메뉴 건너뛰기




Volumn 340, Issue 1, 2006, Pages 268-276

Transcriptional silencing of EphB6 receptor tyrosine kinase in invasive breast carcinoma cells and detection of methylated promoter by methylation specific PCR

Author keywords

5 Aza 2 deoxycytidine; Breast cancer; Breast carcinoma cell lines; EphB6; Methylation specific PCR; Sodium bisulfite sequencing; Transcriptional silencing

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; EPHRIN RECEPTOR B6; PROTEIN P300; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR SP1;

EID: 29244470819     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.11.174     Document Type: Article
Times cited : (40)

References (47)
  • 3
    • 0141594935 scopus 로고    scopus 로고
    • From developmental disorder to heritable cancer, its all in the BMP/TGF-beta family
    • K.A. Waite, and C. Eng From developmental disorder to heritable cancer, its all in the BMP/TGF-beta family Nat. Rev. Genet. 10 2003 763 773
    • (2003) Nat. Rev. Genet. , vol.10 , pp. 763-773
    • Waite, K.A.1    Eng, C.2
  • 4
    • 0242456170 scopus 로고    scopus 로고
    • Axis of evil: Molecular mechanisms of cancer metastasis
    • T. Bogenrieder, and M. Herlyn Axis of evil: molecular mechanisms of cancer metastasis Oncogene 22 2003 6524 6536
    • (2003) Oncogene , vol.22 , pp. 6524-6536
    • Bogenrieder, T.1    Herlyn, M.2
  • 5
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc protein
    • S. Adhikary, and M. Eilers Transcriptional regulation and transformation by Myc protein Nat. Rev. Mol. Cell Biol. 8 2005 635 645
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 6
    • 0038364114 scopus 로고    scopus 로고
    • Transcriptional repression in eukaryotes: Repressors and repression mechanisms
    • K. Gaston, and P.S. Jajaraman Transcriptional repression in eukaryotes: repressors and repression mechanisms Cell. Mol. Life Sci. 60 2003 721 741
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 721-741
    • Gaston, K.1    Jajaraman, P.S.2
  • 7
    • 0026479395 scopus 로고
    • The basic RNA polymerase II transcriptional machinery
    • R. Weinmann The basic RNA polymerase II transcriptional machinery Gene Expr. 2 1992 81 91
    • (1992) Gene Expr. , vol.2 , pp. 81-91
    • Weinmann, R.1
  • 8
    • 21244481727 scopus 로고    scopus 로고
    • The theoretical basis of transcriptional therapy of cancer: Can it be put into practice?
    • A.M. Melnick, K. Adelson, and J.D. Licht The theoretical basis of transcriptional therapy of cancer: can it be put into practice? J. Clin. Oncol. 17 2005 3957 3970
    • (2005) J. Clin. Oncol. , vol.17 , pp. 3957-3970
    • Melnick, A.M.1    Adelson, K.2    Licht, J.D.3
  • 9
    • 3242657117 scopus 로고    scopus 로고
    • The clinical application of targeting cancer through histone acetylation and hypomethylation
    • J. Gilbert, S.D. Gore, J.G. Herman, and M.A. Carducci The clinical application of targeting cancer through histone acetylation and hypomethylation Clin. Cancer Res. 14 2004 4589 4596
    • (2004) Clin. Cancer Res. , vol.14 , pp. 4589-4596
    • Gilbert, J.1    Gore, S.D.2    Herman, J.G.3    Carducci, M.A.4
  • 10
    • 16544395591 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • P.M. Das, and R. Singal DNA methylation and cancer J. Clin. Oncol. 22 2004 4632 4642
    • (2004) J. Clin. Oncol. , vol.22 , pp. 4632-4642
    • Das, P.M.1    Singal, R.2
  • 11
    • 20444369726 scopus 로고    scopus 로고
    • Development of pharmacogenomic markers to select preoperative chemotherapy for breast cancer
    • L. Pusztai, F.W. Symmans, and G.N. Hortobagyi Development of pharmacogenomic markers to select preoperative chemotherapy for breast cancer Breast Cancer 2 2005 73 85
    • (2005) Breast Cancer , vol.2 , pp. 73-85
    • Pusztai, L.1    Symmans, F.W.2    Hortobagyi, G.N.3
  • 13
    • 0033988651 scopus 로고    scopus 로고
    • Molecules in focus. Eph receptors and ephrins
    • N. Nakamoto Molecules in focus. Eph receptors and ephrins Int. J. Biochem. Cell Biol. 32 2000 7 12
    • (2000) Int. J. Biochem. Cell Biol. , vol.32 , pp. 7-12
    • Nakamoto, N.1
  • 15
    • 0036303033 scopus 로고    scopus 로고
    • Mechanisms and functions of Eph and ephrin signaling
