Importin α/β-mediated nuclear protein import is regulated in a cell cycle-dependent manner

Experimental Cell Research

Volumn 297, Issue 1, 2004, Pages 285-293

  Yasuhara, Noriko ^a   Takeda, Eri ^a   Inoue, Hitomi ^a   Kotera, Ippei ^a   Yoneda, Yoshihiro ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Cell cycle; Importin ; Importin ; Nuclear localization signal; Nuclear protein import

Indexed keywords

KARYOPHERIN ALPHA; KARYOPHERIN BETA;

ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE PHASE; CITRIC ACID CYCLE; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HUMAN CELL; KINETICS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 2942515033     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.03.010     Document Type: Article

References (31)

1. Mattaj I.W., Englmeier L. Nucleocytoplasmic transport: the soluble phase. Annu. Rev. Biochem. 67:1998;265-306
2. Görlich D., Kutay U. Transport between the cell nucleus and the cytoplasm. Annu. Rev. Cell Dev. Biol. 15:1999;607-660
3. Dingwall C., Laskey R.A. Nuclear targeting sequences - A consensus? Trends Biochem. Sci. 16:1991;478-481
4. Chi N.C., Adam E.J., Adam S.A. Sequence and characterization of cytoplasmic nuclear protein import factor p97. J. Cell Biol. 130:1995;265-274
5. Görlich D., Mattaj I.W. Nucleocytoplasmic transport. Science. 271:1996;1513-1518
6. Kalderon D., Roberts B.L., Richardson W.D., Smith A.E. A short amino acid sequence able to specify nuclear location. Cell. 39:1984;499-509
7. Lanford R.E., Butel J.S. Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen. Cell. 37:1984;801-813
8. Imamoto N., Shimamoto T., Kose S., Takao T., Tachibana T., Matsubae M., Sekimoto T., Shimonishi Y., Yoneda Y. The nuclear pore-targeting complex binds to nuclear pores after association with a karyophile. FEBS Lett. 368:1995;415-419
9. Imamoto N., Shimamoto T., Takao T., Tachibana T., Kose S., Matsubae M., Sekimoto T., Shimonishi Y., Yoneda Y. In vivo evidence for involvement of a 58 kDa component of nuclear pore-targeting complex in nuclear protein import. EMBO J. 14:1995;3617-3626
10. Moore M.S., Blobel G. The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature. 365:1993;661-663
11. Pollard V.W., Michael W.M., Nakielny S., Siomi M.C., Wang F., Dreyfuss G. A novel receptor-mediated nuclear protein import pathway. Cell. 86:1996;985-994
12. Moore J.D., Yang J., Truant R., Kornbluth S. Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1. J. Cell Biol. 144:1999;213-224
13. Nagoshi E., Imamoto N., Sato R., Yoneda Y. Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin β with HLH-Zip. Mol. Biol. Cell. 10:1999;2221-2233
14. Miyamoto Y., Hieda M., Harreman M.T., Fukumoto M., Saiwaki T., Hodel A.E., Corbett A.H., Yoneda Y. Importin α can migrate into the nucleus in an importin β- and Ran-independent manner. EMBO J. 21:2002;5833-5842
15. Hood J.K., Silver P.A. Diverse nuclear transport pathways regulate cell proliferation and oncogenesis. Biochim. Biophys. Acta. 1471:2000;M31-M41
16. Bootsma D., Budke L., Vos O. Studies on synchronous division of tissue culture cells initiated by excess thymidine. Exp. Cell Res. 33:1964;301-309
17. Yoneda Y., Imamoto-Sonobe N., Yamaizumi M., Uchida T. Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells. Exp. Cell Res. 173:1987;586-595
18. Faleiro L., Lazebnik Y. Caspases disrupt the nuclear-cytoplasmic barrier. J. Cell Biol. 151:2000;951-959
19. Yoshihiro Y. Nucleocytoplasmic protein traffic and its significance to cell function. Genes Cells. 5:2000;777-787
20. Köhler M., Speck C., Christiansen M., Bischoff F.R., Prehn S., Haller H., Görlich D., Hartmann E. Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import. Mol. Cell Biol. 11:1999;7782-7791
21. Sekimoto T., Imamoto N., Nakajima K., Hirano T., Yoneda Y. Extracellular signal-dependent nuclear import of stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, not Rch1. EMBO J. 16:1997;7067-7077
22. McBride K.M., Banninger G., McDonald C., Reich N.C. Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-α EMBO J. 21:2002;1754-1763
23. Feldherr C.M., Akin D. The permeability of the nuclear envelope in dividing and nondividing cell cultures. J. Cell Biol. 111:1990;1-8
24. Tachibana T., Hieda M., Yoneda Y. Up-regulation of nuclear protein import by nuclear localization signal sequences in living cells. FEBS Lett. 442:1999;235-240
25. Winey M., Yarar D., Giddings T.H. Jr., Mastronarde D.N. Nuclear pore complex number and distribution throughout the Saccharomyces cerevisiae cell cycle by three-dimensional reconstruction from electron micrographs of nuclear envelopes. Mol. Biol. Cell. 8:1997;2119-2132
26. Yamaguchi R., Newport J. A Role for Ran-GTP and Crm1 in blocking re-replication. Cell. 113:2003;115-125
27. Weis K. Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle. Cell. 112:2003;441-451
28. Walther T.C., Askjaer P., Gentzel M., Habermann A., Griffiths G., Wilm M., Mattaj I.W., Hetzer M. RanGTP mediates nuclear pore complex assembly. Nature. 424:2003;689-694
29. Künzler M., Hurt E. Targeting of Ran: variation on a common theme? J. Cell Sci. 114:2001;3233-3241
30. Kehlenbach R.H., Gerace L. Phosphorylation of the nuclear transport machinery down-regulates nuclear protein import in vitro. J. Biol. Chem. 275:2000;17848-17856
31. Lindsay M.E., Plafker K., Smith A.E., Clurman B.E., Macara I.G. Npap60/Nup50 is a tri-stable switch that stimulates importin-α/β- mediated nuclear protein import. Cell. 110:2002;349-360