-
1
-
-
0032763709
-
Impaired transport of leptin across the blood-brain barrier in obesity
-
Banks WA, DiPalma CR & Farrell CL 1999 Impaired transport of leptin across the blood-brain barrier in obesity. Peptides 20 1341-1345.
-
(1999)
Peptides
, vol.20
, pp. 1341-1345
-
-
Banks, W.A.1
DiPalma, C.R.2
Farrell, C.L.3
-
2
-
-
0037456304
-
STAT3 signalling is required for leptin regulation oF energy balance but not reproduction
-
Bates SH, Stearns WH, Dundon TA, Schubert M, Tso AW, Wang Y, Banks AS, Lavery HJ, Haq AK, Maratos-Flier E et al. 2003 STAT3 signalling is required for leptin regulation oF energy balance but not reproduction. Nature 421 856-859.
-
(2003)
Nature
, vol.421
, pp. 856-859
-
-
Bates, S.H.1
Stearns, W.H.2
Dundon, T.A.3
Schubert, M.4
Tso, A.W.5
Wang, Y.6
Banks, A.S.7
Lavery, H.J.8
Haq, A.K.9
Maratos-Flier, E.10
-
3
-
-
0033775615
-
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
-
Bustin SA 2000 Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. Journal of Molecular Endocrinology 25 169-193.
-
(2000)
Journal of Molecular Endocrinology
, vol.25
, pp. 169-193
-
-
Bustin, S.A.1
-
4
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P & Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 162 156-159.
-
(1987)
Analytical Biochemistry
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
5
-
-
0033931981
-
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
-
El-Haschimi K, Pierroz DD, Hileman SM, Bjorbaek C & Flier JS 2000 Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. Journal of Clinical Investigation 105 1827-1832.
-
(2000)
Journal of Clinical Investigation
, vol.105
, pp. 1827-1832
-
-
El-Haschimi, K.1
Pierroz, D.D.2
Hileman, S.M.3
Bjorbaek, C.4
Flier, J.S.5
-
6
-
-
0036020281
-
Long-term food restriction prevents ageing-associated central leptin resistance in Wistar rats
-
Fernandez-Galaz C, Fernandez-Agullo T, Perez C, Peralta S, Arribas C, Andres A, Carrascosa JM & Ros M 2002 Long-term food restriction prevents ageing-associated central leptin resistance in Wistar rats. Diabetologia 45 997-1003.
-
(2002)
Diabetologia
, vol.45
, pp. 997-1003
-
-
Fernandez-Galaz, C.1
Fernandez-Agullo, T.2
Perez, C.3
Peralta, S.4
Arribas, C.5
Andres, A.6
Carrascosa, J.M.7
Ros, M.8
-
7
-
-
0033615425
-
Obesity research. Leptin not impressive in clinical trial
-
Gura T 1999 Obesity research. Leptin not impressive in clinical trial. Science 286 881-882.
-
(1999)
Science
, vol.286
, pp. 881-882
-
-
Gura, T.1
-
8
-
-
0030737953
-
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
-
Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton DA & Friedman JM 1997 Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. PNAS 94 8878-8883.
-
(1997)
PNAS
, vol.94
, pp. 8878-8883
-
-
Halaas, J.L.1
Boozer, C.2
Blair-West, J.3
Fidahusein, N.4
Denton, D.A.5
Friedman, J.M.6
-
9
-
-
0035895826
-
Enhanced inhibitory feeding response to alpha-melanocyte stimulating hormone in the diet-induced obese rat
-
Hansen MJ, Ball MJ & Morris MJ 2001 Enhanced inhibitory feeding response to alpha-melanocyte stimulating hormone in the diet-induced obese rat. Brain Research 892 130-137.
-
(2001)
Brain Research
, vol.892
, pp. 130-137
-
-
Hansen, M.J.1
Ball, M.J.2
Morris, M.J.3
-
10
-
-
0034457883
-
In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: Overlapping but distinct pathways from insulin
-
Kim YB, Uotani S, Pierroz DD, Flier JS & Kahn BB 2000 In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin. Endocrinology 141 2328-2339.
