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Volumn 171, Issue 1-2, 2006, Pages 156-162

In vitro Th2 deviation of myelin-specific peripheral blood lymphocytes from patients with multiple sclerosis

Author keywords

Enzyme linked immunospot (ELISPOT); Immune deviation; Interferon ; Interleukin 4; Multiple sclerosis; Myelin; Peripheral blood mononuclear cells (PBMC)

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 15; INTERLEUKIN 4; MYELIN;

EID: 29244473858     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2005.09.013     Document Type: Article
Times cited : (3)

References (41)
  • 1
    • 0026710184 scopus 로고
    • IL-4 plays a dominant role in the differential development of Tho into Th1 and Th2 cells
    • O. Abehsira-Amar, M. Gibert, M. Joliy, J. Theze, and D.L. Jankovic IL-4 plays a dominant role in the differential development of Tho into Th1 and Th2 cells J. Immunol. 148 1992 3820 3829
    • (1992) J. Immunol. , vol.148 , pp. 3820-3829
    • Abehsira-Amar, O.1    Gibert, M.2    Joliy, M.3    Theze, J.4    Jankovic, D.L.5
  • 2
    • 0031791122 scopus 로고    scopus 로고
    • In vitro differentiation of peripheral blood T cells towards a type 2 phenotype is impaired in rheumatoid arthritis (RA)
    • S. Asselin, H. Conjeaud, D. Fradelizi, and M. Breban In vitro differentiation of peripheral blood T cells towards a type 2 phenotype is impaired in rheumatoid arthritis (RA) Clin. Exp. Immunol. 114 1998 284 292
    • (1998) Clin. Exp. Immunol. , vol.114 , pp. 284-292
    • Asselin, S.1    Conjeaud, H.2    Fradelizi, D.3    Breban, M.4
  • 4
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
    • A. Boyum Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g Scand. J. Clin. Lab. Invest., Suppl. 97 1968 77 89
    • (1968) Scand. J. Clin. Lab. Invest., Suppl. , vol.97 , pp. 77-89
    • Boyum, A.1
  • 5
    • 0025029064 scopus 로고
    • Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells
    • T.L. Chang, C.M. Shea, S. Urioste, R.C. Thompson, W.H. Boom, and A.K. Abbas Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells J. Immunol. 145 1990 2803 2808
    • (1990) J. Immunol. , vol.145 , pp. 2803-2808
    • Chang, T.L.1    Shea, C.M.2    Urioste, S.3    Thompson, R.C.4    Boom, W.H.5    Abbas, A.K.6
  • 6
    • 0021213218 scopus 로고
    • Reverse enzyme-linked immunospot assay (RELISPOT) for the detection of cells secreting immunoreactive substances
    • C.C. Czerkinsky, A. Tarkowski, L.A. Nilsson, O. Ouchterlony, H. Nygren, and C. Gretzer Reverse enzyme-linked immunospot assay (RELISPOT) for the detection of cells secreting immunoreactive substances J. Immunol. Methods 72 1984 489 496
    • (1984) J. Immunol. Methods , vol.72 , pp. 489-496
    • Czerkinsky, C.C.1    Tarkowski, A.2    Nilsson, L.A.3    Ouchterlony, O.4    Nygren, H.5    Gretzer, C.6
  • 7
    • 0030965918 scopus 로고    scopus 로고
    • Th1-like responses to peptides from peripheral nerve myelin proteins in patients with polyneuropathy associated with monoclonal gammopathy
    • C. Ekerfelt, J. Ernerudh, and M. Vrethem Th1-like responses to peptides from peripheral nerve myelin proteins in patients with polyneuropathy associated with monoclonal gammopathy Clin. Exp. Immunol. 108 1997 516 522
    • (1997) Clin. Exp. Immunol. , vol.108 , pp. 516-522
    • Ekerfelt, C.1    Ernerudh, J.2    Vrethem, M.3
  • 8
    • 0035142517 scopus 로고    scopus 로고
