Intratracheal instillation of lipopolysaccharide in mice induces apoptosis in bronchial epithelial cells: No role for tumor necrosis factor-α and infiltrating neutrophils

American Journal of Respiratory Cell and Molecular Biology

Volumn 24, Issue 5, 2001, Pages 569-576

  Vernooy, Juanita H J ^a,b   Dentener, Mieke A ^a,b   Van Suylen, Robert Jan ^a,b   Buurman, Wim A ^a,b   Wouters, Emiel F M ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CIGARETTE SMOKE CONDENSATE; CONCENTRATION (PARAMETERS); DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DNA NUCLEOTIDYLEXOTRANSFERASE; EPITHELIUM CELL; GENE KNOCKOUT; LIPOPOLYSACCHARIDE; LUNG ALVEOLUS CELL; NEUTROPHIL; POLYMERASE CHAIN REACTION; STAINING; TUMOR NECROSIS FACTOR ALPHA;

ANIMALIA;

EID: 0035030992     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.24.5.4156     Document Type: Article

References (37)

1. 1. Bohlinger, I., M. Leist, F. Gantner, S. Angermuller, G. Tiegs, and A. Wendel. 1996. DNA fragmentation in mouse organs during endotoxic shock. Am. J. Pathol. 149:1381-1393.
2. 2. Haimovitz Friedman, A., C. Cordon Cardo, S. Bayoumy, M. Garzotto, M. McLoughlin, R. Gallily, C. K. Edwards, III, E. H. Schuchman, Z. Fuks, and R, Kolesnick. 1997. Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J. Exp. Med. 186:1831-1841.
3. 3. Fujita, M., K. Kuwano, R. Kunitake, N. Hagimoto, H. Miyazaki, Y. Kaneko, M. Kawasaki, T. Maeyama, and N. Hara. 1998. Endothelial cell apoptosis in lipopolysaccharide-induced lung injury in mice. Int. Arch. Allergy Immunol. 117:202-208.
4. 4. Kline, J. N., J. D. Cowden, G. W. Hunninghake, B. C. Schutte, J. L. Watt, C. L. Wohlford Lenane, L. S. Powers, M. P. Jones, and D. A. Schwartz. 1999. Variable airway responsiveness to inhaled lipopolysaccharide. Am. J. Respir. Crit. Care Med. 160:297-303.
5. 5. Rylander, R., P. Haglind, and M. Lundholm. 1985. Endotoxin in cotton dust and respiratory function decrement among cotton workers in an experimental cardroom. Am. Rev. Respir. Dis. 131:209-213.
6. 6. Hasday, J. D., R. Bascom, J. J. Costa, T. Fitzgerald, and W. Dubin. 1999. Bacterial endotoxin is an active component of cigarette smoke. Chest 115: 829-835.
7. 7. Wagner, J. G., and R. A. Roth. 1999. Neutrophil migration during endotoxemia. J. Leukoc. Biol. 66:10-24.
8. 8. McDonald, R. J., and J. Usachencko. 1999. Neutrophils injure bronchial epithelium after ozone exposure. Inflammation 23:63-73.
9. 9. Bingisser, R., C. Stey, M. Weller, P. Groscurth, E. Russi, and K. Frei. 1996. Apoptosis in human alveolar macrophages is induced by endotoxin and is modulated by cytokines. Am. J. Respir. Cell Mol. Biol. 15:64-70.
10. 10. Hoyt, D. G., R. J. Mannix, J. M. Rusnak, B. R. Pitt, and J. S. Lazo. 1995. Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells. Am. J. Physiol. 269:L171-L177.
11. 11. Frey, E. A., and B. B. Finlay. 1998. Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14 dependent pathway. Microb. Pathog. 24:101-109.
12. 12. Eugster, H. P., M. Muller, U. Karrer, B. D. Car, B. Schnyder, V. M. Eng, G. Woerly, M. Le Hir, F. di Padova, M. Aguet, R. Zinkernagel, H. Bluethmann, and B. Ryffel. 1996. Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice. Int. Immunol. 8:23-36.
13. 13. Starcher, B., and I. Williams. 1989. A method for intratracheal instillation of endotoxin into the lungs of mice. Lab. Anim. 23:234-240.
14. 14. Walley, K. R., T. E. McDonald, Y. Higashimoto, and S. Hayashi. 1999. Modulation of proinflammatory cytokines by nitric oxide in murine acute lung injury. Am. J. Respir. Crit. Care Med. 160:698-704.
15. 15. Shellito, J. E., J. K. Kolls, and W. R. Summer. 1995. Regulation of nitric oxide release by macrophages after intratracheal lipopolysaccharide. Am. J. Respir. Cell Mol. Biol. 13:45-53.
16. 16. Bemelmans, M. H., D. J. Gouma, J. W. Greve, and W. A. Buurman. 1993. Effect of antitumour necrosis factor treatment on circulating tumour necrosis factor levels and mortality after surgery in jaundiced mice. Br. J. Surg. 80:1055-1058.
