Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity

European Journal of Neuroscience

Volumn 22, Issue 12, 2005, Pages 2985-2994

  Iki, Junko ^a,e   Inoue, Akihiro ^a   Bito, Haruhiko ^c,d   Okabe, Shigeo ^a,b,d,e  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

BDNF; Cytoskeleton; Mouse; NMDA receptor; Postsynaptic density

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; F ACTIN; GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN SH3; PROTEIN TYROSINE KINASE INHIBITOR;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DENDRITIC SPINE; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS REGULATION; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; RECEPTOR SOLUBILIZATION; SIGNAL TRANSDUCTION;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; ANTIBODIES; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CARRIER PROTEINS; CELLS, CULTURED; CORTACTIN; DEPSIPEPTIDES; DRUG INTERACTIONS; EMBRYO; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; MUTAGENESIS; MUTATION; N-METHYLASPARTATE; NEURONS; PHOSPHOPROTEIN PHOSPHATASE; PYRIMIDINES; RECEPTOR, TRKB; RECEPTORS, N-METHYL-D-ASPARTATE; SRC HOMOLOGY DOMAINS; SYNAPSES; TIME FACTORS; TRANSFECTION; VESICULAR GLUTAMATE TRANSPORT PROTEIN 1;

EID: 29344475419     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2005.04510.x     Document Type: Article

References (40)