    • Transfer of myelin-specific cells deviated in vitro towards IL-4 production ameliorates ongoing experimental allergic neuritis
    • C. Ekerfelt, C. Dahle, R. Weissert, M. Kvarnstrom, T. Olsson, and J. Ernerudh Transfer of myelin-specific cells deviated in vitro towards IL-4 production ameliorates ongoing experimental allergic neuritis Clin. Exp. Immunol. 123 2001 112 118
    • (2001) Clin. Exp. Immunol. , vol.123 , pp. 112-118
    • Ekerfelt, C.1    Dahle, C.2    Weissert, R.3    Kvarnstrom, M.4    Olsson, T.5    Ernerudh, J.6
  • 9
    • 0035991759 scopus 로고    scopus 로고
    • The use of cell products for treatment of autoimmune neuroinflammatory diseases
    • J. Ernerudh, G. Berlin, and C. Ekerfelt The use of cell products for treatment of autoimmune neuroinflammatory diseases Curr. Med. Chem. 9 2002 1497 1505
    • (2002) Curr. Med. Chem. , vol.9 , pp. 1497-1505
    • Ernerudh, J.1    Berlin, G.2    Ekerfelt, C.3
  • 10
    • 0034517626 scopus 로고    scopus 로고
    • Interferon-gamma and interleukin-4-producing T cells in peripheral blood of multiple sclerosis patients
    • D. Franciotta, E. Zardini, R. Bergamaschi, L. Andreoni, and V. Cosi Interferon-gamma and interleukin-4-producing T cells in peripheral blood of multiple sclerosis patients Eur. Cytokine Netw. 11 2000 677 681
    • (2000) Eur. Cytokine Netw. , vol.11 , pp. 677-681
    • Franciotta, D.1    Zardini, E.2    Bergamaschi, R.3    Andreoni, L.4    Cosi, V.5
  • 11
    • 0029984051 scopus 로고    scopus 로고
    • Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10
    • F. Gerosa, C. Paganin, D. Peritt, F. Paiola, M.T. Scupoli, M. Aste-Amezaga, I. Frank, and G. Trinchieri Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10 J. Exp. Med. 183 1996 2559 2569
    • (1996) J. Exp. Med. , vol.183 , pp. 2559-2569
    • Gerosa, F.1    Paganin, C.2    Peritt, D.3    Paiola, F.4    Scupoli, M.T.5    Aste-Amezaga, M.6    Frank, I.7    Trinchieri, G.8
  • 12
    • 0036546066 scopus 로고    scopus 로고
    • New concepts in the immunopathogenesis of multiple sclerosis
    • B. Hemmer, J.J. Archelos, and H.P. Hartung New concepts in the immunopathogenesis of multiple sclerosis Nat. Rev. Neurosci. 3 2002 291 301
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 291-301
    • Hemmer, B.1    Archelos, J.J.2    Hartung, H.P.3
  • 13
    • 0031984320 scopus 로고    scopus 로고
    • Augmentation of naive, Th1 and Th2 effector CD4 responses by IL-6, IL-1 and TNF
    • S.B. Joseph, K.T. Miner, and M. Croft Augmentation of naive, Th1 and Th2 effector CD4 responses by IL-6, IL-1 and TNF Eur. J. Immunol. 28 1998 277 289
    • (1998) Eur. J. Immunol. , vol.28 , pp. 277-289
    • Joseph, S.B.1    Miner, K.T.2    Croft, M.3
  • 14
    • 0029047940 scopus 로고
    • Polarized type 2 alloreactive CD4+ and CD8+ donor T cells fail to induce experimental acute graft-versus-host disease
    • W. Krenger, K.M. Snyder, J.C. Byon, G. Falzarano, and J.L. Ferrara Polarized type 2 alloreactive CD4+ and CD8+ donor T cells fail to induce experimental acute graft-versus-host disease J. Immunol. 155 1995 585 593
    • (1995) J. Immunol. , vol.155 , pp. 585-593
    • Krenger, W.1    Snyder, K.M.2    Byon, J.C.3    Falzarano, G.4    Ferrara, J.L.5
  • 17
    • 0028962552 scopus 로고
    • Induction of a Th2 population from a polarized Leishmania-specific Th1 population by in vitro culture with IL-4
    • S. Mocci, and R.L. Coffman Induction of a Th2 population from a polarized Leishmania-specific Th1 population by in vitro culture with IL-4 J. Immunol. 154 1995 3779 3787