17. 17. Dentener, M. A., F. T. Smit, G. J. Francot, and W. A. Buurman. 1994. Characterization of two monoclonal antibodies directed against bactericidal/ permeability-increasing protein. J. Infect. Dis. 170:1483-1489.
18. 18. Gavrieli, Y., Y. Sherman, and S. A. Ben Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
19. 19. Kuebler, W. M., C. Abels, L. Schuerer, and A. E. Goetz. 1996. Measurement of neutrophil content in brain and lung tissue by a modified myeloperoxidase assay. Int. J. Microcirc. Clin. Exp. 16:89-97.
20. 20. Daemen, M. A., M. W. van de Ven, E. Heineman, and W. A. Buurman. 1999. Involvement of endogenous interleukin-10 and tumor necrosis factor-alpha in renal ischemia-reperfusion injury. Transplantation 67:792-800.
21. 21. Dentener, M. A., J. W. Greve, J. G. Maessen, and W. A. Buurman. 1989. Role of tumour necrosis factor in the enhanced sensitivity of mice to endotoxin after exposure to lead. Immunopharmacol. Immunotoxicol. 11:321-334.
22. 22. Ishii, Y., K. Hashimoto, A. Nomura, T. Sakamoto, Y. Uchida, M. Ohtsuka, S. Hasegawa, and M. Sagai. 1998. Elimination of neutrophils by apoptosis during the resolution of acute pulmonary inflammation in rats. Lung 176:89-98.
23. 23. Cox, G., J. Crossley, and Z. Xing. 1995. Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am. J. Respir. Cell Mol. Biol. 12:232-237.
24. 24. Urbaschek, B., and R. Urbaschek. 1979. The inflammatory response to endotoxins. Bibl. Anal. 17:74-104.
25. 25. Berczi, I., L. Bertok, and T. Bereznai. 1966. Comparative studies on the toxicity of Escherichia coli lipopolysaccharide endotoxin in various animal species. Can. J. Microbiol. 12:1070-1071.
26. 26. Rask Andersen, A., P. Malmberg, and M. Lundholm. 1989. Endotoxin levels in farming: absence of symptoms despite high exposure levels. Br. J. Ind. Med. 46:412-416.
27. 27. Staley, K., A. J. Blaschke, and J. Chun. 1997. Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends. Cell Death Diff. 4:66-75.
28. 28. Aoshiba, K., S. I. Rennard, and J. R. Spurzem. 1997. Cell-matrix and cell-cell interactions modulate apoptosis of bronchial epithelial cells. Am. J. Physiol. 272:L28-L37.
29. 29. Arreto, C.-D., C. Dumarey, M.-A. Nahori, and B. B. Vargaftig. 1997. The LPS-induced neutrophil recruitment into rat air pouches is mediated by TNF: likely macrophage origin. Med. Inflam. 6:335-343.
30. 30. Johnston, C. J., J. N. Finkelstein, R. Gelein, and G. Oberdorster. 1998. Pulmonary cytokine and chemokine mRNA levels after inhalation of lipopolysaccharide in C57BL/6 mice. Toxicol. Sci. 46:300-307.
31. 31. Mallampalli, R. K., E. J. Peterson, A. B. Carter, R. G. Salome, S. N. Mathur, and G. A. Koretzky. 1999. TNF-alpha increases ceramide without inducing apoptosis in alveolar type II epithelial cells. Am. J. Physiol. 276: L481-L490.
32. 32. Pushkareva, M., L. M. Obeid, and Y. A. Hannun. 1995. Ceramide: an endogenous regulator of apoptosis and growth suppression. Immunol. Today 16:294-297.
33. 33. Hirschfeld, M., Y. Ma, J. H. Weis, S. N. Vogel, and J. J. Weis. 2000. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J. Immunol. 165:618-622.
34. 34. Matsumura, T., A. Ito, T. Takii, H. Hayashi, and K. Onozaki. 2000. Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes. J. Interferon Cytokine Res. 20:915-921.
35. 35. Joseph, C. K., S. D. Wright, W. G. Bornmann, J. T. Randolph, E. R. Kumar, R. Bittman, J. Liu, and R. N. Kolesnick. 1994. Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells. J. Biol. Chem. 269:17606-17610.
36. 36. Wurfel, M. M., and S. D. Wright. 1997. Lipopolysaccharide-binding protein and soluble CD14 transfer lipopolysaccharide to phospholipid bilayers: preferential interaction with particular classes of lipid. J. Immunol. 158: 3925-3934.
37. 37. Williams, G. T. 1994. Programmed cell death: a fundamental protective response to pathogens. Trends Microbiol. 2:463-464.