    • K. Kullander, and R. Klein Mechanisms and functions of Eph and ephrin signaling Nat. Cell Biol. 3 2002 475 486
    • (2002) Nat. Cell Biol. , vol.3 , pp. 475-486
    • Kullander, K.1    Klein, R.2
  • 16
    • 0034626791 scopus 로고    scopus 로고
    • Regulation of repulsion versus adhesion by different splice forms of an Eph receptor
    • J. Holmberg, D.L. Clarke, and J. Frisen Regulation of repulsion versus adhesion by different splice forms of an Eph receptor Nature 408 2000 203 206
    • (2000) Nature , vol.408 , pp. 203-206
    • Holmberg, J.1    Clarke, D.L.2    Frisen, J.3
  • 17
    • 0030774904 scopus 로고    scopus 로고
    • Eph-related receptors and their ligands: Mediators of contact dependent cell interactions
    • Q. Xu, and D.G. Wilkinson Eph-related receptors and their ligands: mediators of contact dependent cell interactions J. Mol. Med. 75 1997 576 586
    • (1997) J. Mol. Med. , vol.75 , pp. 576-586
    • Xu, Q.1    Wilkinson, D.G.2
  • 18
    • 0036445885 scopus 로고    scopus 로고
    • Vascular patterning by Eph receptor tyrosine kinases and ephrins
    • R.H. Adams Vascular patterning by Eph receptor tyrosine kinases and ephrins Semin. Cell Dev. Biol. 13 2002 55 60
    • (2002) Semin. Cell Dev. Biol. , vol.13 , pp. 55-60
    • Adams, R.H.1
  • 19
    • 0031445587 scopus 로고    scopus 로고
    • The Eph family in the patterning of neural development
    • U. Dresher The Eph family in the patterning of neural development Curr. Biol. 7 1997 R799 R807
    • (1997) Curr. Biol. , vol.7
    • Dresher, U.1
  • 20
    • 0028345221 scopus 로고
    • Expression of two novel eph related receptor protein tyrosine kinases in mammary gland development and carcinogenesis
    • A.C. Andres, H.H. Reid, G. Zürcher, R.J. Blaschke, D. Albrecht, and A. Ziemiecki Expression of two novel eph related receptor protein tyrosine kinases in mammary gland development and carcinogenesis Oncogene 9 1994 1461 1467
    • (1994) Oncogene , vol.9 , pp. 1461-1467
    • Andres, A.C.1    Reid, H.H.2    Zürcher, G.3    Blaschke, R.J.4    Albrecht, D.5    Ziemiecki, A.6
  • 21
    • 0033773863 scopus 로고    scopus 로고
    • Protein tyrosine kinases in malignant melanoma
    • D.J. Easty, and D.C. Bennett Protein tyrosine kinases in malignant melanoma Melanoma Res. 10 2000 401 411
    • (2000) Melanoma Res. , vol.10 , pp. 401-411
    • Easty, D.J.1    Bennett, D.C.2
  • 25
    • 0037455813 scopus 로고    scopus 로고
    • EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma
    • T. Miyazaki, H. Kato, M. Fukuchi, M. Nakajima, and H. Kuwano EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma Int. J. Cancer 103 2003 657 663
    • (2003) Int. J. Cancer , vol.103 , pp. 657-663
    • Miyazaki, T.1    Kato, H.2    Fukuchi, M.3    Nakajima, M.4    Kuwano, H.5
  • 26
    • 0037314612 scopus 로고    scopus 로고
    • Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival
    • M.S. Kinch, M.-B. Moore, and D.J. Harpole Jr. Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival Clin. Cancer Res. 63 2003 613 618
    • (2003) Clin. Cancer Res. , vol.63 , pp. 613-618
    • Kinch, M.S.1    Moore, M.-B.2    Harpole Jr., D.J.3
  • 27
    • 0038068866 scopus 로고    scopus 로고
    • EphA2 overexpression decreases estrogen dependence and tamoxifen sensitivity
    • M. Lu, K.D. Miller, Y. Gokemen-Polar, M.-H. Jeng, and M.S. Kinch EphA2 overexpression decreases estrogen dependence and tamoxifen sensitivity Cancer Res. 63 2003 3425 3429
    • (2003) Cancer Res. , vol.63 , pp. 3425-3429
    • Lu, M.1    Miller, K.D.2    Gokemen-Polar, Y.3    Jeng, M.-H.4    Kinch, M.S.5
  • 29
    • 0032979215 scopus 로고    scopus 로고
    • High level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neroblastomas
    • X.X. Tang, A.E. Evans, H. Zhao, A. Cnaan, W. London, S.L. Cohn, G.M. Brodeur, and N. Ikegaki High level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neroblastomas Clin. Cancer Res. 5 1999 1491 1496
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1491-1496
    • Tang, X.X.1    Evans, A.E.2    Zhao, H.3    Cnaan, A.4    London, W.5    Cohn, S.L.6    Brodeur, G.M.7    Ikegaki, N.8
  • 33
    • 2442419137 scopus 로고    scopus 로고
    • Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application