    • (1995) J. Immunol. , vol.154 , pp. 3779-3787
    • Mocci, S.1    Coffman, R.L.2
  • 18
    • 0037460115 scopus 로고    scopus 로고
    • Lymphocyte traffic control by chemokines: Follicular B helper T cells
    • B. Moser, and L. Ebert Lymphocyte traffic control by chemokines: follicular B helper T cells Immunol. Lett. 85 2003 105 112
    • (2003) Immunol. Lett. , vol.85 , pp. 105-112
    • Moser, B.1    Ebert, L.2
  • 19
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • T.R. Mosmann, and R.L. Coffman TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties Annu. Rev. Immunol. 7 1989 145 173
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 20
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • T.R. Mosmann, and S. Sad The expanding universe of T-cell subsets: Th1, Th2 and more Immunol. Today 17 1996 138 146
    • (1996) Immunol. Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 21
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • T.R. Mosmann, H. Cherwinski, M.W. Bond, M.A. Giedlin, and R.L. Coffman Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins J. Immunol. 136 1986 2348 2357
    • (1986) J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 23
    • 0036177482 scopus 로고    scopus 로고
    • IL-15 induces type 1 and type 2 CD4+ and CD8+ T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12/IL-4 stimulation in vitro
    • W. Niedbala, X. Wei, and F.Y. Liew IL-15 induces type 1 and type 2 CD4+ and CD8+ T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12/IL-4 stimulation in vitro Eur. J. Immunol. 32 2002 341 347
    • (2002) Eur. J. Immunol. , vol.32 , pp. 341-347
    • Niedbala, W.1    Wei, X.2    Liew, F.Y.3
  • 24
    • 0034090602 scopus 로고    scopus 로고
    • Anti-inflammatory cytokines
    • S.M. Opal, and V.A. DePalo Anti-inflammatory cytokines Chest 117 2000 1162 1172
    • (2000) Chest , vol.117 , pp. 1162-1172
    • Opal, S.M.1    Depalo, V.A.2
  • 25
    • 0031569531 scopus 로고    scopus 로고
    • Crossregulation between T helper cell (Th)1 and Th2: Inhibition of Th2 proliferation by IFN-gamma involves interference with IL-1
    • T.B. Oriss, S.A. McCarthy, B.F. Morel, M.A. Campana, and P.A. Morel Crossregulation between T helper cell (Th)1 and Th2: inhibition of Th2 proliferation by IFN-gamma involves interference with IL-1 J. Immunol. 158 1997 3666 3672
    • (1997) J. Immunol. , vol.158 , pp. 3666-3672
    • Oriss, T.B.1    McCarthy, S.A.2    Morel, B.F.3    Campana, M.A.4    Morel, P.A.5
  • 27
    • 0029083269 scopus 로고
    • Interleukin-10 gene knock-out mice: A model of chronic inflammation
    • D. Rennick, N. Davidson, and D. Berg Interleukin-10 gene knock-out mice: a model of chronic inflammation Clin. Immunol. Immunopathol. 76 1995 S174 S178
    • (1995) Clin. Immunol. Immunopathol. , vol.76
    • Rennick, D.1    Davidson, N.2    Berg, D.3
  • 28
    • 0343773445 scopus 로고    scopus 로고
    • IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease
    • M. Rocken, M. Racke, and E.M. Shevach IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease Immunol. Today 17 1996 225 231
    • (1996) Immunol. Today , vol.17 , pp. 225-231
    • Rocken, M.1    Racke, M.2    Shevach, E.M.3
  • 29
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, and M. Toda Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases J. Immunol. 155 1995 1151 1164