-
(2000)
Endocrinology
, vol.141
, pp. 2328-2339
-
-
Kim, Y.B.1
Uotani, S.2
Pierroz, D.D.3
Flier, J.S.4
Kahn, B.B.5
-
14
-
-
0034284520
-
Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain
-
Lin S, Storlien LH & Huang XF 2000 Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain. Brain Research 875 89-95.
-
(2000)
Brain Research
, vol.875
, pp. 89-95
-
-
Lin, S.1
Storlien, L.H.2
Huang, X.F.3
-
15
-
-
0034268123
-
Differential expression of leptin receptor in high- and low-fat-fed Osborne-Mendel and S5B/Pl rats
-
Madiehe AM, Schaffhauser AO, Braymer DH, Bray GA & York DA 2000 Differential expression of leptin receptor in high- and low-fat-fed Osborne-Mendel and S5B/Pl rats. Obesity Research 8 467-474.
-
(2000)
Obesity Research
, vol.8
, pp. 467-474
-
-
Madiehe, A.M.1
Schaffhauser, A.O.2
Braymer, D.H.3
Bray, G.A.4
York, D.A.5
-
16
-
-
0033756298
-
Leptin resistance is associated with hypothalamic leptin receptor mRNA and protein downregulation
-
Martin RE, Perez E, He YJ, Dawson R Jr & Millard WJ 2000 Leptin resistance is associated with hypothalamic leptin receptor mRNA and protein downregulation. Metabolism 49 1479-1484.
-
(2000)
Metabolism
, vol.49
, pp. 1479-1484
-
-
Martin, R.E.1
Perez, E.2
He, Y.J.3
Dawson Jr., R.4
Millard, W.J.5
-
17
-
-
18444411313
-
Clinical implications of leptin and its potential humoral regulators in long-term low-calorie diet therapy for obese humans
-
Miyawaki T, Masuzaki H, Ogawa Y, Hosoda K, Nishimura H, Azuma N, Sugawara A, Masuda I, Murata M, Matsuo T et al. 2002 Clinical implications of leptin and its potential humoral regulators in long-term low-calorie diet therapy for obese humans. European Journal of Clinical Nutrition 56 593-600.
-
(2002)
European Journal of Clinical Nutrition
, vol.56
, pp. 593-600
-
-
Miyawaki, T.1
Masuzaki, H.2
Ogawa, Y.3
Hosoda, K.4
Nishimura, H.5
Azuma, N.6
Sugawara, A.7
Masuda, I.8
Murata, M.9
Matsuo, T.10
-
18
-
-
0037315042
-
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia
-
Niswender KD, Morrison CD, Clegg DJ, Olson R, Baskin DG, Myers MG Jr, Seeley RJ & Schwartz MW 2003 Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes 52 227-231.
-
(2003)
Diabetes
, vol.52
, pp. 227-231
-
-
Niswender, K.D.1
Morrison, C.D.2
Clegg, D.J.3
Olson, R.4
Baskin, D.G.5
Myers Jr., M.G.6
Seeley, R.J.7
Schwartz, M.W.8
-
20
-
-
0035851878
-
Peripheral and hypothalamic leptin resistance with age-related obesity
-
Scarpace PJ & Tumer N 2001 Peripheral and hypothalamic leptin resistance with age-related obesity. Physiology and Behavior 74 721-727.
-
(2001)
Physiology and Behavior
, vol.74
, pp. 721-727
-
-
Scarpace, P.J.1
Tumer, N.2
-
21
-
-
0034085453
-
Impaired leptin signal transduction with age-related obesity
-
Scarpace PJ, Matheny M & Slack EW 2000 Impaired leptin signal transduction with age-related obesity. Neuropharmacology 39 1872-1879.
-
(2000)
Neuropharmacology
, vol.39
, pp. 1872-1879
-
-
Scarpace, P.J.1
Matheny, M.2
Slack, E.W.3
-
22
-
-
0035800015
-
Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats
-
Scarpace PJ, Matheny M & Tumer N 2001 Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats. Neuroscience 104 1111-1117.