    • B.P. Fox, and R.P. Kandpal Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application Biochem. Biophys. Res. Commun. 318 2004 882 892
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 882-892
    • Fox, B.P.1    Kandpal, R.P.2
  • 36
    • 22844440606 scopus 로고    scopus 로고
    • Methylation-specific polymerase chain reaction
    • O. Galm, and J.G. Herman Methylation-specific polymerase chain reaction Methods Mol. Med. 113 2005 279 291
    • (2005) Methods Mol. Med. , vol.113 , pp. 279-291
    • Galm, O.1    Herman, J.G.2
  • 37
    • 3042825295 scopus 로고    scopus 로고
    • Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer
    • M.J. Fackler, M. McVeigh, J. Mehrotra, M.A. Blum, J. Lange, A. Lapides, E. Garrett, P. Argani, and S. Sukumar Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer Cancer Res. 64 2004 4442 4452
    • (2004) Cancer Res. , vol.64 , pp. 4442-4452
    • Fackler, M.J.1    McVeigh, M.2    Mehrotra, J.3    Blum, M.A.4    Lange, J.5    Lapides, A.6    Garrett, E.7    Argani, P.8    Sukumar, S.9
  • 39
    • 28044451106 scopus 로고    scopus 로고
    • Gender differences in estrogen receptor alpha promoter hypermethylation and its prognostic value in non-small cell lung cancer
    • J.C. Lai, Y.W. Cheng, H.L. Chiou, M.F. Wu, C.Y. Chen, and H. Lee Gender differences in estrogen receptor alpha promoter hypermethylation and its prognostic value in non-small cell lung cancer Int. J. Cancer 2005 epub ahead of print
    • (2005) Int. J. Cancer
    • Lai, J.C.1    Cheng, Y.W.2    Chiou, H.L.3    Wu, M.F.4    Chen, C.Y.5    Lee, H.6
  • 40
    • 22744444015 scopus 로고    scopus 로고
    • Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer
    • N. Umetani, T. Mori, K. Koyanagi, M. Shinozaki, J. Kim, A.E. Giuliano, and D.S. Hoon Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer Oncogene 24 2005 4721 4727
    • (2005) Oncogene , vol.24 , pp. 4721-4727
    • Umetani, N.1    Mori, T.2    Koyanagi, K.3    Shinozaki, M.4    Kim, J.5    Giuliano, A.E.6    Hoon, D.S.7
  • 43
    • 0141566688 scopus 로고    scopus 로고
    • The correlation between aberrant connexin 43 mRNA expression induced by promoter methylation and nodal micrometastasis in non-small cell lung cancer
    • J.T. Chen, Y.W. Cheng, M.C. Chou, T. Sen-Lin, W.W. Lai, W.L. Ho, and H. Lee The correlation between aberrant connexin 43 mRNA expression induced by promoter methylation and nodal micrometastasis in non-small cell lung cancer Clin. Cancer Res. 11 2003 4200 4204
    • (2003) Clin. Cancer Res. , vol.11 , pp. 4200-4204
    • Chen, J.T.1    Cheng, Y.W.2    Chou, M.C.3    Sen-Lin, T.4    Lai, W.W.5    Ho, W.L.6    Lee, H.7
  • 44
    • 0037370442 scopus 로고    scopus 로고
    • Activation of the early B-cell- specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site
    • H. Maier, J. Colbert, D. Fitzsimmons, D.R. Clark, and J. Hagman Activation of the early B-cell- specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site Mol. Cell. Biol. 6 2003 1946 1960
    • (2003) Mol. Cell. Biol. , vol.6 , pp. 1946-1960
    • Maier, H.1    Colbert, J.2    Fitzsimmons, D.3    Clark, D.R.4    Hagman, J.5
  • 45
    • 0036830198 scopus 로고    scopus 로고
    • Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion
    • Y. Guo, P. Pakneshan, J. Gladu, A. Slack, M. Szyf, and S.A. Rabbani Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion J. Biol. Chem. 44 2002 41571 41579
    • (2002) J. Biol. Chem. , vol.44 , pp. 41571-41579
    • Guo, Y.1    Pakneshan, P.2    Gladu, J.3    Slack, A.4    Szyf, M.5    Rabbani, S.A.6
  • 46
    • 0037427083 scopus 로고    scopus 로고
    • Detection of RASSF1A aberrant promoter hypermethylation in sputum from chronic smokers and ductal carcinoma in situ from breast cancer patients
    • S. Honorio, A. Agathanggelou, M. Schuermann, W. Pankow, O. Viacava, E.R. Maher, and F. Latif Detection of RASSF1A aberrant promoter hypermethylation in sputum from chronic smokers and ductal carcinoma in situ from breast cancer patients Oncogene 22 2005 147 150
    • (2005) Oncogene , vol.22 , pp. 147-150
    • Honorio, S.1    Agathanggelou, A.2    Schuermann, M.3    Pankow, W.4    Viacava, O.5    Maher, E.R.6    Latif, F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.