cocks. 2002. Protease-activated receptor-2 activating peptide SLIGRL inhibits bacterial lipopolysaccharide- induced recruitment of polymorphonuclear leukocytes into the airways of mice. Am. J. Respir. Cell Mol. Biol. 26:680-684.
18. Enomoto, N., S. Yamashita, M. Goto, P. Schemmer, and R. G. Thurman. 1999. Desensitization to LPS after ethanol involves the effect of endotoxin on voltage-dependent calcium channels. Am. J. Physiol. 277:G1251-G1258.
19. Wu, R., and D. Smith. 1982. Continuous multiplication of rabbit tracheal epithelial cells in a defined, hormone-supplemented medium. In Vitro 18:800-812.
20. 2- adrenoceptor-mediated regulation of synoviocyte populations. Jpn. J. Pharmacol. 85:214-226.
21. Gomez, J.-P., N. Fares, and D. Potreau. 1996. Effects of Bay K 8644 on L-type calcium current from newborn rat cardiomyocytes in primary culture. J. Mol. Cell. Cardiol. 28:2217-2229.
22. Davare, M., M. C. Horne, and J. W. Hell. 2000. Protein phosphatase 2A is associated with class C L-type calcium channels (Caν1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase. J. Biol. Chem. 275:39710-39717.
23. Wheeler, M. D., and R. G. Thurman. 1999. Production of superoxide and TNF-α from alveolar macrophages is blunted by glycine. Am. J. Physiol. 277:L952-L959.
24. Smith, R. P., R. Shellard, G. Di Benedetto, C. J. Magnus, and A. Mehta. 1996. Interaction between calcium, neutral endopeptidase and the substance P mediated ciliary response in human respiratory epithelium. Eur. Respir. J. 9:86-92.
25. 2+ channels (Caν1.2a,b) by protein kinases. Am. J. Physiol. 281:C1743-C1756.
26. Kamp, T. J., and J. W. Hell. 2000. Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ. Res. 87:1095-1102.
27. McHugh, D., E. M. Sharp, T. Scheuer, and W. A. Catterall. 2000. Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain. Proc. Natl. Acad. Sci. USA 97:12334-12338.
28. Puri, T. S., B. L. Gerhardstein, X.-L. Zhao, M. B. Ladner, and M. M. Hosey. 1997. Differential effects of subunit interactions on protein kinase A- and C-mediated phosphorylation of L-type calcium channels. Biochemistry 36:9605-9615.
29. Kawabata, A., R. Kuroda, N. Morimoto, N. Kawao, T. Masuko, K. Kakehi, K. Kataoka, M. Taneda, H. Nishikawa, and H. Araki. 2001. Lipopolysaccharide-induced subsensitivity of protease-activated receptor-2 in the mouse salivary glands in vivo. Naunyn-Schmiedeberg's Arch. Pharmacol. 364:281-284.
30. Cicala, C., A. Pinto, M. Bucci, R. Sorrentino, B. Walker, P. Harriot, A. Cruchley, S. Kapas, G. L. Howells, and G. Cirino. 1999. Protease-activated receptor-2 involvement in hypertension in normal and endotoxemic rats in vivo. Circulation 99:2590-2597.
31. Reibman, J., A. T. Talbot, Y. Hsu, G. Ou, J. Jover, D. Nilsen, and M. H. Pillinger. 2000. Regulation of expression of granulocyte-macrophage colony-stimulating factor in human bronchial epithelial cells: roles of protein kinase C and mitogen-activated protein kinases. J. Immunol. 165:1618-1625.
32. Cross, T. G., D. Scheel-Toellner, N. V. Henriquez, E. Deacon, M. Salmon, and J. M. Load. 2000. Serine/threonine protein kinases and apoptosis. Exp. Cell Res. 256:34-41.