-
(2001)
Neuroscience
, vol.104
, pp. 1111-1117
-
-
Scarpace, P.J.1
Matheny, M.2
Tumer, N.3
-
23
-
-
0036226005
-
Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats
-
Scarpace PJ, Matheny M, Zhang Y, Tumer N, Frase CD, Shek EW, Hong B, Prima V & Zolotukhin S 2002 Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats. Neuropharmacology 42 548-561.
-
(2002)
Neuropharmacology
, vol.42
, pp. 548-561
-
-
Scarpace, P.J.1
Matheny, M.2
Zhang, Y.3
Tumer, N.4
Frase, C.D.5
Shek, E.W.6
Hong, B.7
Prima, V.8
Zolotukhin, S.9
-
24
-
-
0038168650
-
Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MTII
-
Scarpace PJ, Matheny M, Zolotukhin S, Tumer N & Zhang Y 2003 Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MTII. Neuropharmacology 45 211-219.
-
(2003)
Neuropharmacology
, vol.45
, pp. 211-219
-
-
Scarpace, P.J.1
Matheny, M.2
Zolotukhin, S.3
Tumer, N.4
Zhang, Y.5
-
25
-
-
0034714037
-
Resistance to the anorexic and thermogenic effects of centrally administrated leptin in obese aged rats
-
Shek EW & Scarpace PJ 2000 Resistance to the anorexic and thermogenic effects of centrally administrated leptin in obese aged rats. Regulatory Peptides 92 65-71.
-
(2000)
Regulatory Peptides
, vol.92
, pp. 65-71
-
-
Shek, E.W.1
Scarpace, P.J.2
-
27
-
-
0036000280
-
Leptin signalling
-
Sweeney G 2002 Leptin signalling. Cellular Signalling 14 655-663.
-
(2002)
Cellular Signalling
, vol.14
, pp. 655-663
-
-
Sweeney, G.1
-
28
-
-
0030807358
-
Diet-induced obese mice develop peripheral, but not central, resistance to leptin
-
Van Heck M, Compton DS, France CF, Tedesco RP, Fawzi AB, Graziano M P, Sybertz EJ, Strader CD & Davis HR Jr 1997 Diet-induced obese mice develop peripheral, but not central, resistance to leptin. Journal of Clinical Investigation 99 385-390.
-
(1997)
Journal of Clinical Investigation
, vol.99
, pp. 385-390
-
-
Van Heck, M.1
Compton, D.S.2
France, C.F.3
Tedesco, R.P.4
Fawzi, A.B.5
Graziano, M.P.6
Sybertz, E.J.7
Strader, C.D.8
Davis Jr., H.R.9
-
29
-
-
0036831235
-
Hypothalamic delivery of doxycycline-inducible leptin gene allows for reversible transgene expression and physiological responses
-
Wilsey J, Zolotukhin S, Prima V, Shek EW, Matheny MK & Scarpace PJ 2002 Hypothalamic delivery of doxycycline-inducible leptin gene allows for reversible transgene expression and physiological responses. Gene Therapy 9 1492-1499.
-
(2002)
Gene Therapy
, vol.9
, pp. 1492-1499
-
-
Wilsey, J.1
Zolotukhin, S.2
Prima, V.3
Shek, E.W.4
Matheny, M.K.5
Scarpace, P.J.6
-
30
-
-
0142063578
-
Central leptin gene therapy fails to overcome leptin resistance associated with diet-induced obesity
-
Wilsey J, Zolotukhin S, Prima V & Scarpace PJ 2003 Central leptin gene therapy fails to overcome leptin resistance associated with diet-induced obesity. American Journal of Physiology. Regulatory, Integrative, and Comparative Physiology 285 R1011-R1020.
-
(2003)
American Journal of Physiology. Regulatory, Integrative, and Comparative Physiology
, vol.285
-
-
Wilsey, J.1
Zolotukhin, S.2
Prima, V.3
Scarpace, P.J.4
-
31
-
-
0036321620
-
A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding
-
Zhao AZ, Huan JN, Gupta S, Pal R & Sahu A 2002 A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding. Nature Neuroscience 5 727-728.
-
(2002)
Nature Neuroscience
, vol.5
, pp. 727-728
-
-
Zhao, A.Z.1
Huan, J.N.2
Gupta, S.3
Pal, R.4
Sahu, A.5
|