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 31
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • F. Sallusto, D. Lenig, R. Forster, M. Lipp, and A. Lanzavecchia Two subsets of memory T lymphocytes with distinct homing potentials and effector functions Nature 401 1999 708 712
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 32
    • 0032414448 scopus 로고    scopus 로고
    • Effect of IL-4, IFN-gamma and IL-12 on cytokine production from human CD45RA and CD45RO CD4 T cell precursors
    • J. Sasama, B. Vyas, M. Vukmanovic-Stejic, and D.M. Kemeny Effect of IL-4, IFN-gamma and IL-12 on cytokine production from human CD45RA and CD45RO CD4 T cell precursors Int. Arch. Allergy Immunol. 117 1998 255 262
    • (1998) Int. Arch. Allergy Immunol. , vol.117 , pp. 255-262
    • Sasama, J.1    Vyas, B.2    Vukmanovic-Stejic, M.3    Kemeny, D.M.4
  • 33
    • 0041381363 scopus 로고    scopus 로고
    • Similarities and differences in CD4+ and CD8+ effector and memory T cell generation
    • R.A. Seder, and R. Ahmed Similarities and differences in CD4+ and CD8+ effector and memory T cell generation Nat. Immunol. 4 2003 835 842
    • (2003) Nat. Immunol. , vol.4 , pp. 835-842
    • Seder, R.A.1    Ahmed, R.2
  • 35
    • 0027132107 scopus 로고
    • IL4 dictates T-cell differentiation
    • S.L. Swain IL4 dictates T-cell differentiation Res. Immunol. 144 1993 616 620
    • (1993) Res. Immunol. , vol.144 , pp. 616-620
    • Swain, S.L.1
  • 36
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • S.L. Swain, A.D. Weinberg, M. English, and G. Huston IL-4 directs the development of Th2-like helper effectors J. Immunol. 145 1990 3796 3806
    • (1990) J. Immunol. , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 38
    • 0035886928 scopus 로고    scopus 로고
    • In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells
    • X. Wang, and T. Mosmann In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells J. Exp. Med. 194 2001 1069 1080
    • (2001) J. Exp. Med. , vol.194 , pp. 1069-1080
    • Wang, X.1    Mosmann, T.2
  • 39
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+ CD25+ regulatory T cells in patients with multiple sclerosis
    • V. Viglietta, C. Baecher-Allan, H.L. Weiner, and D.A. Hafler Loss of functional suppression by CD4+ CD25+ regulatory T cells in patients with multiple sclerosis J. Exp. Med. 199 2004 971 979
    • (2004) J. Exp. Med. , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 40
    • 1542329574 scopus 로고    scopus 로고
    • IL-4-mediated inhibition of IFN-gamma production by CD4+ T cells proceeds by several developmentally regulated mechanisms
    • O. Wurtz, M. Bajenoff, and S. Guerder IL-4-mediated inhibition of IFN-gamma production by CD4+ T cells proceeds by several developmentally regulated mechanisms Int. Immunol. 16 2004 501 508
    • (2004) Int. Immunol. , vol.16 , pp. 501-508
    • Wurtz, O.1    Bajenoff, M.2    Guerder, S.3
  • 41
    • 0033215144 scopus 로고    scopus 로고
    • Antigen-specific T cells in autoimmune diseases with a focus on multiple sclerosis and experimental allergic encephalomyelitis
    • B.G. Xiao, and H. Link Antigen-specific T cells in autoimmune diseases with a focus on multiple sclerosis and experimental allergic encephalomyelitis Cell. Mol. Life Sci. 56 1999 5 21
    • (1999) Cell. Mol. Life Sci. , vol.56 , pp. 5-21
    • Xiao, B.G.1    Link, H.2


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