1. Allison, D.W., Gelfand, V.I., Spector, I. & Craig, A.M. (1998) Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors. J. Neurosci., 18, 2423-2436.
2. Bibel, M. & Barde, Y. A. (2000) Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev., 14, 2919-2937.
3. Boeckers, T.M., Kreutz, M.R., Winter, C., Zuschratter, W., Smalla, K.H., Sanmarti-Vila, L., Wex, H., Langnaese, K., Bockmann, J., Garner, C.C. & Gundelfinger, E.D. (1999) Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density. J. Neurosci., 19, 6506-6518.
4. Campbell, D.H., Sutherland, R.L. & Daly, R.J. (1999) Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin. Cancer Res., 59, 5376-5385.
5. Du Weed, S.A.Y. & Parsons, J.T. (1998) Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1. J. Cell Sci., 111, 2433-2443.
6. Ebihara, T., Kawabata, I., Usui, S., Sobue, K. & Okabe, S. (2003) Synchronized formation and remodeling of postsynaptic densities: long-term visualization of hippocampal neurons expressing postsynaptic density proteins tagged with green fluorescent protein. J. Neurosci., 23, 2170-2181.
7. 2+ channels. Proc. Natl Acad. Sci. USA, 99, 14458-14463.
8. Halpain, S., Hipolito, A. & Saffer, L. (1998) Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin. J. Neurosci., 18, 9835-9844.
9. Hering, H. & Sheng, M. (2003) Activity-dependent redistribution and essential role of cortactin in dendritic spine morphogenesis. J. Neurosci., 23, 11759-11769.
10. Horch, H.W. & Katz, L.C. (2002) BDNF release from single cells elicits local dendritic growth in nearby neurons. Nat. Neurosci., 5, 1177-1184.
11. Huang, C., Liu, J., Haudenschild, C.C. & Zhan, X. (1998) The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells. J. Biol. Chem., 273, 25770-25776.
12. Itami, C., Kimura, F., Kohno, T., Matsuoka, M., Ichikawa, M., Tsumoto, T. & Nakamura, S. (2003) BDNF-dependent unmasking of "silent" synapses in the developing mouse barrel cortex. Proc. Natl. Acad. Sci. USA, 100, 13069-13074.
13. Iwasato, T., Datwani, A., Wolf, A.M., Nishiyama, H., Taguchi, Y., Tonegawa, S., Knopfel, T., Erzurumlu, R.S. & Itohara, S. (2000) Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex. Nature, 406, 726-731.
14. Kohara, K., Kitamura, A., Adachi, N., Nishida, M., Itami, C., Nakamura, S. & Tsumoto, T. (2003) Inhibitory but not excitatory cortical neurons require presynaptic brain-derived neurotrophic factor for dendritic development, as revealed by chimera Cell culture. J. Neurosci., 23, 6123-6131.
15. Kohara, K., Kitamura, A., Morishima, M. & Tsumoto, T. (2001) Activity-dependent transfer of brain-derived neurotrophic factor to postsynaptic neurons. Science, 291, 2419-2423.
16. Li, Y., Erzurumlu, R.S., Chen, C., Jhaveri, S. & Tonegawa, S. (1994) Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell, 76, 427-437.
17. Manabe, T. (2002) Does BDNF have pre- or postsynaptic targets? Science, 295, 1651-1653.
18. Martinez, M.C., Ochiishi, T., Majewski, M. & Kosik, K.S. (2003) Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho. J. Cell Biol., 162, 99-111.
19. Martinez-Quiles, N., Ho, H.Y., Kirschner, M.W., Ramesh, N. & Geha, R.S. (2004) Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP. Mol. Cell Biol., 24, 5269-5280.
20. McAllister, A.K., Lo, D.C. & Katz, L.C. (1995) Neurotrophins regulate dendritic growth in developing visual cortex. Neuron, 15, 791-803.
21. McNiven, M.A., Kim, L., Krueger, E.W., Orth, J.D., Cao, H. & Wong, T.W. (2000) Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape. J. Cell Biol., 151, 187-198.
22. Naisbitt, S., Kim, E., Tu, J.C., Xiao, B., Sala, C., Valtschanoff, J., Weinberg, R.J., Worley, P.F. & Sheng, M. (1999) Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin. Neuron, 23, 569-582.
23. Nakanishi, S. (1992) Molecular diversity of glutamate receptors and implications for brain function. Science, 258, 597-603.
24. Nobes, C.D., Hawkins, P., Stephens, L. & Hall, A. (1995) Activation of the small GTP-binding proteins rho and rac by growth factor receptors. J. Cell Sci., 108, 225-233.
25. Okabe, S., Kim, H.D., Miwa, A., Kuriu, T. & Okado, H. (1999) Continual remodeling of postsynaptic density and its regulation by synaptic activity. Nat. Neurosci., 2, 804-811.
26. Okabe, S., Miwa, A. & Okado, H. (2001) Spine formation and correlated assembly of presynaptic and postsynaptic molecules. J. Neurosci., 21, 6105-6114.
27. Okamoto, K., Nagai, T., Miyawaki, A. & Hayashi, Y. (2004) Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nat. Neurosci., 7, 1104-1112.
28. Racz, B. & Weinberg, R.J. (2004) The subcellular organization of cortactin in hippocampus. J. Neurosci., 24, 10310-10317.
29. Rutherford, L.C., DeWan, A., Lauer, H.M. & Turrigiano, G.G. (1997) Brain-derived neurotrophic factor mediates the activity-dependent regulation of inhibition in neocortical cultures. J. Neurosci., 17, 4527-4535.
30. Sala, C., Piech, V., Wilson, N.R., Passafaro, M., Liu, G. & Sheng, M. (2001) Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron, 31, 115-130.
31. Selbach, M., Moese, S., Hurwitz, R., Hauck, C.R., Meyer, T.F. & Backert, S. (2003) The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation. EMBO J., 22, 515-528.
32. Shen, K. & Meyer, T. (1999) Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation. Science, 284, 162-166.
33. Star, E.N., Kwiatkowski, D.J. & Murthy, V.N. (2002) Rapid turnover of actin in dendritic spines and its regulation by activity. Nat. Neurosci., 5, 239-246.
34. Thoenen, H. (1995) Neurotrophins and neuronal plasticity. Science, 270, 593-598.
35. Usui, S., Konno, D., Hori, K., Maruoka, H., Okabe, S., Fujikado, T., Tano, Y. & Sobue, K. (2003) Synaptic targeting of PSD-Zip45 (Homer 1c) and its involvement in the synaptic accumulation of F-actin. J. Biol. Chem., 278, 10619-10628.
36. Watanabe, M., Fukaya, M., Sakimura, K., Manabe, T., Mishina, M. & Inoue, Y. (1998) Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre-recipient layer) of the mouse hippocampal CA3 subfield. Eur. J. Neurosci., 10, 478-487.
37. Wu, H. & Parsons, J.T. (1993) Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex. J. Cell Biol., 120, 1417-1426.
38. Wu, H., Reynolds, A.B., Kanner, S.B., Vines, R.R. & Parsons, J.T. (1991) Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol. Cell Biol., 11, 5113-5124.
39. Wyszynski, M., Lin, J., Rao, A., Nigh, E., Beggs, A.H., Craig, A.M. & Sheng, M. (1997) Competitive binding of alpha-actinin and calmodulin to the NMDA receptor. Nature, 385, 439-442.
40. Zafra, F., Hengerer, B., Leibrock, J., Thoenen, H. & Lindholm, D. (1990) Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J., 9, 3545-3550.