Voltage sensor mutations differentially target misfolded K+ channel subunits to proteasomal and non-proteasomal disposal pathways

FEBS Letters

Volumn 568, Issue 1-3, 2004, Pages 110-116

  Myers, Michael P ^a,b   Khanna, Rajesh ^a,c   Lee, Eun Jeon ^a   Papazian, Diane M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

^c TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Biogenesis; Degradation; dMJ, deoxymannojirimycin; dNJ, deoxynojirimycin; ER, endoplasmic reticulum; ERAD, ER associated degradation; HEK293T, human embryonic kidney 293T cells; PBS, phosphate buffered saline; Quality control; Shaker channel

Indexed keywords

LACTACYSTIN; POTASSIUM CHANNEL; PROTEIN; PROTEIN D316K; PROTEIN K374E; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; BIOGENESIS; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; WILD TYPE;

CELL LINE; CYSTEINE ENDOPEPTIDASES; HUMANS; MICROSCOPY, FLUORESCENCE; MULTIENZYME COMPLEXES; MUTATION; POTASSIUM CHANNELS; PRECIPITIN TESTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING;

EID: 2942525752     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.05.023     Document Type: Article

References (49)

1. Hille B. Ionic Channels of Excitable Membranes. fourth ed. 2003;Sinauer Associates, Sunderland, MA
2. MacKinnon R. Nature. 350:1991;232-235
3. Schulteis C.T., Nagaya N., Papazian D.M. Biochemistry. 35:1996;12133-12140
4. Sokolova O., Kolmakova-Partensky L., Grigorieff N. Structure. 9:2001;215-220
5. Bezanilla F. Physiol. Rev. 80:2000;555-592
6. Papazian D.M., Silverman W.R., Lin M.A., Tiwari-Woodruff S.K., Tang C.Y. Novartis Found. Symp. 245:2002;178-190
7. Seoh S.A., Sigg D., Papazian D.M., Bezanilla F. Neuron. 16:1996;1159-1167
8. Aggarwal S.K., MacKinnon R. Neuron. 16:1996;1169-1177
9. Doyle D.A., Morais-Cabral J., Pfuetzner R.A., Kuo A., Gulbis J.M., Cohen S.L., Chait B.T., MacKinnon R. Science. 280:1998;69-77
10. Morais-Cabral J.H., Zhou Y., MacKinnon R. Nature. 414:2001;37-42
11. Zhou Y., Morais-Cabral J.H., Kaufman A., MacKinnon R. Nature. 414:2001;43-48
12. Deutsch C. Annu. Rev. Physiol. 64:2002;19-46
13. Papazian D.M., Shao X.M., Seoh S.A., Mock A.F., Huang Y., Wainstock D.H. Neuron. 14:1995;1293-1301
14. Tiwari-Woodruff S.K., Schulteis C.T., Mock A.F., Papazian D.M. Biophys. J. 72:1997;1489-1500
15. Jiang Y., Lee A., Chen J., Ruta V., Cadene M., Chait B.T., MacKinnon R. Nature. 423:2003;33-41
16. Schulteis C.T., Nagaya N., Papazian D.M. J. Biol. Chem. 273:1998;26210-26217
17. Keller S.H., Lindstrom J., Taylor P. J. Biol. Chem. 273:1998;17064-17072
18. de Virgilio M., Kitzmuller C., Schwaiger E., Klein M., Kreibich G., Ivessa N.E. Mol. Biol. Cell. 10:1999;4059-4073
19. Chung D.H., Ohashi K., Watanabe M., Miyasaka N., Hirosawa S. J. Biol. Chem. 275:2000;4981-4987
20. Chillaron J., Adan C., Haas I.G. Biol. Chem. 381:2000;1155-1164
21. Wang J., White A.L. Biochemistry. 39:2000;8993-9000
22. Wilson C.M., Farmery M.R., Bulleid N.J. J. Biol. Chem. 275:2000;21224-21232
23. Jakob C.A., Chevet E., Thomas D.Y., Bergeron J.J. Results Probl. Cell Differ. 33:2001;1-17
24. Fagioli C., Sitia R. J. Biol. Chem. 276:2001;12885-12892
25. Tokunaga F., Hara K., Koide T. Arch. Biochem. Biophys. 411:2003;235-242
26. Kagan A., Yu Z., Fishman G.I., McDonald T.V. J. Biol. Chem. 275:2000;11241-11248
27. Schulteis C.T., John S.A., Huang Y., Tang C.Y., Papazian D.M. Biochemistry. 34:1995;1725-1733
28. Schwarz T.L., Papazian D.M., Caretto R.C., Jan Y.N., Jan L.Y. Neuron. 4:1990;119-127
29. Fenteany G., Schreiber S.L. J. Biol. Chem. 273:1998;8545-8548
30. Khanna R., Myers M.P., Lainé M., Papazian D.M. J. Biol. Chem. 276:2001;34028-34034
31. Nagaya N., Schulteis C.T., Papazian D.M. Receptors Channels. 6:1999;229-239
32. Nagaya N., Papazian D.M. J. Biol. Chem. 272:1997;3022-3027
33. Papazian D.M. Neuron. 23:1999;7-10
34. Ellgaard L., Helenius A. Nat. Rev. Mol. Cell. Biol. 4:2003;181-191
35. Jakob C.A., Burda P., Roth J., Aebi M. J. Cell Biol. 142:1998;1223-1233
36. Khanna, R., Lee, E.J. and Papazian, D.M. (2004) J. Cell Sci., in press
37. Cabral C.M., Choudhury P., Liu Y., Sifers R.N. J. Biol. Chem. 275:2000;25015-25022
38. Fayadat L., Siffroi-Fernandez S., Lanet J., Franc J.L. J. Biol. Chem. 275:2000;15948-15954
39. Gelman M.S., Kannegaard E.S., Kopito R.R. J. Biol. Chem. 277:2002;11709-11714
40. Jensen T.J., Loo M.A., Pind S., Williams D.B., Goldberg A.L., Riordan J.R. Cell. 83:1995;129-135
41. Loayza D., Michaelis S. Mol. Cell. Biol. 18:1998;779-789
42. Umebayashi K., Fukuda R., Hirata A., Horiuchi H., Nakano A., Ohta A., Takagi M. J. Biol. Chem. 276:2001;41444-41454
43. Geier E., Pfeifer G., Wilm M., Lucchiari-Hartz M., Baumeister W., Eichmann K., Niedermann G. Science. 283:1999;978-981
44. Wang E.W., Kessler B.M., Borodovsky A., Cravatt B.F., Bogyo M., Ploegh H.L., Glas R. Proc. Natl. Acad. Sci. USA. 97:2000;9990-9995
45. Johnston J.A., Ward C.L., Kopito R.R. J. Cell Biol. 143:1998;1883-1898
46. Popot J.L., Engelman D.M. Annu. Rev. Biochem. 69:2000;881-922
47. Popot J.L., Engelman D.M. Biochemistry. 29:1990;4031-4037
48. Tu L., Wang J., Helm A., Skach W.R., Deutsch C. Biochemistry. 39:2000;824-836
49. Sato Y., Sakaguchi M., Goshima S., Nakamura T., Uozumi N. Proc. Natl. Acad. Sci. USA. 99:2002;60-65